Regulation of PTS gene expression by the homologous transcriptional regulators, Mlc and NagC, in Escherichia coli (or how two similar repressors can behave differently).

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Molecular Microbiology and Biotechnology

• Publication date

  2001-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11361067
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• DNA binding sites for the Mlc and NagC proteins: regulation of nagE, encoding the N-acetylglucosamine-specific transporter in Escherichia coli.

  2001cited by this paper
• Substrate Specificity and Signal Transduction Pathways in the Glucose-Specific Enzyme II (EIIGlc) Component of the Escherichia coli Phosphotransferase System

  2000cited by this paper
• Signal transduction between a membrane‐bound transporter, PtsG, and a soluble transcription factor, Mlc, of Escherichia coli

  2000cited by this paper
• A mutation which affects both the specificity of PtsG sugar transport and the regulation of ptsG expression by Mlc in Escherichia coli.

  2000cited by this paper
• Glucose Transporter Mutants of Escherichia coli K-12 with Changes in Substrate Recognition of IICBGlc and Induction Behavior of theptsG Gene

  2000cited by this paper
• Pathways for the utilization of N‐acetyl‐galactosamine and galactosamine in Escherichia coli

  2000cited by this paper
• A novel regulatory role of glucose transporter of Escherichia coli: membrane sequestration of a global repressor Mlc

  2000influential reference
• Repression of the gene encoding succinate dehydrogenase in response to glucose is mediated by the EIICB(Glc) protein in Escherichia coli.

  1999cited by this paper
• Mutational adaptation of Escherichia coli to glucose limitation involves distinct evolutionary pathways in aerobic and oxygen-limited environments.

  1999cited by this paper
• Negative regulation of the pts operon by Mlc: mechanism underlying glucose induction in Escherichia coli

  1999cited by this paper
• A Mutated PtsG, the Glucose Transporter, Allows Uptake ofd-Ribose*

  1999cited by this paper
• Purification of Mlc and Analysis of Its Effects on thepts Expression in Escherichia coli *

  1999cited by this paper
• Transcription activation by catabolite activator protein (CAP).

  1999cited by this paper
• Regulation by nutrient limitation.

  1999cited by this paper
• Expression of the phosphotransferase system both mediates and is mediated by Mlc regulation in Escherichia coli

  1999cited by this paper
• Adaptive mgl-regulatory mutations and genetic diversity evolving in glucose-limited Escherichia coli populations.

  1999cited by this paper
• Expression of ptsG, the gene for the major glucose PTS transporter in Escherichia coli, is repressed by Mlc and induced by growth on glucose

  1998cited by this paper
• The ATP‐binding cassette subunit of the maltose transporter MalK antagonizes MalT, the activator of the Escherichia coli mal regulon

  1998influential reference
• PRD — a protein domain involved in PTS‐dependent induction and carbon catabolite repression of catabolic operons in bacteria

  1998cited by this paper
• Control of the expression of the manXYZ operon in Escherichia coli: Mlc is a negative regulator of the mannose PTS

  1998cited by this paper
• A global repressor (Mlc) is involved in glucose induction of the ptsG gene encoding major glucose transporter in Escherichia coli

  1998cited by this paper
• DNA bending and expression of the divergent nagE-B operons.

  1998cited by this paper
• Growth Kinetics of Suspended Microbial Cells: From Single-Substrate-Controlled Growth to Mixed-Substrate Kinetics

  1998cited by this paper
• Negative transcriptional regulation of a positive regulator: the expression of malT, encoding the transcriptional activator of the maltose regulon of Escherichia coli, is negatively controlled by Mlc

  1998cited by this paper
• Regulation of gene expression by repressor localization: biochemical evidence that membrane and DNA binding by the PutA protein are mutually exclusive

  1997cited by this paper
• Repressor induced site‐specific binding of HU for transcriptional regulation

  1997cited by this paper
• Wild-type Escherichia coli grows on the chitin disaccharide, N,N'-diacetylchitobiose, by expressing the cel operon.

  1997cited by this paper
• The relationship between external glucose concentration and cAMP levels inside Escherichia coli: implications for models of phosphotransferase-mediated regulation of adenylate cyclase.

  1997cited by this paper
• Functional characterization of roles of GalR and GalS as regulators of the gal regulon

  1997cited by this paper
• Characterization of TreR, the Major Regulator of the Escherichia coli Trehalose System*

  1997cited by this paper
• Contribution of glucose kinase to glucose repression of xylose utilization in Bacillus megaterium

  1997cited by this paper
• Structure of the lactose operon repressor and its complexes with DNA and inducer

  1996influential reference
• Molecular analysis of the gat genes from Escherichia coli and of their roles in galactitol transport and metabolism

  1996cited by this paper
• The catabolite repressor/activator (Cra) protein of enteric bacteria

  1996influential reference
• Histone‐like protein HU as a specific transcriptional regulator: co‐factor role in repression of gal transcription by GAL repressor

  1996cited by this paper
• A flexible partnership: the CytR anti‐activator and the cAMP–CRP activator protein, comrades in transcription control

  1996cited by this paper
• Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer

  1996cited by this paper
• Decreasing accumulation of acetate in a rich medium by Escherichia coli on introduction of genes on a multicopy plasmid.

  1995cited by this paper
• Effect of the FruR Regulator on Transcription of the pts Operon in Escherichia coli(*)

  1995cited by this paper
• Co‐ordinated regulation of amino sugar biosynthesis and degradation: the NagC repressor acts as both an activator and a repressor for the transcription of the glmUS operon and requires two separated NagC binding sites.

  1995cited by this paper
• Nag repressor-operator interactions: protein-DNA contacts cover more than two turns of the DNA helix.

  1995cited by this paper
• Glucose and glucose-6-phosphate interaction with Xyl repressor proteins from Bacillus spp. may contribute to regulation of xylose utilization

  1995cited by this paper
• Regulation of xylose utilization in Bacillus licheniformis: Xyl repressor‐xyl‐operator interaction studied by DNA modification protection and interference

  1994cited by this paper
• The mannitol repressor (MtlR) of Escherichia coli

  1994cited by this paper
• Glucose repression in Streptomyces coelicolor A3(2): a likely regulatory role for glucose kinase

  1994cited by this paper
• Evolutionary relationships between sugar kinases and transcriptional repressors in bacteria.

  1994cited by this paper
• Organisation and Characteristics of Criminal Firms

  1994cited by this paper
• Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.

  1994influential reference
• Promoter switch in the Escherichia coli pts operon.

  1994cited by this paper
• DNA loop formation between Nag repressor molecules bound to its two operator sites is necessary for repression of the nag regulon of Escherichia coli in vivo

  1993cited by this paper
• In vitro binding of the pleiotropic transcriptional regulatory protein, FruR, to the fru, pps, ace, pts and icd operons of Escherichia coli and Salmonella typhimurium.

  1993cited by this paper
• PutA protein, a membrane-associated flavin dehydrogenase, acts as a redox-dependent transcriptional regulator.

  1993cited by this paper
• Coordinated regulation of amino sugar-synthesizing and -degrading enzymes in Escherichia coli K-12

  1993cited by this paper
• Identification of the functional subunit of a dimeric transcription activator protein by use of oriented heterodimers.

  1993cited by this paper
• The glucose transporter of Escherichia coli

  1993cited by this paper
• The glucose kinase gene of Streptomyces coelicolor A3(2): its nucleotide sequence, transcriptional analysis and role in glucose repression

  1992cited by this paper
• Isorepressor of the gal regulon in Escherichia coli.

  1992cited by this paper
• A family of bacterial regulators homologous to Gal and Lac repressors.

  1992cited by this paper
• Evidence for two promoters upstream of the pts operon: regulation by the cAMP receptor protein regulatory complex.

  1992cited by this paper
• Positive regulation of the expression of the Escherichia coli pts operon. Identification of the regulatory regions.

  1992cited by this paper
• DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.

  1992cited by this paper
• Regulation of the Bacillus subtilis W23 xylose utilization operon : interaction of the Xyl repressor with the xyl operator and the inducer xylose

  1992cited by this paper
• CAP and Nag repressor binding to the regulatory regions of the nagE-B and manX genes of Escherichia coli.

  1991cited by this paper
• Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees

  1991cited by this paper
• Organization, promoter analysis and transcriptional regulation of the Staphylococcus xylosus xylose utilization operon

  1991cited by this paper
• The malX malY operon of Escherichia coli encodes a novel enzyme II of the phosphotransferase system recognizing glucose and maltose and an enzyme abolishing the endogenous induction of the maltose system

  1991cited by this paper
• Positive regulation of the pts operon of Escherichia coli: genetic evidence for a signal transduction mechanism

  1991cited by this paper
• Organization and characterization of three genes involved in d-xylose catabolism in Lactobacillus pentosus

  1991cited by this paper
• Repression and induction of the nag regulon of Escherichia coll K‐12: the roles of nagC and nagA in maintenance of the uninduced state

  1991cited by this paper
• Rules for Protein DNA Recognition for a Family of Helix-Turn-Helix Proteins

  1991cited by this paper
• Comparison of the sequences of the nagE operons from Klebsiella pneumoniae and Escherichia colt K12: Enhanced variability of the enzyme IIN-acetylglucosamine in regions connecting functional domains

  1991cited by this paper
• Cloning and characterization of the N-acetylglucosamine operon of Escherichia coli.

  1990cited by this paper
• Erratum: Cloning and characterization of the N-acetylglucosamine operon Escherichia coli

  1990cited by this paper
• Characterization and nucleotide sequence of the cryptic cel operon of Escherichia coli K12.

  1990cited by this paper
• MalI, a novel protein involved in regulation of the maltose system of Escherichia coli, is highly homologous to the repressor proteins GalR, CytR, and LacI

  1989cited by this paper
• Analysis of the nag regulon from Escberichia coli K12 and Klebsiella pneumoniae and of its regulation

  1989cited by this paper
• Sequence of the nagBACD operon in Escherichia coli K12 and pattern of transcription within the nag regulon

  1989cited by this paper
• Nucleotide sequences of the Escherichia coli nagE and nagB genes: the structural genes for the N-acetylglucosamine transport protein of the bacterial phosphoenolpyruvate: sugar phosphotransferase system and for glucosamine-6-phosphate deaminase.

  1988cited by this paper
• Positive and negative regulators for glucitol (gut) operon expression in Escherichia coli.

  1988cited by this paper
• Sequence of cloned enzyme IIN-acetylglucosamine of the phosphoenolpyruvate:N-acetylglucosamine phosphotransferase system of Escherichia coli.

  1988cited by this paper
• Sequence of cloned enzyme IIN-acetylglucosamine of the phosphoenolpyruvate:N-acetylglucosamine phosphotransferase system of Escherichia coli.

  1988cited by this paper
• Regulation of the bgl operon of Escherichia coli by transcriptional antitermination.

  1988cited by this paper
• Suppression of IIIGlc‐defects by Enzymes IINag and IIBgl of the PEP:carbohydrate phosphotransferase system

  1988cited by this paper
• A bacterial gene involved in transcription antitermination: regulation at a rho-independent terminator in the bgl operon of E. coli.

  1987cited by this paper
• Glucose-permease of the bacterial phosphotransferase system. Gene cloning, overproduction, and amino acid sequence of enzyme IIGlc.

  1986influential reference
• Purification, molecular and kinetic properties of glucosamine-6-phosphate isomerase (deaminase) from Escherichia coli.

  1984cited by this paper
• Genetic locus, distant from ptsM, affecting enzyme IIA/IIB function in Escherichia coli K-12

  1980cited by this paper
• Regulation of carbohydrate uptake and adenylate cyclase activity mediated by the enzymes II of the phosphoenolpyruvate: sugar phosphotransferase system in Escherichia coli.

  1976influential reference
• PtsX: A Gene involved in the uptake of glucose and fructose by Escherichia coli

  1975cited by this paper
• Phosphorylation of D-glucose in Escherichia coli mutants defective in glucosephosphotransferase, mannosephosphotransferase, and glucokinase

  1975cited by this paper
• Inducible phosphoenolpyruvate-dependent hexose phosphotransferase activities in Escherichia coli.

  1972influential reference
• Control of amino sugar metabolism in Escherichia coli and isolation of mutants unable to degrade amino sugars.

  1968cited by this paper
• Effect of Amino Sugars on Catabolite Repression in Escherichia coli

  1968cited by this paper

• BadR directly represses the expression of the glycerol utilization operon in the Lyme disease pathogen

  2024cites this paper
• Unexpected proteins involved in the regulation of secondary metabolism in Myxococcus xanthus DK1622

  2024cites this paper
• ROK family regulator NagC promotes prodigiosin biosynthesis independent of N-acetylglucosamine in Serratia sp. ATCC 39006

  2024cites this paper
• Arginine glycosylation regulates UDP-GlcNAc biosynthesis in Salmonella enterica

  2022cites this paper
• A mannose-sensing AraC-type transcriptional activator regulates cell–cell aggregation of Vibrio cholerae

  2022cites this paper
• Mechanism of repression of the glycerol utilization operon in Borrelia burgdorferi

  2022cites this paper
• A mannose-sensing AraC-type transcriptional activator regulates cell–cell aggregation of Vibrio cholerae

  2022cites this paper
• Vibrio cholerae FruR facilitates binding of RNA polymerase to the fru promoter in the presence of fructose 1-phosphate

  2021cites this paper
• Functional dissection of the phosphotransferase system provides insight into the prevalence of Faecalibacterium prausnitzii in the host intestinal environment.

  2021cites this paper
• The mannose phosphotransferase system (Man-PTS) - Mannose transporter and receptor for bacteriocins and bacteriophages.

  2020cites this paper
• The ROK like protein of Myxococcus xanthus DK1622 acts as a pleiotropic transcriptional regulator for secondary metabolism.

  2020cites this paper
• The ROK-family Regulator Rok7B7 Directly Controls Carbon Catabolite Repression, Antibiotic Biosynthesis, and Morphological Development in Streptomyces avermitilis.

  2020cites this paper
• Mapping and refactoring pathway control through metabolic and protein engineering: The hexosamine biosynthesis pathway.

  2020cites this paper
• Impact of Combined Acidic and Hyperosmotic Shock Conditions on the Proteome ofListeria monocytogenesATCC 19115 in a Time-Course Study

  2019cites this paper
• Systems metabolic engineering of Escherichia coli improves co-conversion of lignocellulose-derived sugars.

  2019cites this paper
• Complex synergistic amino acid-nucleotide interactions contribute to the specificity of NagC operator recognition and induction.

  2019cites this paper
• University of Groningen Engineering of sugar metabolism in Lactococcus lactis Pool, Weia Arianne

  2018cites this paper
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  2017cites this paper
• Identification of New Genes Related to Virulence of Xanthomonas axonopodis Pv. Citri during Citrus Host Interactions

  2017cites this paper
• Engineering of sugar metabolism in Lactococcus lactis Pool ,

  2017cites this paper
• Characterization of DNA Binding Sites of RokB, a ROK-Family Regulator from Streptomyces coelicolor Reveals the RokB Regulon

  2016cites this paper
• N-acetylglucosamine-Mediated Expression of nagA and nagB in Streptococcus pneumoniae

  2016cites this paper
• Dual inducer signal recognition by an Mlc homologue.

  2015cites this paper
• Regulation of the Utilization of Amino Sugars by Escherichia coli and Bacillus subtilis: Same Genes, Different Control

  2015cites this paper
• Transcription of Two Adjacent Carbohydrate Utilization Gene Clusters in Bifidobacterium breve UCC2003 Is Controlled by LacI- and Repressor Open Reading Frame Kinase (ROK)-Type Regulators

  2014cites this paper
• The involvement of transport proteins in transcriptional and metabolic regulation.

  2014cites this paper
• Operator recognition by the ROK transcription factor family members, NagC and Mlc

  2014cites this paper
• Chitin hydrolysis and N-acetylglucosamine utilization by solventogenic clostridia

  2013influential citation
• Borrelia host adaptation Regulator (BadR) regulates rpoS to modulate host adaptation and virulence factors in Borrelia burgdorferi

  2013cites this paper
• Étude et comparaison de l'utilisation des sucres aminés chez E.coli et chez B.subtilis

  2012cites this paper
• Functional diversification of ROK-family transcriptional regulators of sugar catabolism in the Thermotogae phylum

  2012cites this paper
• The linker sequence, joining the DNA‐binding domain of the homologous transcription factors, Mlc and NagC, to the rest of the protein, determines the specificity of their DNA target recognition in Escherichia coli

  2012cites this paper
• The small RNA SgrS controls sugar–phosphate accumulation by regulating multiple PTS genes

  2011cites this paper
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  2011cites this paper
• Regulon of the N-Acetylglucosamine Utilization Regulator NagR in Bacillus subtilis

  2011cites this paper
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  2008cites this paper
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• The dual transcriptional regulator CysR in Corynebacterium glutamicum ATCC 13032 controls a subset of genes of the McbR regulon in response to the availability of sulphide acceptor molecules

  2008cites this paper
• Molekularbiologische Charakterisierung des Glukose-Phosphotransferase-System Regulators MtfA aus Escherichia coli K-12

  2007cites this paper
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  2007cites this paper
• Regulation of the chitobiose–phosphotransferase system in Vibrio cholerae

  2007cites this paper
• Crystallization and preliminary X-ray analysis of Mlc from Escherichia coli.

  2005cites this paper
• X-ray crystallographic studies on Mlc and Aes, two transcriptional modulators from Escherichia coli

  2005cites this paper
• X-ray crystallographic studies on Mlc and Aes, two transcriptional modulators from Escherichia coli

  2005influential citation
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  2004cites this paper
• Global control of sugar metabolism: a Gram-positive solution

  2004cites this paper
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  2004cites this paper
• Phosphoenolpyruvate phosphotransferase system and N-acetylglucosamine metabolism in Bacillus sphaericus.

  2003cites this paper
• Analysis of the Interaction between the Global Regulator Mlc and EIIBGlc of the Glucose-specific Phosphotransferase System in Escherichia coli *

  2003cites this paper
• Carbohydrate-induced Differential Gene Expression Patterns in the Hyperthermophilic Bacterium Thermotoga maritima * 210

  2003cites this paper
• Studies on the Escherichia coli glucose-specific permease, PtsG, with a point mutation in its N-terminal amphipathic leader sequence.

  2003cites this paper
• Genomic Analysis and Initial Characterization of the Chitinolytic System of Microbulbifer degradans Strain 2-40

  2003cites this paper
• Global Gene Expression Differences Associated with Changes in Glycolytic Flux and Growth Rate in Escherichia coli during the Fermentation of Glucose and Xylose

  2002cites this paper
• Carbon catabolite repression in bacteria: choice of the carbon source and autoregulatory limitation of sugar utilization.

  2002cites this paper
• Regulation of gene expression in the PTS in Escherichia coli: the role and interactions of Mlc.

  2002cites this paper
• Global control of sugar metabolism: a gram-positive solution.

  2002cites this paper