The antigenic specificity of blood groups which differentiate populations of fresh water catfish.

Erythrocytes derived from fresh water catfish, Ictalurus nebulosus (Le Sueur) and Ictalurus catus (Linneaus), referred to as groups I and II, were capable of eliciting specific immune responses as demonstrated by cross-immunization, stimulation of goats and rabbits, and absorption studies of immune antisera. Two forms of immune response were elicited in goats and rabbits, one against an antigen common to erythrocytes from individuals of groups I and II, and the other against a Forssman-like antigenic substance present on group I, but not group II, erythrocytes. The presence of two classes of immunoglobulins formed during immune responses was suggested on the basis of differences in sensitivity of agglutinins to mercaptoethanol before and after antigenic stimulation. Members of group I possessed a soluble blood group substance in serum and mucus, as demonstrated by agglutination-inhibition tests in the presence of human anti-A antiserum, lima bean lectin, and hemagglutinins in serum from group II individuals.

• Publication year

  1970

• Venue

  Journal of Immunology

• Publication date

  1970-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.105.1.299PMID 5433694
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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