THE EFFECT OF P-CHLOROMERCURIBENZOATE ON AMOEBOID MOVEMENT, FLAGELLAR MOVEMENT AND GLIDING MOVEMENT

1. The effect of p-chloromercuribenzoate (PCMB), a specific sulfhydryl reagent, upon several types of cellular motion—amoeboid movement, flagellar movement and gliding movement—was studied.2. The effect of PCMB on the motions of different types is more or less identical: First, motion becomes sluggish; this is then followed by complete cessation at some particular concentration. Second, motion is restored completely or partially through subsequent application of cysteine in concentrations higher than those of the PCMB previously applied. Third, when the reactivity of PCMB upon -SH groups has been eliminated with cysteine in advance, PCMB exerts no effect the cellular motion.3. From the fact that PCMB is bound to -SH groups with high specificity, it is reasonable to conclude that the cessation and recovery of the cellular motion are closely related to the blocking and liberation of -SH groups.

• Publication year

  1963

• Venue

  The Biological Bulletin

• Publication date

  1963-04-01

• Fields of study

  Biology, Chemistry

• Identifiers
  DOI 10.2307/1539487
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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