The Genetic Variant Voila1 Causes Gustatory Defects during Drosophila Development

Voila1, an enhancer-trap strain in Drosophila melanogaster, expresses GAL4 in most gustatory neurons, both before and after metamorphosis.Voila1 expression starts at embryonic stage 10. In the periphery, it labels larval gustatory sensilla in the antennomaxillary complex as well as in the pharynx. GAL4 is also expressed in the CNS in a manner that prefigures expression in adult flies. Most Voila1/1 homozygotes die between second larval instar and early adulthood. Moreover, escapingVoila1/1 larvae do not show gustatory responses to NaCl and sucrose. The simultaneous rescue of normal larval gustation together with adult viability after removal of the transposable PGAL4 element suggests that both these phenotypes are caused by the same inserted element.

• Publication year

  2000

• Venue

  Journal of Neuroscience

• Publication date

  2000-05-01

• Fields of study

  Biology

• Identifiers
  DOI 10.1523/JNEUROSCI.20-09-03425.2000PMCID PMC6773120
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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