Dynamic simulation of the human red blood cell metabolic network

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Bioinform.

• Publication date

  2001-03-01

• Fields of study

  Biology, Mathematics, Medicine, Computer Science

• Identifiers
  DOI 10.1093/BIOINFORMATICS/17.3.286PMID 11294796
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: computer simulation and metabolic control analysis.

  1999cited by this paper
• A thermodynamic model of hemoglobin suitable for physiological applications.

  1990cited by this paper
• Metabolic dynamics in the human red cell. Part I--A comprehensive kinetic model.

  1989cited by this paper
• Mathematica--A System for Doing Mathematics by Computer.

  1989cited by this paper
• Application of progress curve analysis to in situ enzyme kinetics using 1H NMR spectroscopy.

  1986cited by this paper
• A kinetic model for the interaction of energy metabolism and osmotic states of human erythrocytes. Analysis of the stationary "in vivo" state and of time dependent variations under blood preservation conditions.

  1985cited by this paper
• Mathematical modelling of metabolic pathways affected by an enzyme deficiency. A mathematical model of glycolysis in normal and pyruvate-kinase-deficient red blood cells.

  1985cited by this paper
• Regulation of glycolysis in human erythrocytes. The mechanism of ATP concentration stabilization.

  1981cited by this paper
• Biochemical mechanisms of glucose-6-phosphate dehydrogenase deficiency.

  1978cited by this paper
• A mathematical model for the influence of anionic effectors on the phosphofructokinase from rat erythrocytes.

  1977cited by this paper
• Glutathione Reductase from Human Erythrocytes

  1976influential reference
• Glutathione reductase from human erythrocytes. Catalytic properties and aggregation.

  1976cited by this paper
• [On the effect of glycolytic intermediary products on the 2,3-PGase activity of red blood cells].

  1965cited by this paper

• Simulasi Blood Type Inheritance dengan Pemrograman Software Wolfram

  2022cites this paper
• Modeling and analysis of flux distribution and bioproduct formation in Synechocystis sp. PCC 6803 using a new genome-scale metabolic reconstruction

  2017cites this paper
• Applications of NMR spectroscopy to systems biochemistry.

  2016cites this paper
• An extension of fuzzy topological approach for comparison of genetic sequences

  2015cites this paper
• Modeling metabolism: a window toward a comprehensive interpretation of networks in cancer.

  2015cites this paper
• METABOLIC FLUX IS A DETERMINANT OF THE EVOLUTIONARY RATES OF ENZYME‐ENCODING GENES

  2014cites this paper
• Genome-Scale Modeling of Tissue and Cancer Metabolism

  2014cites this paper
• Syzygium cumini is more effective in preventing the increase of erythrocytic ADA activity than phenolic compounds under hyperglycemic conditions in vitro

  2014cites this paper
• Probabilistic Reconstruction and Comparative Systems Biology of Microbial Metabolism

  2013cites this paper
• Models of Ion Transport in Mammalian Cells

  2013cites this paper
• Red blood cell metabolism under prolonged anaerobic storage.

  2013cites this paper
• Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective

  2013cites this paper
• Kinetic Modelling of GlmU Reactions – Prioritization of Reaction for Therapeutic Application

  2012cites this paper
• Clinical metabolomics: the next stage of clinical biochemistry.

  2012cites this paper
• Modeling metabolic networks for mammalian cell systems: general considerations, modeling strategies, and available tools.

  2012cites this paper
• Reconstruction And Analysis Of The Molecular Programs Involved In Deciding Mammalian Cell Fate

  2012cites this paper
• Reaction Networks as Systems for Resource Allocation: A Variational Principle for Their Non-Equilibrium Steady States

  2012cites this paper
• Genomics and Systems Biology of Mammalian Cell Culture

  2012cites this paper
• Central carbon metabolism of Plasmodium parasites.

  2011cites this paper
• A dynamic state metabolic journey: from mass spectrometry to network analysis via estimation of kinetic parameters

  2011cites this paper
• iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states

  2011cites this paper
• Cell Growth Dynamics

  2011cites this paper
• Modeling formalisms in Systems Biology

  2011cites this paper
• Computational Approaches in Metabolic Engineering

  2011cites this paper
• Flux Measurement Selection in Metabolic Networks

  2011cites this paper
• Genome-scale metabolic models of Saccharomyces cerevisiae.

  2011cites this paper
• The solution space of metabolic networks: Producibility, robustness and fluctuations

  2010cites this paper
• Mass action stoichiometric simulation models: incorporating kinetics and regulation into stoichiometric models.

  2010cites this paper
• A study of entropy/clarity of genetic sequences using metric spaces and fuzzy sets.

  2010cites this paper
• A Metabolic Model of Human Erythrocytes: Practical Application of the E-Cell Simulation Environment

  2010cites this paper
• Computational Challenges in Systems Biology

  2010cites this paper
• Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model

  2010cites this paper
• Project-Team Symbiose SYstèmes et Modèles BIOlogiques, BIOinformatique et SEquences

  2010cites this paper
• eview entral carbon metabolism of Plasmodium parasites

  2010cites this paper
• Hybrid dynamic modeling of Escherichia coli central metabolic network combining Michaelis-Menten and approximate kinetic equations

  2010cites this paper
• A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis

  2009cites this paper
• Filling Kinetic Gaps: Dynamic Modeling of Metabolism Where Detailed Kinetic Information Is Lacking

  2009influential citation
• Nutritional Systems Biology Modeling: From Molecular Mechanisms to Physiology

  2009cites this paper
• Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes

  2009cites this paper
• Predicting metabolic biomarkers of human inborn errors of metabolism

  2009cites this paper
• Biological Data Integration and Model Building

  2009cites this paper
• Selective gene amplification for high-throughput sequencing.

  2009cites this paper
• Reconstruction of dynamic metabolic networks : challenges, limitations and alternative solutions

  2009cites this paper
• The Synthesizing Capacity of Metabolic Networks

  2008cites this paper
• Crossing borders between biology and data analysis

  2008cites this paper
• Nonparametric Clustering of Functional Data

  2008cites this paper
• A comparative analysis of kinetic models of erythrocyte glycolysis.

  2008cites this paper
• Integrating thermodynamics-based modeling and quantitative experimental data for studying microbial metabolism

  2008cites this paper
• Computational analysis of metabolic networks

  2008cites this paper
• Formulating genome-scale kinetic models in the post-genome era

  2008cites this paper
• Metabolic Organization in Plants: A Challenge for the Metabolic Engineer

  2008cites this paper
• Discovering Regulators of the Drosophila Cardiac Hypoxia Response Using Automated Phenotyping Technology

  2008cites this paper
• Top-Down Analysis of Temporal Hierarchy in Biochemical Reaction Networks

  2008cites this paper
• Detailed Enzyme Kinetics in Terms of Biochemical Species: Study of Citrate Synthase

  2008cites this paper
• Biochemical and statistical network models for systems biology.

  2007cites this paper
• Project-Team symbiose SYstèmes et Modèles BIOlogiques, BIOinformatique et SEquences

  2007cites this paper
• METABOLIC ENGINEERING OF EMBRYONIC STEM CELL DIFFERENTIATION INTO HEPATOCYTES By

  2007cites this paper
• Reconstruction of Metabolic Networks from High‐Throughput Metabolite Profiling Data

  2007influential citation
• Network-level analysis of metabolic regulation in the human red blood cell using random sampling and singular value decomposition

  2006cites this paper
• Systems biology of the human red blood cell.

  2006cites this paper
• Analysis of enzymopathies in the human red blood cells by constraint-based stoichiometric modeling approaches

  2006cites this paper
• Fuzzy polynucleotide spaces and metrics

  2006cites this paper
• k-Cone analysis: determining all candidate values for kinetic parameters on a network scale.

  2005influential citation
• Glycolysis and Flux Control

  2005cites this paper
• Cell Engineering

  2005cites this paper
• Hierarchical petri nets for modeling metabolic phenotype in prokaryotes

  2005cites this paper
• Adenine and adenosine salvage pathways in erythrocytes and the role of S‐adenosylhomocysteine hydrolase

  2005cites this paper
• Theoretical Biology and Medical Modelling Open Access Dynamic Simulation of Red Blood Cell Metabolism and Its Application to the Analysis of a Pathological Condition

  2005cites this paper
• Biochemical Modelling Tools and Applications to Metabolic Engineering

  2005cites this paper
• Project-Team symbiose SYstèmes et Modèles BIOlogiques, BIOinformatique et SEquences

  2005influential citation
• Microbial Functional Genomics: Zhou/Microbial Functional Genomics

  2005cites this paper
• Finding Feasible Pathways in Metabolic Networks

  2005cites this paper
• Uniform sampling of steady-state flux spaces: means to design experiments and to interpret enzymopathies.

  2004influential citation
• Monte Carlo sampling can be used to determine the size and shape of the steady-state flux space.

  2004influential citation
• The principle of flux minimization and its application to estimate stationary fluxes in metabolic networks.

  2004cites this paper
• Computational Design of Reduced Metabolic Networks

  2004cites this paper
• The Computational Integrated Myocyte: A View into the Virtual Heart

  2004cites this paper
• Inferring dynamic properties of biochemical reaction networks from structural knowledge.

  2004cites this paper
• Analyzing the Biology on the System Level

  2004cites this paper
• A Systems View of Cell Death

  2004cites this paper
• Network-based analysis of metabolic regulation in the human red blood cell.

  2003cites this paper
• Reconstructing metabolic flux vectors from extreme pathways: defining the α-spectrum

  2003cites this paper
• Identifying constraints that govern cell behavior: a key to converting conceptual to computational models in biology?

  2003cites this paper
• An Exact Formula for the Number of Alignments Between Two DNA Sequences

  2003cites this paper
• Reconstructing metabolic flux vectors from extreme pathways: defining the alpha-spectrum.

  2003cites this paper
• Towards automated derivation of biological pathways using high-throughput biological data

  2003cites this paper
• From Annotated Genomes to Metabolic Flux Models and Kinetic Parameter Fitting

  2003cites this paper
• Metabolic pathways in the post-genome era.

  2003cites this paper
• Genome-scale microbial in silico models: the constraints-based approach.

  2003cites this paper
• The complexity of complexes in signal transduction

  2003cites this paper
• A metric space to study differences between polynucleotides

  2003cites this paper
• The fuzzy polynucleotide space: basic properties

  2003cites this paper
• Computational systems biology

  2002cites this paper
• Description and analysis of metabolic connectivity and dynamics in the human red blood cell.

  2002cites this paper
• Analysis of optimality in natural and perturbed metabolic networks

  2002cites this paper
• Suitability and Utility of Computational Analysis Tools: Characterization of Erythrocyte Parameter Variation

  2002cites this paper
• Extreme pathway analysis of human red blood cell metabolism.

  2002cites this paper
• In silico model-driven assessment of the effects of single nucleotide polymorphisms (SNPs) on human red blood cell metabolism.

  2002cites this paper
• In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data

  2001cites this paper