Protein-Bound 4-Hydroxy-2-Nonenal as a Marker of Oxidative Stress

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Clinical Biochemistry and Nutrition

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.3164/JCBN.36.1
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Structural Basis of Protein-bound Endogenous Aldehydes

  2003cited by this paper
• Immunological detection of 4-hydroxynonenal protein adducts in developing pontine and Purkinje neurons and in karyorrhexis in pontosubicular neuronal necrosis.

  2002cited by this paper
• Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients.

  2001cited by this paper
• Immunohistochemical detection of lipid peroxidation products, protein-bound acrolein and 4-hydroxynonenal protein adducts, in actinic elastosis of photodamaged skin

  2001cited by this paper
• Two Distinct Pathways of Formation of 4-Hydroxynonenal

  2001cited by this paper
• Oxidative and nitrosative stress in acute renal ischemia.

  2001cited by this paper
• Cyclopentenone Prostaglandins as Potential Inducers of Intracellular Oxidative Stress*

  2001cited by this paper
• Lipid peroxidation and peroxynitrite in retinal ischemia-reperfusion injury.

  2000cited by this paper
• Role of reactive aldehyde in cardiovascular diseases.

  2000cited by this paper
• 4‐Hydroxynonenal in the Pathomechanisms of Oxidative Stress

  2000cited by this paper
• Detection of lipofuscin‐like fluorophore in oxidized human low‐density lipoprotein

  2000cited by this paper
• Accumulation of 4-hydroxynonenal-modified proteins in hippocampal CA1 pyramidal neurons precedes delayed neuronal damage in the gerbil brain.

  2000cited by this paper
• Enhanced hepatic lipid peroxidation in patients with primary biliary cirrhosis

  2000cited by this paper
• Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation.

  2000cited by this paper
• Protein‐Bound Acrolein

  1999cited by this paper
• Rapid cross-linking of proteins by 4-ketoaldehydes and 4-hydroxy-2-alkenals does not arise from the lysine-derived monoalkylpyrroles.

  1999cited by this paper
• Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium.

  1999cited by this paper
• 4-Hydroxynonenal As a Biological Signal: Molecular Basis and Pathophysiological Implications

  1999cited by this paper
• A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein- and hydroxynonenal-modified proteins by epitope-bound casein matrix method.

  1999cited by this paper
• Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions.

  1999cited by this paper
• Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

  1999cited by this paper
• Heat-shock preconditioning reduces oxidative protein denaturation and ameliorates liver injury by carbon tetrachloride in rats

  1999cited by this paper
• Structure of a Fluorescent Compound Formed from 4-Hydroxy-2-nonenal and N(alpha)-Hippuryllysine: A Model for Fluorophores Derived from Protein Modifications by Lipid Peroxidation.

  1998cited by this paper
• 4-Hydroxynonenal and cell signalling.

  1998cited by this paper
• Soybean lipoxygenase-1 oxidizes 3Z-nonenal. A route to 4s-hydroperoxy-2e-nonenal and related products

  1998cited by this paper
• Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine.

  1998cited by this paper
• Structural characterization of a 4-hydroxy-2-alkenal-derived fluorophore that contributes to lipoperoxidation-dependent protein cross-linking in aging and degenerative disease.

  1998cited by this paper
• Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid.

  1998cited by this paper
• Covalent modifications of aminophospholipids by 4-hydroxynonenal.

  1998cited by this paper
• Increased mitochondrial damage by lipid peroxidation in trophoblast cells of preeclamptic placentas

  1997cited by this paper
• Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis

  1997cited by this paper
• Oxidative stress is found in amyloid deposits in systemic amyloidosis.

  1997cited by this paper
• Postischemic accumulation of lipid peroxidation products in the rat brain: immunohistochemical detection of 4-hydroxy-2-nonenal modified proteins.

  1997cited by this paper
• Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins.

  1996cited by this paper
• Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease.

  1996cited by this paper
• Immunochemical evidence supporting 2-pentylpyrrole formation on proteins exposed to 4-hydroxy-2-nonenal.

  1996cited by this paper
• Iron-induced carcinogenesis: the role of redox regulation.

  1996cited by this paper
• 4-Hydroxy-2-nonenal-trapping ELISA: direct evidence for the release of a cytotoxic aldehyde from oxidized low density lipoproteins.

  1995cited by this paper
• Characterization of epitopes recognized by 4-hydroxy-2-nonenal specific antibodies.

  1995cited by this paper
• The monoclonal antibody specific for the 4‐hydroxy‐2‐nonenal histidine adduct

  1995cited by this paper
• Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal.

  1995cited by this paper
• Formation of 8‐hydroxy‐2′‐deoxyguanosine and 4‐hydroxy‐2‐nonenal‐modified proteins in human renal‐cell carcinoma

  1994cited by this paper
• Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis.

  1994cited by this paper
• Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate.

  1994cited by this paper
• Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction.

  1993cited by this paper
• 2,3-epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation.

  1993cited by this paper
• Oxygenation of (3Z)-nonenal to (2E)-4-hydroxy-2-nonenal in the broad bean (Vicia faba L.).

  1993cited by this paper
• Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes.

  1993cited by this paper
• Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine.

  1993cited by this paper
• Pyrrole formation from 4-hydroxynonenal and primary amines.

  1993cited by this paper
• Studies on epitopes on low-density lipoprotein modified by 4-hydroxynonenal. Biochemical characterization and determination.

  1992cited by this paper
• Modification of histidine residues in proteins by reaction with 4-hydroxynonenal.

  1992cited by this paper
• Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.

  1991cited by this paper
• Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal.

  1991cited by this paper
• Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits.

  1990cited by this paper
• Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein.

  1990cited by this paper
• Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids.

  1990cited by this paper
• Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.

  1989cited by this paper
• Low density lipoprotein undergoes oxidative modification in vivo.

  1989cited by this paper
• Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

  1989cited by this paper
• 1,N2-ethenodeoxyguanosine as a potential marker for DNA adduct formation by trans-4-hydroxy-2-nonenal.

  1988cited by this paper
• Formation of cyclic adducts of deoxyguanosine with the aldehydes trans-4-hydroxy-2-hexenal and trans-4-hydroxy-2-nonenal in vitro.

  1986cited by this paper
• Possible involvement of the lipid-peroxidation product 4-hydroxynonenal in the formation of fluorescent chromolipids.

  1986cited by this paper
• Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids.

  1980cited by this paper
• Formation and properties of reactive aldehydes.

  1978cited by this paper
• The reaction of cysteine with α,β-unsaturated aldehydes

  1976cited by this paper
• Reaction of Glutathione with Conjugated Carbonyls

  1975cited by this paper
• Über die Reaktion von Protein-SH-Gruppen mit 4-Hydroxypentenal

  1971cited by this paper

• Protein carbonylation: molecular mechanisms, biological implications, and analytical approaches

  2020cites this paper
• Low Levels of IgG Recognizing the Alpha-1-Antitrypsin (A1AT) 50-63 Peptide and Its Association with Taiwanese Women with Primary Sjögren's Syndrome

  2017cites this paper
• Low Levels of IgG Recognizing the α-1-Antitrypsin Peptide and Its Association with Taiwanese Women with Primary Sjögren’s Syndrome

  2017cites this paper
• Oxidative damage and myofiber degeneration in the gastrocnemius of patients with peripheral arterial disease

  2013cites this paper
• Repeated short-term daily exercise ameliorates oxidative cerebral damage and the resultant motor dysfunction after transient ischemia in rats

  2013cites this paper
• A mass spectrometric analysis of 4-hydroxy-2-(E)-nonenal modification of cytochrome c.

  2011cites this paper
• Neutrophil-Dependent Oxidative Stress in Inflammatory Gastrointestinal Diseases

  2010cites this paper
• Determination of Oxidation Compounds and Oligomers by Chromatographic Techniques

  2010cites this paper
• Evaluation of the toxicity of stress-related aldehydes to photosynthesis in chloroplasts

  2009cites this paper
• Oxidative stress-induced posttranslational modification of proteins as a target of functional food.

  2009cites this paper
• Astaxanthin protects mesangial cells from hyperglycemia‐induced oxidative signaling

  2008cites this paper
• Molecular mechanisms of oxidative stress‐induced carcinogenesis: From epidemiology to oxygenomics

  2008cites this paper
• trans,trans-2,4-decadienal induces mitochondrial dysfunction and oxidative stress

  2008cites this paper
• Intake of n-3 Polyunsaturated Fatty Acids and In Vivo Lipid Peroxidation

  2008cites this paper
• Covalent modification of cytochrome c exposed to trans,trans-2,4-decadienal.

  2007cites this paper
• Neutrophil-Dependent Oxidative Stress in Ulcerative Colitis

  2007cites this paper
• Pathological investigation of oxidative stress in the post‐genomic era

  2007cites this paper
• Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation

  2007cites this paper
• Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease

  2007cites this paper
• Docosahexaenoic Acid-Induced Lipid Peroxidation and Urinary Excretion of Mercapturic Acid in Rats

  2006cites this paper
• Oxidative Stress-induced Cacinogenesis and Its Prevention Historical Aspects of Free Radical Chemistry and Biology: What’s New in Oxidative Stress-induced Carcinogenesis and Its Prevention?

  2006cites this paper
• What has been Learned from the Studies of Oxidative Stress-induced Carcinogenesis: Proposal of the Concept of Oxygenomics

  2006cites this paper
• Historical Aspects of Free Radical Chemistry and Biology: What's New in Oxidative Stress-induced Carcinogenesis and Its Prevention?

  2006cites this paper
• Increased F2-Isoprostane Levels in the Rat Brain and Plasma Caused by Oxidative Stress and Aging, and Inhibitory Effect of Vitamin E

  2006cites this paper