Excitability Changes of the Mauthner Cell during Collateral Inhibition

Excitability changes during collateral inhibition of the goldfish Mauthner cell (M cell) were measured directly by stimulating the cell with current pulses applied through an intracellular electrode. Excitability was suppressed during the extrinsic hyperpolarizing potential (EHP) as well as during the collateral IPSP. The inhibitory effect of the EHP was shown to be comparable in intensity to the effect of the IPSP. Excitability changes in the M cell during collateral IPSP depended on changes in the membrane conductance as well as in the membrane potential. Some simple equations are advanced which describe the excitability change during the IPSP in terms of changes in membrane potential and conductance. It was also found that invasion of antidromic impulses into the M cell was suppressed during the EHP, but not during the collateral IPSP. Conductance increase during the IPSP did not interfere with the invasion of antidromic impulses.

• Publication year

  1965

• Venue

  The Journal of General Physiology

• Publication date

  1965-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1085/JGP.48.4.581PMID 14324977PMCID 2195433
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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