p 160 ROCK mediates RhoA activation of Na – H exchange

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  2013

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• Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading.

  1998cited by this paper
• p160ROCK, a Rho‐associated coiled‐coil forming protein kinase, works downstream of Rho and induces focal adhesions

  1997cited by this paper
• Integrins, Oncogenes, and Anchorage Independence

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• Interaction of PKN with α-Actinin*

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  1997cited by this paper
• Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

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• Integrin-dependent translocation of p160ROCK to cytoskeletal complex in thrombin-stimulated human platelets.

  1997cited by this paper
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  1996cited by this paper
• Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

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  1996cited by this paper
• ROCK‐I and ROCK‐II, two isoforms of Rho‐associated coiled‐coil forming protein serine/threonine kinase in mice

  1996cited by this paper
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  1996cited by this paper
• Mapping of Ankyrin Binding Determinants on the Erythroid Anion Exchanger, AE1*

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• Modulation of Band 3-Ankyrin Interaction by Protein 4.1

  1996influential reference
• The links between cellular Ca2+ and Na+/H+ exchange in the pathophysiology of essential hypertension.

  1996cited by this paper
• Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho

  1996cited by this paper
• The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

  1996influential reference
• G alpha 13 stimulates Na+-H+ exchange through distinct Cdc42-dependent and RhoA-dependent pathways.

  1996cited by this paper
• Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

  1996cited by this paper
• Rho‐associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

  1996cited by this paper
• Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)*

  1996influential reference
• Role of Rho in Chemoattractant-Activated Leukocyte Adhesion Through Integrins

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• Identification of a Putative Target for Rho as the Serine-Threonine Kinase Protein Kinase N

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• A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes (*)

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  1995cited by this paper
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• G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly.

  1995cited by this paper
• An essential role for Rac in Ras transformation

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• Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex.

  1995cited by this paper
• Salt-Sensitive Hypertension in Transgenic Mice Overexpressing Na+-Proton Exchanger

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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• The carboxyl-terminal region of the Na+/H+ exchanger interacts with mammalian heat shock protein.

  1995cited by this paper
• The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases

  1995cited by this paper
• Long-term expression of c-H-ras stimulates Na-H and Na(+)-dependent Cl-HCO3 exchange in NIH-3T3 fibroblasts.

  1994cited by this paper
• Mutation of calmodulin-binding site renders the Na+/H+ exchanger (NHE1) highly H(+)-sensitive and Ca2+ regulation-defective.

  1994cited by this paper
• G alpha 13 stimulates Na-H exchange.

  1994cited by this paper
• Growth factor activation and "H(+)-sensing" of the Na+/H+ exchanger isoform 1 (NHE1). Evidence for an additional mechanism not requiring direct phosphorylation.

  1994cited by this paper
• Protein kinase C-dependent and -independent activation of Na+/H+ exchanger by G alpha 12 class of G proteins.

  1994cited by this paper
• ATP dependence of NHE-1, the ubiquitous isoform of the Na+/H+ antiporter. Analysis of phosphorylation and subcellular localization.

  1994cited by this paper
• Focal localization of the NHE‐1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH.

  1993cited by this paper
• Role of cytoplasmic domain of the Na+/H+ exchanger in hormonal activation.

  1993cited by this paper
• A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs

  1993cited by this paper
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  1993cited by this paper
• ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle.

  1993cited by this paper
• Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)

  1993cited by this paper
• The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors.

  1992influential reference
• The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing".

  1992cited by this paper
• Activation of the Na+/H+ antiporter during cell volume regulation. Evidence for a phosphorylation-independent mechanism.

  1992cited by this paper
• Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape.

  1991cited by this paper
• Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites.

  1991influential reference
• ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility.

  1991cited by this paper
• Control of intracellular pH and growth by fibronectin in capillary endothelial cells

  1990influential reference
• Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation.

  1989cited by this paper
• Ha-ras activates the Na+/H+ antiporter by a protein kinase C-independent mechanism.

  1989cited by this paper
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  1986cited by this paper
• Complexes of polyoma virus medium T antigen and cellular proteins.

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• A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH.

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  1979cited by this paper
• Intracellular pH transients in squid giant axons caused by CO2, NH3, and metabolic inhibitors

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