Innate Antifungal Immunity of Human Eosinophils Mediated by a β2 Integrin, CD11b1

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Immunology

• Publication date

  2008-08-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.181.4.2907PMCID PMC2614918
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• A chitinase-like protein in the lung and circulation of patients with severe asthma.

  2007cited by this paper
• Dectin-1 is required for β-glucan recognition and control of fungal infection

  2007cited by this paper
• Exoskeletons and exhalation.

  2007cited by this paper
• CD66b Regulates Adhesion and Activation of Human Eosinophils1

  2007cited by this paper
• Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

  2007cited by this paper
• Chitin induces accumulation in tissue of innate immune cells associated with allergy

  2007cited by this paper
• The link between fungi and severe asthma: a summary of the evidence

  2006cited by this paper
• The structure and synthesis of the fungal cell wall

  2006cited by this paper
• The role of ubiquitous airborne fungi in chronic rhinosinusitis

  2006cited by this paper
• Dectin-1: a signalling non-TLR pattern-recognition receptor

  2006cited by this paper
• The role of Th2 cytokines, chemokines and parasite products in eosinophil recruitment to the gastrointestinal mucosa during helminth infection

  2006cited by this paper
• Exposure to Alternaria alternata in US homes is associated with asthma symptoms.

  2006cited by this paper
• Toll-like receptors.

  2005cited by this paper
• Critical role for complement receptor 3 (CD11b/CD18), but not for Fc receptors, in killing of Streptococcus pyogenes by neutrophils in human immune serum

  2005cited by this paper
• Nonpathogenic, Environmental Fungi Induce Activation and Degranulation of Human Eosinophils1

  2005cited by this paper
• Striking deposition of toxic eosinophil major basic protein in mucus: implications for chronic rhinosinusitis.

  2005cited by this paper
• Epidemiology of alternaria alternata allergy: a prospective study in 6840 Italian asthmatic children.

  2004cited by this paper
• Chitin checking--novel insights into asthma.

  2004cited by this paper
• Acidic Mammalian Chitinase in Asthmatic Th2 Inflammation and IL-13 Pathway Activation

  2004cited by this paper
• Alternaria-induced asthma.

  2004cited by this paper
• Correlation of Serum Total IgE, Eosinophil Granule Cationic Proteins, Sensitized Allergens and Family Aggregation in Atopic Dermatitis Patients with or without Rhinitis

  2004cited by this paper
• The role of eosinophils in host defense against helminth parasites.

  2004cited by this paper
• Innate and cognate mechanisms of pulmonary eosinophilia in helminth infection

  2002cited by this paper
• Fungicidal effect of antimicrobial peptide, PMAP-23, isolated from porcine myeloid against Candida albicans.

  2001cited by this paper
• Immune recognition: A new receptor for β-glucans

  2001cited by this paper
• Eosinophil granule proteins and their role in disease

  2001cited by this paper
• Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens

  2001cited by this paper
• Dendritic Cells Discriminate between Yeasts and Hyphae of the Fungus Candida albicans

  2000cited by this paper
• The role of eosinophils in parasitic helminth infections: insights from genetically modified mice.

  2000cited by this paper
• The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells.

  1999cited by this paper
• Ligation of Fc gamma RII (CD32) pivotally regulates survival of human eosinophils.

  1999influential reference
• Allergy: Principles and Practice

  1999cited by this paper
• Deposition of eosinophil-granule major basic protein and expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in the mucosa of the small intestine in infants with cow's milk-sensitive enteropathy.

  1999cited by this paper
• Localization of eosinophil granule major basic protein in paracoccidioidomycosis lesions.

  1998cited by this paper
• Soluble Fcgamma receptor type III (FcgammaRIII, CD16) triggers cell activation through interaction with complement receptors.

  1996cited by this paper
• Soluble beta-glucan polysaccharide binding to the lectin site of neutrophil or natural killer cell complement receptor type 3 (CD11b/CD18) generates a primed state of the receptor capable of mediating cytotoxicity of iC3b-opsonized target cells.

  1996cited by this paper
• [Allergic bronchopulmonary aspergillosis].

  1996cited by this paper
• Analysis of the sugar specificity and molecular location of the beta-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18).

  1996cited by this paper
• Ammonium chloride exposure inhibits cytokine-mediated eosinophil survival.

  1994cited by this paper
• The role of eosinophils in the pathogenesis of atopic dermatitis ‐ eosinophil granule proteins as markers of disease activity

  1993cited by this paper
• The influence of IL-3, IL-5, and GM-CSF on normal human eosinophil and neutrophil C3b-induced degranulation.

  1993cited by this paper
• In vitro killing of microfilariae of Brugia pahangi and Brugia malayi by eosinophil granule proteins.

  1990cited by this paper
• Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action.

  1990cited by this paper
• Antibacterial properties of eosinophil major basic protein and eosinophil cationic protein.

  1989cited by this paper
• Functional role of the alpha-chain of complement receptor type 3 in human eosinophil-dependent antibody-mediated cytotoxicity against schistosomes.

  1987cited by this paper
• Dermal deposition of eosinophil-granule major basic protein in atopic dermatitis. Comparison with onchocerciasis.

  1985cited by this paper
• 199 Localization of eosinophil granule major basic protein in chronic urticaria

  1983cited by this paper
• An immunofluorescent method for specific staining of eosinophil granule major basic protein.

  1981influential reference
• Damage to schistosomula of Schistosoma mansoni induced directly by eosinophil major basic protein.

  1979cited by this paper
• [Biology of eosinophils].

  1978cited by this paper

• Eosinophil CD48 interactions with Candida albicans Als6 is protective in vitro and in mouse systemic candidiasis

  2025cites this paper
• Study of the Effectiveness of Skin Restoration Using a Biopolymer Hydrogel Scaffold with Encapsulated Mesenchymal Stem Cells

  2025cites this paper
• Signaling events driving Aspergillus fumigatus-induced eosinophil activation.

  2024cites this paper
• Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease

  2024cites this paper
• Eosinophils as Modulators of Host Defense during Parasitic, Fungal, Bacterial, and Viral Infections.

  2024cites this paper
• The Road Ahead: Advancing Antifungal Vaccines and Addressing Fungal Infections in the Post-COVID World.

  2024cites this paper
• Novel mechanistic insights underlying fungal allergic inflammation

  2023cites this paper
• Aspergillus Enhances Eosinophil and Neutrophil Extracellular DNA Trap Formation in Chronic Rhinosinusitis

  2023cites this paper
• Eosinophils—from cradle to grave

  2023cites this paper
• Immunopathologic Role of Eosinophils in Eosinophilic Chronic Rhinosinusitis

  2022cites this paper
• Allergic fungal diseases in the upper and lower airways

  2022cites this paper
• Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling

  2022cites this paper
• Japanese cedar pollen upregulates the effector functions of eosinophils

  2021cites this paper
• Neutrophil and Eosinophil DNA Extracellular Trap Formation: Lessons From Pathogenic Fungi

  2021cites this paper
• Initiation and Pathogenesis of Severe Asthma with Fungal Sensitization

  2021cites this paper
• Revisiting the controversy: The role of fungi in chronic rhinosinusitis

  2021cites this paper
• Immune Cell Degranulation in Fungal Host Defence

  2021cites this paper
• Multiple Biological Aspects of Eosinophils in Host Defense, Eosinophil-Associated Diseases, Immunoregulation, and Homeostasis: Is Their Role Beneficial, Detrimental, Regulator, or Bystander?

  2020cites this paper
• Eosinophils in the Tumor Microenvironment.

  2020cites this paper
• Eosinophils in transbronchial biopsies: a predictor of chronic lung allograft dysfunction and reduced survival after lung transplantation — a retrospective single‐center cohort study

  2020cites this paper
• Airway mycosis in allergic airway disease.

  2019cites this paper
• Incidence of Eosinophilia Inrural Population of Northern Region of Kashmir in India (A Study at Tertiary Care Hospital)

  2019cites this paper
• Dysregulated fatty acid metabolism in nasal polyp‐derived eosinophils from patients with chronic rhinosinusitis

  2019cites this paper
• Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans

  2019cites this paper
• Allergic Bronchopulmonary Aspergillosis–A Luminal Hypereosinophilic Disease With Extracellular Trap Cell Death

  2018influential citation
• Human eosinophils and mast cells: Birds of a feather flock together

  2018cites this paper
• Eosinophils in fungal diseases: An overview

  2018cites this paper
• Eosinophils from Physiology to Disease: A Comprehensive Review

  2018cites this paper
• Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets

  2018cites this paper
• Innate and adaptive immune responses to fungi in the airway

  2018cites this paper
• Correlation of Symptoms, Clinical Signs, and Biomarkers of Inflammation in Postsurgical Chronic Rhinosinusitis

  2017cites this paper
• Eosinophils release extracellular DNA traps in response to Aspergillus fumigatus

  2017cites this paper
• 5 – Inflammatory and Effector Cells/Cell Migration

  2016cites this paper
• Mechanisms regulating airway responses to the fungal allergen Alternaria alternata

  2016cites this paper
• A Player and Coordinator: The Versatile Roles of Eosinophils in the Immune System

  2016cites this paper
• Eosinophilic bioactivities in severe asthma

  2016cites this paper
• Effect of eosinophils activated with Alternaria on the production of extracellular matrix from nasal fibroblasts.

  2016cites this paper
• International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

  2016cites this paper
• The Eosinophil in Infection

  2016cites this paper
• The innate immune response to Aspergillus fumigatus at the alveolar surface.

  2015cites this paper
• Chitin, a key factor in immune regulation: lesson from infection with fungi and chitin bearing parasites

  2015cites this paper
• Biological basis and clinical implications of immunological molecules involved in eosinophilic inflammation in allergic rhinitis, chronic rhinosinusitis, and asthma

  2015cites this paper
• Oral and Topical Antifungals

  2015cites this paper
• Primary lysis of eosinophils in severe desquamative asthma

  2014cites this paper
• Eosinophils Are Recruited in Response to Chitin Exposure and Enhance Th2-Mediated Immune Pathology in Aspergillus fumigatus Infection

  2014cites this paper
• Role of prostaglandin D2/CRTH2 pathway on asthma exacerbation induced by Aspergillus fumigatus

  2014cites this paper
• Eosinophil Secretion of Granule-Derived Cytokines

  2014cites this paper
• Induction of innate immunity by Aspergillus fumigatus cell wall polysaccharides is enhanced by the composite presentation of chitin and beta-glucan.

  2014cites this paper
• Effect of antibiotic use and mold exposure in infancy on allergic rhinitis in susceptible adolescents.

  2014cites this paper
• Eosinophils in Fungus-Associated Allergic Pulmonary Disease

  2013cites this paper
• Produces Potent Th2 Adjuvant Activity Alternaria, Activates Dendritic Cells and Asthma-Related Environmental Fungus,

  2013cites this paper
• The role of eosinophils in rhinologic diseases

  2013cites this paper
• Eosinophil Signal Transduction

  2013cites this paper
• Activation des polynucléaires (basophiles, neutrophiles et éosinophiles) par les allergènes alimentaires dans les allergies alimentaires IgE dépendantes de l’enfant

  2013cites this paper
• Vertebrate immune system evolution and comparative primate immunity

  2013cites this paper
• Eosinophils: Multifunctional and Distinctive Properties

  2013cites this paper
• Chitin Elicits CCL2 from Airway Epithelial Cells and Induces CCR2-Dependent Innate Allergic Inflammation in the Lung

  2012cites this paper
• Oral antifungal therapy for Fusarium‐associated chronic rhinosinusitis

  2012cites this paper
• Pattern‐recognition receptors in human eosinophils

  2012cites this paper
• Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens

  2012cites this paper
• Innate Immunity to Candida Infections

  2012cites this paper
• Eosinophils and Anti-Pathogen Host Defense

  2012cites this paper
• Alternaria Fungus Induces the Production of GM-CSF, Interleukin-6 and Interleukin-8 and Calcium Signaling in Human Airway Epithelium through Protease-Activated Receptor 2

  2012cites this paper
• Human Eosinophil Innate Response to Alternaria Fungus through Protease-Activated Receptor-2

  2011cites this paper
• The individual and unique roles for eosinophils and interleukin-5 in the innate immune response to sepsis

  2011influential citation
• Eosinophils: multifaceted biological properties and roles in health and disease

  2011cites this paper
• Seeking common pathophysiology in asthma, atopy and sinusitis.

  2011cites this paper
• Mechanisms underlying pulmonary neutrophilia versus eosinophilia in fungal allergy

  2011cites this paper
• Fungal Chitin from Asthma-Associated Home Environments Induces Eosinophilic Lung Infiltration

  2011cites this paper
• Human Eosinophils Recognize Endogenous Danger Signal Crystalline Uric Acid and Produce Proinflammatory Cytokines Mediated by Autocrine ATP

  2010cites this paper
• [Eosinophil: a new effector of innate immunity?].

  2010cites this paper
• Fungal-Induced Inflammation and Nasal Polyps

  2010cites this paper
• The Role of the House Dust Mite-Induced Innate Immunity in Development of Allergic Response

  2010cites this paper
• Eosinophil Survival and Apoptosis in Health and Disease

  2010cites this paper
• Eosinophils in innate immunity: an evolving story

  2010cites this paper
• Endotoxins and β-glucans as markers of microbiological contamination--characteristics, detection, and environmental exposure.

  2010cites this paper
• Pathogenesis of invasive candidiasis

  2010cites this paper
• A 42-year-old woman with chronic rhinosinusitis and allergic mucin

  2009cites this paper
• Asthma-Related Environmental Fungus, Alternaria, Activates Dendritic Cells and Produces Potent Th2 Adjuvant Activity1

  2009cites this paper
• Recognition of Fungal Protease Activities Induces Cellular Activation and Eosinophil-Derived Neurotoxin Release in Human Eosinophils1

  2009cites this paper
• Produces Potent Th 2 Adjuvant Activity , Activates Dendritic Cells and Alternaria Asthma-Related Environmental Fungus , Hirohito

  2009cites this paper
• Histoplasma capsulatum Cell Wall β-Glucan Induces Lipid Body Formation through CD18, TLR2, and Dectin-1 Receptors: Correlation with Leukotriene B4 Generation and Role in HIV-1 Infection1

  2009cites this paper
• The mold conundrum in chronic hyperplastic sinusitis

  2009cites this paper
• Fungus as the cause of chronic rhinosinusitis: the case remains unproven

  2009cites this paper
• Invariant NKT Cells Regulate Experimental Autoimmune Encephalomyelitis and Infiltrate the Central Nervous System in a CD1d-Independent Manner1

  2008cites this paper