Trim39 inhibits the ability of APC/CCdh1 to ubiquitylate and promote the degradation of MOAP-1, leading to enhanced apoptosis.
The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1
Nai-Jia Huang,Liguo Zhang,Wanli Tang,Chen Chen,Chih-Sheng Yang,S. Kornbluth
Published 2012 in Journal of Cell Biology
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- Publication year
2012
- Venue
Journal of Cell Biology
- Publication date
2012-04-30
- Fields of study
Biology, Medicine
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Semantic Scholar
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