Decreased CD4 and wide-ranging expression of other immune receptors after HIV-envelope-mediated formation of syncytia in vitro

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Archives of Virology

• Publication date

  2010-05-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00705-010-0704-2PMID 20508956
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2009cited by this paper
• HIV Expression in Surgical Specimens

  2008cited by this paper
• Active Replication of HIV-1 at the Lymphoepithelial Surface of the Tonsil

  2007cited by this paper
• In vitro cell fusion between CD4(+) and HIV-1 Env(+) T cells generates a diversity of syncytia varying in total number, size and cellular content.

  2007cited by this paper
• Discriminating in vitro cell fusion from cell aggregation by flow cytometry combined with fluorescence resonance energy transfer.

  2006cited by this paper
• Role of Low CD4 Levels in the Influence of Human Immunodeficiency Virus Type 1 Envelope V1 and V2 Regions on Entry and Spread in Macrophages

  2005cited by this paper
• Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis.

  2005cited by this paper
• Molecular interactions at the T cell-antigen-presenting cell interface.

  2004cited by this paper
• Jurkat T cells and development of the T-cell receptor signalling paradigm

  2004cited by this paper
• CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo.

  2003cited by this paper
• Mitochondrial Apoptosis Induced by the HIV‐1 Envelope

  2003cited by this paper
• Human immunodeficiency virus envelope-dependent cell-cell fusion: a quantitative fluorescence cytometric assay.

  2002cited by this paper
• CD4 Independence of Simian Immunodeficiency Virus Envs Is Associated with Macrophage Tropism, Neutralization Sensitivity, and Attenuated Pathogenicity

  2002cited by this paper
• Syncytium formation amplifies apoptotic signals: a new view on apoptosis in HIV infection in vitro.

  2001cited by this paper
• Membrane-Fusing Capacity of the Human Immunodeficiency Virus Envelope Proteins Determines the Efficiency of CD4+ T-Cell Depletion in Macaques Infected by a Simian-Human Immunodeficiency Virus

  2001cited by this paper
• In vivo cytolysis and fusion of human immunodeficiency virus type 1-infected lymphocytes in lymphoid tissue.

  2000cited by this paper
• In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline.

  2000cited by this paper
• Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease.

  1999cited by this paper
• Actin-Dependent Receptor Colocalization Required for Human Immunodeficiency Virus Entry into Host Cells

  1998cited by this paper
• Association of syncytium‐inducing phenotype of HIV‐1 with CD4 cell count, viral load and sociodemographic characteristics

  1998cited by this paper
• HIV entry and its inhibition.

  1998cited by this paper
• Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure.

  1998cited by this paper
• Active replication of HIV-1 at the lymphoepithelial surface of the tonsil.

  1997cited by this paper
• Quantitative Contribution of CD4 and CD8 to T Cell Antigen Receptor Serial Triggering

  1997cited by this paper
• Circular forms of unintegrated human immunodeficiency virus type 1 DNA and high levels of viral protein expression: association with dementia and multinucleated giant cells in the brains of patients with AIDS

  1997cited by this paper
• Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals

  1997cited by this paper
• Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function.

  1996cited by this paper
• Broader tropism and higher cytopathicity for CD4+ T cells of a syncytium-inducing compared to a non-syncytium-inducing HIV-1 isolate as a mechanism for accelerated CD4+ T cell decline in vivo.

  1996cited by this paper
• Molecular determinants of acute single-cell lysis by human immunodeficiency virus type 1

  1996influential reference
• Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus type 1

  1995cited by this paper
• Autologous rat myelin basic protein is a partial agonist that is converted into a full antagonist upon blockade of CD4. Evidence for the integration of efficacious and nonefficacious signals during T cell antigen recognition.

  1995cited by this paper
• Sensitive method for measuring apoptosis and cell surface phenotype in human thymocytes by flow cytometry.

  1994cited by this paper
• Adhesion Mediated by Intercellular Adhesion Molecule 1 Attenuates the Potency of Antibodies That Block HIV-1 gp160-Dependent Syncytium Formation

  1994cited by this paper
• Changing Virus‐Host Interactions in the Course of HIV‐1 Infection

  1994cited by this paper
• Cell surface down‐modulation of CD4 after infection by HIV‐1

  1994cited by this paper
• Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals

  1993cited by this paper
• Prognostic Value of HIV-1 Syncytium-Inducing Phenotype for Rate of CD4+ Cell Depletion and Progression to AIDS

  1993cited by this paper
• Kinetics of soluble CD4 binding to cells expressing human immunodeficiency virus type 1 envelope glycoprotein

  1992cited by this paper
• CD4 epitope masking by gp120/anti-gp120 antibody complexes. A potential mechanism for CD4+ cell function down-regulation in AIDS patients.

  1992cited by this paper
• Target cell-specific determinants of membrane fusion within the human immunodeficiency virus type 1 gp120 third variable region and gp41 amino terminus

  1992cited by this paper
• Internalization of HIV glycoprotein gp120 is associated with down-modulation of membrane CD4 and p56lck together with impairment of T cell activation.

  1992cited by this paper
• Human immunodeficiency virus (HIV) infection in CD4+ T lymphocytes genetically deficient in LFA-1: LFA-1 is required for HIV-mediated cell fusion but not for viral transmission

  1991cited by this paper
• Human immunodeficiency virus-infected multinucleated histiocytes in oropharyngeal lymphoid tissues from two asymptomatic patients.

  1991cited by this paper
• Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.

  1991cited by this paper
• Current protocols in immunology

  1991cited by this paper
• Dissociation of gp120 from HIV-1 virions induced by soluble CD4.

  1990cited by this paper
• CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor

  1990cited by this paper
• Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation.

  1989cited by this paper
• Envelope glycoprotein of HIV induces interference and cytolysis resistance in CD4+ cells: mechanism for persistence in AIDS.

  1988cited by this paper
• Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

  1986cited by this paper
• AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen.

  1986cited by this paper
• Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus.

  1986cited by this paper

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  2017cites this paper
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  2015cites this paper
• Flow cytometry analysis of cell population dynamics and cell cycle during HIV-1 envelope-mediated formation of syncytia in vitro

  2014influential citation
• Changes in the HIV-1 env gene: Implications at the RNA and protein structure levels

  2012cites this paper
• Constrained peptide models from phage display libraries highlighting the cognate epitope-specific potential of the anti-HIV-1 mAb 2F5.

  2011cites this paper
• Quantitative and phenotypic analyses of lymphocyte-monocyte heterokaryons induced by the HIV envelope proteins: Significant loss of lymphoid markers.

  2011cites this paper
• CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis

  2011cites this paper
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  year unknowncites this paper