Multifactorial Biological Modulation of Warm Ischemia Reperfusion Injury in Liver Transplantation From Non–Heart-Beating Donors Eliminates Primary Nonfunction and Reduces Bile Salt Toxicity

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Annals of Surgery

• Publication date

  2009-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/SLA.0b013e3181bdd787PMID 19826248
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation.

  2009cited by this paper
• Increased serum phospholipase A2 activity after non-heart-beating donor liver transplantation and association with ischemia-reperfusion injury.

  2009cited by this paper
• Methylprednisolone Therapy in Deceased Donors Reduces Inflammation in the Donor Liver and Improves Outcome After Liver Transplantation: A Prospective Randomized Controlled Trial

  2008cited by this paper
• Heme Oxygenase‐1 Genotype of the Donor Is Associated With Graft Survival After Liver Transplantation

  2008cited by this paper
• The Role of Bile Salt Toxicity in the Pathogenesis of Bile Duct Injury After Non-Heart-Beating Porcine Liver Transplantation

  2008influential reference
• Machine Perfusion for ‘Marginal’ Liver Grafts

  2008cited by this paper
• Impact of innate and adaptive immunity on rejection and tolerance.

  2008cited by this paper
• Ischaemic preconditioning for liver transplantation.

  2008cited by this paper
• The extent of vacuolation in non–heart‐beating porcine donor liver grafts prior to transplantation predicts their viability

  2008cited by this paper
• Report of the Paris consensus meeting on expanded criteria donors in liver transplantation

  2008cited by this paper
• Clinical Trial of the Pan‐Caspase Inhibitor, IDN‐6556, in Human Liver Preservation Injury

  2007cited by this paper
• Primary graft nonfunction and Kupffer cell activation after liver transplantation from non‐heart‐beating donors in pigs

  2007influential reference
• Non‐heart beating organ donation: overview and future perspectives

  2007cited by this paper
• Pathomechanisms of ischemia-reperfusion injury as the basis for novel preventive strategies: is it time for the introduction of pleiotropic compounds?

  2007cited by this paper
• The response of the hepatocyte to ischemia

  2007cited by this paper
• Thymoglobulin and ischemia reperfusion injury in kidney and liver transplantation.

  2007cited by this paper
• Past and future approaches to ischemia-reperfusion lesion associated with liver transplantation.

  2006cited by this paper
• Bile salt toxicity aggravates cold ischemic injury of bile ducts after liver transplantation in Mdr2+/− mice

  2006cited by this paper
• The role of glycine in hepatic ischemia-reperfusion injury.

  2006cited by this paper
• A single solution for multiple organ procurement and preservation

  2005cited by this paper
• Graft Failure: Etiology, Recognition, and Treatment

  2005cited by this paper
• The contemporary role of antioxidant therapy in attenuating liver ischemia‐reperfusion injury: A review

  2005cited by this paper
• Livers from Non–Heart-Beating Donors Tolerate Short Periods of Warm Ischemia

  2005influential reference
• Attenuation of graft injury in porcine liver transplantation from non-heart beating donor by FR167653.

  2005cited by this paper
• Reduction of circulating redox-active iron by apotransferrin protects against renal ischemia-reperfusion injury1

  2004cited by this paper
• Glutathione Protects the Rat Liver Against Reperfusion Injury After Prolonged Warm Ischemia

  2004cited by this paper
• Rusty notions of cell injury.

  2004cited by this paper
• The Role of MAP Kinases in Trauma and Ischemia–Reperfusion

  2004cited by this paper
• Non-heart beating donors.

  2004cited by this paper
• Rapid increase of bile salt secretion is associated with bile duct injury after human liver transplantation.

  2004cited by this paper
• Intravenous administration of glutathione protects parenchymal and non-parenchymal liver cells against reperfusion injury following rat liver transplantation.

  2004cited by this paper
• Survival Following Liver Transplantation From Non-Heart-Beating Donors

  2004cited by this paper
• Exogenous alpha-1-Acid Glycoprotein Protects against Renal Ischemia-Reperfusion Injury by Inhibition of Inflammation and Apoptosis

  2004cited by this paper
• L-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent

  2003cited by this paper
• How to improve the quality of kidneys from non-heart-beating donors: a randomised controlled trial of thrombolysis in non–heart-beating donors

  2003cited by this paper
• Labile plasma iron in iron overload: redox activity and susceptibility to chelation.

  2003cited by this paper
• Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties.

  2003cited by this paper
• Improvement of microvascular graft equilibration and preservation in non-heart-beating donors by warm preflush with streptokinase1

  2003cited by this paper
• Protective strategies against ischemic injury of the liver.

  2003cited by this paper
• Successful liver transplantation from agonal non-heart-beating donors in pigs

  2003cited by this paper
• Advantages of normothermic perfusion over cold storage in liver preservation

  2002cited by this paper
• Influence of marginal donors on liver preservation injury

  2002cited by this paper
• Gene therapy and solid-organ transplantation.

  2002cited by this paper
• Intramuscular Administration of Very High Dose of a-Tocopherol Protects Liver from Severe Ischemia/Reperfusion Injury

  2002cited by this paper
• Extended experience with glycine for prevention of reperfusion injury after human liver transplantation.

  2002influential reference
• P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver.

  2002cited by this paper
• FIBRINOLYTIC PREFLUSH UPON LIVER RETRIEVAL FROM NON–HEART BEATING DONORS TO ENHANCE POSTPRESERVATION VIABILITY AND ENERGETIC RECOVERY UPON REPERFUSION

  2001cited by this paper
• Trolox C ameliorates hepatic drug metabolizing dysfunction after ischemia/reperfusion.

  2001influential reference
• Simplified technique of orthotopic liver transplantation in pigs.

  2001cited by this paper
• Type of donor aortic preservation solution and not cold ischemia time is a major determinant of biliary strictures after liver transplantation

  2001cited by this paper
• Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia

  2001cited by this paper
• Warm preflush with streptokinase improves microvascular procurement and tissue integrity in liver graft retrieval from non-heart-beating donors.

  2000cited by this paper
• PHARMACOLOGIC GRAFT PROTECTION WITHOUT DONOR PRETREATMENT IN LIVER TRANSPLANTATION FROM NON-HEART-BEATING DONORS1

  2000cited by this paper
• Glycine Prevents Apoptosis of Rat Sinusoidal Endothelial Cells Caused by Deprivation of Vascular Endothelial Growth Factor

  2000cited by this paper
• Preconditioning of donor livers with prostaglandin I2 before retrieval decreases hepatocellular ischemia-reperfusion injury.

  1999cited by this paper
• Intravenous glycine improves survival in rat liver transplantation.

  1999cited by this paper
• Intravenous glycine improves survival in rat liver transplantation.

  1999cited by this paper
• High-level Constitutive Expression of α1-acid Glycoprotein and Lack of Protection Against Tumor Necrosis Factor-induced Lethal Shock in Transgenic Mice

  1998cited by this paper
• Liver transplantation from non-heart beating donors in rats: influence of viscosity and temperature of initial flushing solutions on graft function.

  1997cited by this paper
• Influence of ischemia-reperfusion injury on rejection after liver transplantation.

  1997cited by this paper
• Pilot study: Carolina Rinse Solution improves graft function after orthotopic liver transplantation in humans.

  1997cited by this paper
• Protection by Carolina rinse solution, acidotic pH, and glycine against lethal reperfusion injury to sinusoidal endothelial cells of rat livers stored for transplantation.

  1996cited by this paper
• Evidence of preservation injury to bile ducts by bile salts in the pig and its prevention by infusions of hydrophilic bile salts

  1995cited by this paper
• Transplantation of the Liver

  1989cited by this paper
• Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile.

  1978cited by this paper

• Hepatic ischemia reperfusion injury: Underlying mechanisms and concepts in liver surgery and liver transplantation.

  2025cites this paper
• Effect of a Combined Drug Approach on the Severity of Ischemia-Reperfusion Injury During Liver Transplant

  2023cites this paper
• Cell therapy during machine perfusion

  2020cites this paper
• Renal disease in the allograft recipient.

  2020cites this paper
• Heterogeneity of Bile Duct Management in the Development of Ischemic Cholangiopathy After Liver Transplantation: Results of a European Liver and Intestine Transplant Association Survey.

  2019cites this paper
• The Protective Effects of Carbon Monoxide Against Hepatic Warm Ischemia–Reperfusion Injury in MHC-Inbred Miniature Swine

  2019cites this paper
• DCD Liver Transplant: a Meta-review of the Evidence and Current Optimization Strategies

  2018cites this paper
• Emerging Innovations in Liver Preservation and Resuscitation.

  2018cites this paper
• S‐Adenosylmethionine attenuates bile duct early warm ischemia reperfusion injury after rat liver transplantation

  2018cites this paper
• Organ preservation: from the past to the future

  2018cites this paper
• Advancing Transplantation: New Questions, New Possibilities in Kidney and Liver Transplantation

  2017cites this paper
• Liver ex situ machine perfusion preservation: A review of the methodology and results of large animal studies and clinical trials

  2017cites this paper
• Therapeutic use of transferrin to modulate anemia and conditions of iron toxicity.

  2017cites this paper
• Donation After Circulatory Death for Liver Transplantation: A Meta-Analysis on the Location of Life Support Withdrawal Affecting Outcomes

  2016cites this paper
• Liver graft preconditioning, preservation and reconditioning.

  2016cites this paper
• A multidrug cocktail approach attenuates ischemic-type biliary lesions in liver transplantation from non-heart-beating donors.

  2016cites this paper
• A Systematic Review of Pharmacological Treatment Options Used to Reduce Ischemia Reperfusion Injury in Rat Liver Transplantation

  2015cites this paper
• Non-transferrin-bound iron in hematopoietic stem cell transplantation

  2015cites this paper
• Current status and recent advances in liver transplant using organs donated after cardiac death.

  2015cites this paper
• Investigating the role of endothelial nitric oxide synthase in liver ischaemia reperfusion injury and direct ischaemic preconditioning using a transgenic double knockout model of endothelial nitric oxide synthase

  2014cites this paper
• Impact of Recombinant Globular Adiponectin on Early Warm Ischemia-Reperfusion Injury in Rat Bile Duct after Liver Transplantation

  2014cites this paper
• DCD for Liver Transplantation

  2014cites this paper
• Assessing warm ischemic injury of pig livers at hypothermic machine perfusion.

  2014cites this paper
• Organomatics and organometrics: Novel platforms for long-term whole-organ culture.

  2014cites this paper
• Best temperature for static liver graft storage is 1°C.

  2013cites this paper
• Protective Effect of Gadolinium Chloride on Early Warm Ischemia/Reperfusion Injury in Rat Bile Duct during Liver Transplantation

  2013cites this paper
• Resuscitation of Ischemic Donor Livers with Normothermic Machine Perfusion: A Metabolic Flux Analysis of Treatment in Rats

  2013cites this paper
• Challenges in machine perfusion preservation for liver grafts from donation after circulatory death

  2013cites this paper
• The Differential Tissue Expression of Inflammatory, Oxidative Stress, and Apoptosis Markers in Human Uncontrolled Non-Heart-Beating Donors

  2013cites this paper
• Machine perfusion in organ transplantation: a tool for ex-vivo graft conditioning with mesenchymal stem cells?

  2013cites this paper
• Protective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts.

  2013cites this paper
• Is extracorporeal hypothermic machine perfusion of the liver better than the ‘good old icebox’?

  2012cites this paper
• Improving the function of liver grafts exposed to warm ischemia by the leuven drug protocol: Exploring the molecular basis by microarray

  2012cites this paper
• Liver transplantation using Donation after Cardiac Death donors.

  2012cites this paper
• Extending Donor Pool with Donation after Cardiac Death in Kidney and Liver Transplantation:What is the Price to Pay?

  2012cites this paper
• Donation after cardio-circulatory death liver transplantation.

  2012cites this paper
• Trends in liver transplantation 2011.

  2012cites this paper
• Outcomes of liver transplantations using donations after circulatory death: a single-center experience.

  2012cites this paper
• Circulatory Injury in Liver Transplantation

  2011cites this paper
• Differential gene expression profile of porcine livers subjected to warm ischemia alone.

  2011cites this paper
• Current status and recent advances of liver transplantation from donation after cardiac death.

  2011cites this paper
• Deceased donor liver transplantation

  2010cites this paper
• La perfusión normotérmica “ex-situ” como continuación de la “recirculación normotérmica” en la obtención de injertos hepáticos procedentes de donantes a corazón parado

  2010cites this paper
• Pharmacological strategies against cold ischemia reperfusion injury

  2010cites this paper
• Biological modulation of liver ischemia–reperfusion injury

  2010cites this paper
• Current World Literature

  2010cites this paper
• Use of Tissue Plasminogen Activator in Liver Transplantation from Donation After Cardiac Death Donors

  2010cites this paper
• Biological modulation of renal ischemia–reperfusion injury

  2010cites this paper
• Time to think out of the (ice) box.

  2010cites this paper
• , preservation and reconditioning

  year unknowncites this paper