The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1

Nai-Jia Huang,Liguo Zhang,Wanli Tang,Chen Chen,Chih-Sheng Yang,S. Kornbluth

Published 2012 in Journal of Cell Biology

ABSTRACT

Trim39 inhibits the ability of APC/CCdh1 to ubiquitylate and promote the degradation of MOAP-1, leading to enhanced apoptosis.

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