Keeping mRNPs in check during assembly and nuclear export

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Nature reviews. Molecular cell biology

• Publication date

  2011-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nrm3119PMID 21602906
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cell structure and dynamics.

  2011cited by this paper
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  2011cited by this paper
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  2010cited by this paper
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  2010cited by this paper
• Control of mRNA Export and Translation Termination by Inositol Hexakisphosphate Requires Specific Interaction with Gle1*

  2010cited by this paper
• Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells

  2010cited by this paper
• The Mitogen-Activated Protein Kinase Slt2 Regulates Nuclear Retention of Non-Heat Shock mRNAs during Heat Shock-Induced Stress

  2010cited by this paper
• A role for TREX components in the release of spliced mRNA from nuclear speckle domains.

  2010cited by this paper
• Post-translational modifications in signal integration

  2010cited by this paper
• RNA processing and export.

  2010cited by this paper
• mRNA Export from Mammalian Cell Nuclei Is Dependent on GANP

  2010cited by this paper
• Connecting the transcription site to the nuclear pore: a multi-tether process that regulates gene expression

  2010cited by this paper
• A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

  2010cited by this paper
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  2010cited by this paper
• Splicing-Dependent RNA Polymerase Pausing in Yeast

  2010cited by this paper
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• Yeast arginine methyltransferase Hmt1p regulates transcription elongation and termination by methylating Npl3p

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• Mechanisms of RNA Degradation by the Eukaryotic Exosome

  2010cited by this paper
• Global analysis of nascent RNA reveals transcriptional pausing in terminal exons.

  2010cited by this paper
• Protein Arginine Methylation Facilitates Cotranscriptional Recruitment of Pre-mRNA Splicing Factors

  2010cited by this paper
• Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1

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• Cdk Phosphorylation of a Nucleoporin Controls Localization of Active Genes through the Cell Cycle

  2010cited by this paper
• Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11.

  2009cited by this paper
• Phosphorylation of the Yeast Rpb1 C-terminal Domain at Serines 2, 5, and 7*

  2009cited by this paper
• The many pathways of RNA degradation.

  2009cited by this paper
• Assembly of an Export-Competent mRNP Is Needed for Efficient Release of the 3′-End Processing Complex after Polyadenylation

  2009cited by this paper
• Specific sequences within arginine–glycine-rich domains affect mRNA-binding protein function

  2009cited by this paper
• mRNA localization: gene expression in the spatial dimension.

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• Ubiquitin-binding domains — from structures to functions

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• The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.

  2009cited by this paper
• An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes

  2009cited by this paper
• Purification of Nuclear Poly(A)-binding Protein Nab2 Reveals Association with the Yeast Transcriptome and a Messenger Ribonucleoprotein Core Structure

  2009cited by this paper
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• mRNA journey to the cytoplasm: attire required

  2008cited by this paper
• THO/Sub2p functions to coordinate 3'-end processing with gene-nuclear pore association.

  2008cited by this paper
• A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast.

  2008cited by this paper
• Functional Significance of the Interaction between the mRNA-binding Protein, Nab2, and the Nuclear Pore-associated Protein, Mlp1, in mRNA Export

  2008cited by this paper
• Cracking the RNA polymerase II CTD code.

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• Sumoylating and desumoylating enzymes at nuclear pores: underpinning their unexpected duties?

  2008cited by this paper
• Regulation of mRNP dynamics along the export pathway

  2008cited by this paper
• The mRNA export factor Gle1 and inositol hexakisphosphate regulate distinct stages of translation.

  2008cited by this paper
• Splicing promotes rapid and efficient mRNA export in mammalian cells

  2008cited by this paper
• Structure of the N-Terminal Mlp1-Binding Domain of the Saccharomyces cerevisiae mRNA-Binding Protein, Nab2

  2008cited by this paper
• Quality control of mRNP in the nucleus

  2008cited by this paper
• Nuclear mRNA surveillance in THO/sub2 mutants is triggered by inefficient polyadenylation.

  2008cited by this paper
• Autoregulation of Npl3, a Yeast SR Protein, Requires a Novel Downstream Region and Serine Phosphorylation

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• Unphosphorylated SR-Like Protein Npl3 Stimulates RNA Polymerase II Elongation

  2008cited by this paper
• Why cells move messages: the biological functions of mRNA localization.

  2007cited by this paper
• SAGA and a novel Drosophila export complex anchor efficient transcription and mRNA export to NPC

  2007cited by this paper
• Exporting RNA from the nucleus to the cytoplasm

  2007cited by this paper
• A nuclear envelope protein linking nuclear pore basket assembly, SUMO protease regulation, and mRNA surveillance

  2007cited by this paper
• Following Temperature Stress, Export of Heat Shock mRNA Occurs Efficiently in Cells with Mutations in Genes Normally Important for mRNA Export

  2007cited by this paper
• The DEAD-box protein Dbp5 controls mRNA export by triggering specific RNA:protein remodeling events.

  2007cited by this paper
• Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export

  2006cited by this paper
• Cotranscriptional Recruitment to the mRNA Export Receptor Mex67p Contributes to Nuclear Pore Anchoring of Activated Genes

  2006cited by this paper
• Human mRNA export machinery recruited to the 5' end of mRNA.

  2006cited by this paper
• Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export

  2006cited by this paper
• Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription

  2006cited by this paper
• Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factors.

  2005cited by this paper
• Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex.

  2005cited by this paper
• SRprises along a messenger's journey.

  2005cited by this paper
• Defining the SUMO-modified Proteome by Multiple Approaches in Saccharomyces cerevisiae*

  2005cited by this paper
• Recruitment of the human TREX complex to mRNA during splicing.

  2005cited by this paper
• Functional specificity of shuttling hnRNPs revealed by genome-wide analysis of their RNA binding profiles.

  2005cited by this paper
• Npl3 is an antagonist of mRNA 3′ end formation by RNA polymerase II

  2005cited by this paper
• A New Yeast Poly(A) Polymerase Complex Involved in RNA Quality Control

  2005cited by this paper
• RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.

  2005cited by this paper
• The DEAD-box protein Dbp5p is required to dissociate Mex67p from exported mRNPs at the nuclear rim.

  2005cited by this paper
• Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeast.

  2005cited by this paper
• Arginine Methylation of Yeast mRNA-binding Protein Npl3 Directly Affects Its Function, Nuclear Export, and Intranuclear Protein Interactions*

  2005cited by this paper
• Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export

  2005cited by this paper
• Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase.

  2005cited by this paper
• Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors.

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
• Yeast Shuttling SR Proteins Npl3p, Gbp2p, and Hrb1p Are Part of the Translating mRNPs, and Npl3p Can Function as a Translational Repressor

  2004cited by this paper
• The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA.

  2004cited by this paper
• The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export

  2003cited by this paper
• Nab2p Is Required for Poly(A) RNA Export in Saccharomyces cerevisiae and Is Regulated by Arginine Methylation via Hmt1p*

  2002cited by this paper
• TREX is a conserved complex coupling transcription with messenger RNA export

  2002cited by this paper
• Stable mRNP Formation and Export Require Cotranscriptional Recruitment of the mRNA Export Factors Yra1p and Sub2p by Hpr1p

  2002cited by this paper
• What messenger RNA capping tells us about eukaryotic evolution

  2002cited by this paper
• Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation.

  2001cited by this paper
• A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

  2000cited by this paper
• A putative ubiquitin ligase required for efficient mRNA export differentially affects hnRNP transport.

  2000cited by this paper
• Biochemical and Functional Characterization of Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinases*

  2000cited by this paper
• Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export.

  1999cited by this paper
• Arginine methylation facilitates the nuclear export of hnRNP proteins.

  1998cited by this paper
• The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.

  1996cited by this paper
• A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins

  1996cited by this paper
• The essential yeast RNA binding protein Np13p is methylated.

  1996cited by this paper
• Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography.

  1992cited by this paper

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