Produtos Naturais para o tratamento da doença de Alzheimer: Promessa e Desafio

A Doença de Alzheimer (DA) é uma patologia neurodegenerativa caracterizada por prejuízo das funções cognitivas e mudanças na personalidade, responsável por cerca de 50-60% dos casos de demência diagnosticados em pessoas com mais de 60 anos. O depósito cerebral de um peptídeo insolúvel, chamado peptídeo β-amilóide, e a presença de emaranhados neurofibrilares são considerados os marcadores neuropatológicos da doença. Somente cinco fármacos estão aprovados pelo FDA para o tratamento da DA, sendo que nenhum pode reverter o processo de neurodegeneração provocado pela doença. Atualmente o tratamento consiste apenas em aliviar temporariamente os sintomas, ou seja, não há cura para a DA. Portanto, em busca de substâncias potencialmente úteis para o tratamento da DA, os produtos naturais têm se destacado por apresentarem um papel importante na patologia da doença, não agindo somente na causa, mas também em seus mecanismos específicos.

• Publication year

  2005

• Venue

  Revista Fitos

• Publication date

  2005-11-30

• Fields of study

  Not labeled

• Identifiers
  DOI 10.32712/2446-4775.2005.22
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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