Identification of functional α2- and β-adrenergic receptors in mammalian spermatozoa

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Human Reproduction

• Publication date

  2006-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/HUMREP/DEL016
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Cathine and norephedrine, both phenylpropanolamines, accelerate capacitation and then inhibit spontaneous acrosome loss.

  2005influential reference
• A mouse sperm decapacitation factor receptor is phosphatidylethanolamine-binding protein 1.

  2005influential reference
• Mechanisms of action of angiotensin II on mammalian sperm function.

  2005cited by this paper
• Human sperm responses to calcitonin, angiotensin II and fertilization-promoting peptide in prepared semen samples from normal donors and infertility patients.

  2004cited by this paper
• The sperm, a neuron with a tail:‘neuronal’receptors in mammalian sperm

  2004cited by this paper
• Immunolocalization of multiple Gα subunits in mammalian spermatozoa and additional evidence for Gαs

  2003influential reference
• Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa

  2003influential reference
• In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates

  2003cited by this paper
• Capacitation and induction of the acrosome reaction in bull spermatozoa with norepinephrine.

  2002cited by this paper
• Capacitation state‐dependent changes in adenosine receptors and their regulation of adenylyl cyclase/cAMP

  2002cited by this paper
• Bicarbonate-regulated soluble adenylyl cyclase.

  2001cited by this paper
• Identification of norepinephrine in bovine oviductal fluid by high performance liquid chromatography.

  2001influential reference
• Fertilization promoting peptide and adenosine, acting as first messengers, regulate cAMP production and consequent protein tyrosine phosphorylation in a capacitation‐dependent manner

  2000cited by this paper
• Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals.

  1999cited by this paper
• Modulation of adenylyl cyclase by FPP and adenosine involves stimulatory and inhibitory adenosine receptors and g proteins

  1999cited by this paper
• TCP‐11, the product of a mouse t‐complex gene, plays a role in stimulation of capacitation and inhibition of the spontaneous acrosome reaction

  1997cited by this paper
• Isozyme-dependent Sensitivity of Adenylyl Cyclases to P-site-mediated Inhibition by Adenine Nucleosides and Nucleoside 3′-Polyphosphates*

  1997cited by this paper
• The Sigma-RBI handbook of receptor classification and signal transduction

  1995cited by this paper
• Stimulating effect of pyroglutamylglutamylprolineamide, a prostatic, TRH‐related tripeptide, on mouse sperm capacitation and fertilizing ability in vitro

  1994cited by this paper
• In vitro capacitation and fertilization.

  1993influential reference
• Cathinone, a natural amphetamine.

  1992cited by this paper
• Amphetamine-like effects in humans of the khat alkaloid cathinone.

  1990cited by this paper
• No evidence of the existence of beta adrenoceptors in human sperm using radioligand binding technique.

  1989cited by this paper
• Epinephrine decreases the potassium requirements of hamster sperm capacitation: furosemide blocks the effect of epinephrine.

  1985cited by this paper
• Mouse sperm capacitation in vitro involves loss of a surface-associated inhibitory component.

  1984cited by this paper
• Serotonin or its agonist 5-methoxytryptamine can stimulate hamster sperm acrosome reactions in a more direct manner than catecholamines.

  1983influential reference
• 9-AAP, a fluorescent beta-adrenergic antagonist, enters the hamster sperm acrosome in a manner inconsistent with binding to beta-adrenergic receptors.

  1980cited by this paper
• Further evidence suggesting the hormonal stimulation of hamster sperm acrosome reactions by catecholamines in vitro.

  1980cited by this paper
• Adrenergic stimulation of fertilizing ability in hamster spermatozoa.

  1979cited by this paper
• Catecholamine requirement for hamster sperm motility in vitro.

  1979cited by this paper
• Stimulation of in vitro activation and the acrosome reaction of hamster spermatozoa by catecholamines.

  1978influential reference
• Capacitation of hamster spermatozoa with adrenal gland extracts.

  1976cited by this paper
• The ‘Capacitation’ of the Mammalian Sperm

  1952cited by this paper

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  2022cites this paper
• N-Formyl-L-aspartate mediates chemotaxis in sperm via the beta-2-adrenergic receptor

  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
• β-adrenergic receptors in the up-regulation of COX2 expression and prostaglandin production in testicular macrophages: Possible relevance to male idiopathic infertility.

  2019cites this paper
• Transgenerational Epigenetics of Traumatic Stress.

  2018cites this paper
• Neuronal signaling repertoire in the mammalian sperm functionality

  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
• Effects of repeated administration of methylphenidate on reproductive parameters in male rats.

  2014cites this paper
• Diagnosis and prognosis of male infertility in mammal: the focusing of tyrosine phosphorylation and phosphotyrosine proteins.

  2014cites this paper
• Boar Spermatozoa Within the Oviductal Environment (II): Sperm Capacitation

  2013cites this paper
• Functional activity of adenylyl and guanylyl cyclases in human spermatozoa with different motility

  2013cites this paper
• Methylphenidate has dose-dependent negative effects on rat spermatogenesis: decreased round spermatids and testicular weight and increased p53 expression and apoptosis

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  2010cites this paper
• The “switching on” of mammalian spermatozoa: Molecular events involved in promotion and regulation of capacitation

  2010cites this paper
• The role of small molecules in sperm capacitation.

  2008cites this paper
• Zilpaterol Hydrochloride on Performance and Sperm Quality of Lambs Fed Wet Brewers Grains

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• Comparative immunolocalization of heat shock proteins (Hsp)-60, -70, -90 in boar, stallion, dog and cat spermatozoa.

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• Expression of adrenergic receptors in mouse preimplantation embryos and ovulated oocytes.

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  2006cites this paper
• The potential impact of novel investigational compounds on human fertility

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• In vitro Effects of Propranolol on Human Sperm Motility

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