Naturally-occurring hemagglutinin in a tunicate Halocynthia pyriformis.

An active, naturally-occurring panhemagglutinin has been described in the hemolymph of the protochordate Halocynthia pyriformis. This protein lectin is inactivated by temperatures exceeding 50° C, is active in the range pH 6-10, and is resistant to repeated freezing and thawing. Frozen hemolymph retains full hemagglutinating activity for several months. Activity is not reduced by dialysis against saline; however, serum proteins with total hemagglutinating activity can be precipitated by dialysis against deionized water or by treatment with appropriate ammonium sulfate concentrations. This lectin will not agglutinate human erythrocytes in the absence of Ca++; Ca++ potentiates the agglutination of red cells from all other species tested. However, Mg++ does not stimulate hemagglutination and will inhibit it at certain concentrations.Halocynthia pyriformis hemolymph will cause the agglutination of red cells from many avian and mammalian species. Human, rabbit, sheep, swine, goat, calf, ox, and pigeon erythroc...

• Publication year

  1975

• Venue

  The Biological Bulletin

• Publication date

  1975-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2307/1540513PMID 239759
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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