Local, three-dimensional strain measurements within largely deformed extracellular matrix constructs.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Biomechanical Engineering

• Publication date

  2004-12-01

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1115/1.1824127PMID 15796328
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Simultaneous Mechanical Loading and Confocal Reflection Microscopy for Three-Dimensional Microbiomechanical Analysis of Biomaterials and Tissue Constructs

  2003cited by this paper
• Spatial and temporal traction response in human airway smooth muscle cells.

  2002cited by this paper
• Particle Image Velocimetry: A Practical Guide

  2002cited by this paper
• Myofibroblasts and mechano-regulation of connective tissue remodelling

  2002cited by this paper
• Microscope-based techniques to study cell adhesion and migration

  2002cited by this paper
• Tensile mechanical properties of three-dimensional type I collagen extracellular matrices with varied microstructure.

  2002cited by this paper
• Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus.

  2002cited by this paper
• Predicting local cell deformations in engineered tissue constructs: a multilevel finite element approach.

  2002cited by this paper
• An automated approach for direct measurement of two-dimensional strain distributions within articular cartilage under unconfined compression.

  2002cited by this paper
• Digital volume correlation including rotational degrees of freedom during minimization

  2002cited by this paper
• Three-dimensional imaging of extracellular matrix and extracellular matrix-cell interactions.

  2001cited by this paper
• Fibroblasts in Mechanically Stressed Collagen Lattices Assume a “Synthetic” Phenotype*

  2001cited by this paper
• Coupled macroscopic and microscopic scale modeling of fibrillar tissues and tissue equivalents.

  2001cited by this paper
• The mechanical environment of the chondrocyte: a biphasic finite element model of cell-matrix interactions in articular cartilage.

  2000cited by this paper
• Stress-relaxation and contraction of a collagen matrix induces expression of TGF-β and triggers apoptosis in dermal fibroblasts

  2000cited by this paper
• Time-lapse confocal reflection microscopy of collagen fibrillogenesis and extracellular matrix assembly in vitro.

  2000cited by this paper
• Stress-relaxation and contraction of a collagen matrix induces expression of TGF-beta and triggers apoptosis in dermal fibroblasts.

  2000cited by this paper
• Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels.

  2000cited by this paper
• Mechanical loading regulates protease production by fibroblasts in three‐dimensional collagen substrates

  2000cited by this paper
• Techniques for mechanical stimulation of cells in vitro: a review.

  2000cited by this paper
• A cell-based constitutive relation for bio-artificial tissues.

  2000cited by this paper
• High resolution detection of mechanical forces exerted by locomoting fibroblasts on the substrate.

  1999cited by this paper
• Stresses at the cell-to-substrate interface during locomotion of fibroblasts.

  1999cited by this paper
• Digital volume correlation: Three-dimensional strain mapping using X-ray tomography

  1999cited by this paper
• A microstructural model for the tensile constitutive and failure behavior of soft skeletal connective tissues.

  1998cited by this paper
• Effect of precise mechanical loading on fibroblast populated collagen lattices: morphological changes.

  1998cited by this paper
• A method to quantify the fiber kinematics of planar tissues under biaxial stretch.

  1997cited by this paper
• An in vitro force measurement assay to study the early mechanical interaction between corneal fibroblasts and collagen matrix.

  1997cited by this paper
• Cell locomotion and focal adhesions are regulated by substrate flexibility.

  1997cited by this paper
• An anisotropic biphasic theory of tissue-equivalent mechanics: the interplay among cell traction, fibrillar network deformation, fibril alignment, and cell contact guidance.

  1997cited by this paper
• A finite element solution for the anisotropic biphasic theory of tissue-equivalent mechanics: the effect of contact guidance on isometric cell traction measurement.

  1997cited by this paper
• High-temperature deformation measurements using digital-image correlation

  1996cited by this paper
• Chondrocyte deformation and local tissue strain in articular cartilage: A confocal microscopy study

  1995cited by this paper
• Mechanical Load and Polypeptide Growth Factors Stimulate Cardiac Fibroblast Activity

  1995cited by this paper
• Biphasic Theory and In Vitro Assays of Cell-Fibril Mechanical Interactions in Tissue-Equivalent Gels

  1994cited by this paper
• Traction forces generated by locomoting keratocytes

  1994cited by this paper
• Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway

  1994cited by this paper
• Volume and surface area measurement of viable chondrocytes in situ using geometric modelling of serial confocal sections

  1994cited by this paper
• Optimal image correlation in experimental mechanics

  1994cited by this paper
• Tenascin-C expression by fibroblasts is elevated in stressed collagen gels

  1994cited by this paper
• Stress, Strain, Pressure and Flow Fields in Articular Cartilage and Chondrocytes

  1994cited by this paper
• Pretranslational regulation of extracellular matrix macromolecules and collagenase expression in fibroblasts by mechanical forces.

  1992cited by this paper
• Numerical Methods for Engineers and Scientists

  1992cited by this paper
• Collagen expression in mechanically stimulated cardiac fibroblasts.

  1991cited by this paper
• Handbook of Biological Confocal Microscopy

  1990cited by this paper
• Estimation of stress intensity factor by digital image correlation

  1987cited by this paper
• A Finite Deformation Theory for Nonlinearly Permeable Soft Hydrated Biological Tissues

  1986cited by this paper
• Applications of digital-image-correlation techniques to experimental mechanics

  1985cited by this paper
• Biomechanics — Mechanical properties of living tissue

  1982cited by this paper
• Biomechanics: Mechanical Properties of Living Tissues

  1981cited by this paper
• Silicone rubber substrata: a new wrinkle in the study of cell locomotion.

  1980cited by this paper

• Model-driven digital volume correlation: A step forward in experimental analyses of metamaterial deformations

  2025cites this paper
• Measuring full-field strain of the muscle-tendon junction using confocal microscopy combined with digital volume correlation.

  2025cites this paper
• Digital volume correlation for the characterization of musculoskeletal tissues: Current challenges and future developments

  2022cites this paper
• Quantification of Errors in Applying DIC to Fiber Networks Imaged by Confocal Microscopy

  2022cites this paper
• Three-Dimensional Quantification of Collagen Microstructure During Tensile Mechanical Loading of Skin

  2021cites this paper
• From local to global matrix organization by fibroblasts: a 4D laser-assisted bioprinting approach

  2021cites this paper
• An accurate and sample hybrid strategy for digital volume correlation

  2020cites this paper
• Three‐dimensional static optical coherence elastography based on inverse compositional Gauss‐Newton digital volume correlation

  2019cites this paper
• Integrating structural heterogeneity, fiber orientation, and recruitment in multiscale ECM mechanics.

  2019cites this paper
• In situ characterization of nanoscale strains in loaded whole joints via synchrotron X-ray tomography

  2019cites this paper
• Multi-scale Mechanics of Collagen Networks: Biomechanical Basis of Matrix Remodeling in Cancer

  2019cites this paper
• Quantification of focal adhesion dynamics of cell movement based on cell-induced collagen matrix deformation using second-harmonic generation microscopy

  2018cites this paper
• Incremental digital volume correlation method with nearest subvolume offset: An accurate and simple approach for large deformation measurement

  2018cites this paper
• Inverse poroelasticity as a fundamental mechanism in biomechanics and mechanobiology

  2017cites this paper
• The pressure-induced deformation response of the human lamina cribrosa: Analysis of regional variations.

  2017cites this paper
• Quantitative image analysis for investigating cell-matrix interactions

  2017cites this paper
• Cell-matrix mechanical interaction in electrospun polymeric scaffolds for tissue engineering: Implications for scaffold design and performance.

  2017cites this paper
• COLLAGEN PREPARATION AND METHOD OF SOLATION

  2017cites this paper
• Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices

  2017cites this paper
• Research progress in digital volume correlation method

  2017cites this paper
• Finding the Links between Knee Injuries and Osteoarthritis

  2016cites this paper
• Phase-Contrast Micro-Computed Tomography Measurements of the Intraocular Pressure-Induced Deformation of the Porcine Lamina Cribrosa

  2016cites this paper
• Phase-Contrast Micro-Computed Tomography Measurements of the Intraocular Pressure-Induced Deformation of the Porcine Lamina Cribrosa.

  2016cites this paper
• multidimensional perspective and fundamental fibroblast behavior: a composition regulates local cell-ECM biomechanics Extracellular matrix (ECM) microstructural

  2015cites this paper
• A Fast Iterative Digital Volume Correlation Algorithm for Large Deformations

  2015cites this paper
• Inferring intra-cellular mechanics using geometric metamorphosis: A preliminary study

  2015cites this paper
• Quantifying cell-induced matrix deformation in three dimensions based on imaging matrix fibers.

  2015cites this paper
• Collagen–Cell Interactions in Three- Dimensional Microenvironments

  2014cites this paper
• Learning from Tissue Equivalents: Biomechanics and Mechanobiology

  2014cites this paper
• Application of the digital volume correlation technique for the measurement of displacement and strain fields in bone: a literature review.

  2014cites this paper
• A Fast Iterative Digital Volume Correlation Algorithm for Large Deformations

  2014influential citation
• Image-based Characterization of the Mechanical Behaviour of Healthy and Metastatically-involved Vertebrae

  2014cites this paper
• Dynamics of Cell–Matrix Mechanical Interactions in Three Dimensions

  2013cites this paper
• Quantifying traction stresses in adherent cells.

  2012cites this paper
• Multiscale strain analysis of tissue equivalents using a custom-designed biaxial testing device.

  2012cites this paper
• Mechanobiology of tumor invasion: engineering meets oncology.

  2012cites this paper
• A quantitative study of the three dimensional microstructure of articular cartilage to assess its physical integrity

  2012cites this paper
• Mechanical restrictions on biological responses by adherent cells within collagen gels.

  2012influential citation
• Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture.

  2012cites this paper
• Three-Dimensional Traction Force Microscopy: A New Tool for Quantifying Cell-Matrix Interactions

  2011cites this paper
• Engineering of a periodontal ligament construct: cell and fibre alignment induced by shear stress.

  2011cites this paper
• Micromechanical regulation in cardiac myocytes and fibroblasts: implications for tissue remodeling

  2011cites this paper
• The biomechanical evaluation of aortic valve leaflet fusion in the LVAD-assisted heart

  2011cites this paper
• Cell-Cell Interactions and the Mechanics of Cells and Tissues Observed in Bioartificial Tissue Constructs

  2011cites this paper
• A DIGITAL VOLUME CORRELATION TECHNIQUE FOR 3-D DEFORMATION MEASUREMENTS OF SOFT GELS

  2011cites this paper
• STRUCTURAL DETERMINISTIC MODELING DESIGN AND FABRICATION OF ELECTROSPUN SCAFFOLDS FOR SOFT TISSUE ENGINEERING

  2011cites this paper
• Polymerization and matrix physical properties as important design considerations for soluble collagen formulations.

  2010cites this paper
• On the biomechanical function of scaffolds for engineering load-bearing soft tissues.

  2010cites this paper
• Out of Many, One: Modeling Schemes for Biopolymer and Biofibril Networks

  2010cites this paper
• Young's modulus of collagen at slow displacement rates

  2010cites this paper
• The Mechanical Environment of Cells in Collagen Gel Models

  2010cites this paper
• Spatiotemporal measurement of freezing-induced deformation of engineered tissues.

  2010cites this paper
• Fibril microstructure affects strain transmission within collagen extracellular matrices.

  2009cites this paper
• Strain-Induced Alignment in Collagen Gels

  2009cites this paper
• Scale-dependent fiber kinematics of elastomeric electrospun scaffolds for soft tissue engineering.

  2009cites this paper
• Strain-Induced Alignment in Collagen Gels The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters

  2009cites this paper
• Whole bone strain quantification by image registration: a validation study.

  2009cites this paper
• The modulus of fibroblast-populated collagen gels is not determined by final collagen and cell concentration: Experiments and an inclusion-based model.

  2009cites this paper
• Methods and applications of digital volume correlation

  2008cites this paper
• Biomimetic Collagen Tissues: Collagenous Tissue Engineering and Other Applications

  2008cites this paper
• Mechanical characterization of porous structures by the combined use of micro-CT and in-situ loading

  2008cites this paper
• Gold nanoparticles in biology: beyond toxicity to cellular imaging.

  2008cites this paper
• Chemical sensing and imaging with metallic nanorods.

  2008cites this paper
• Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus.

  2008cites this paper
• Nonlinear mechanics of soft fibrous networks

  2007cites this paper
• Stretch-induced nerve conduction deficits in guinea pig ex vivo nerve.

  2007cites this paper
• Using gold nanorods to probe cell-induced collagen deformation.

  2007cites this paper
• Volume-averaging theory for the study of the mechanics of collagen networks

  2007cites this paper
• Three-dimensional Full-field Measurements of Large Deformations in Soft Materials Using Confocal Microscopy and Digital Volume Correlation

  2007cites this paper
• Three‐Dimensional Reconstruction of Tissues

  2006cites this paper
• Biomechanics and Mechanotransduction in Cells and Tissues Extracellular matrix ( ECM ) microstructural composition regulates local cell-ECM biomechanics and fundamental fibroblast behavior : a multidimensional perspective

  2005influential citation