ATP suppression of interleukin‐12 and tumour necrosis factor‐α release from macrophages

No abstract is available for this paper.

• Publication year

  2000

• Venue

  British Journal of Pharmacology

• Publication date

  2000-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/sj.bjp.0703134PMCID PMC1571917
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• IL‐12 as a therapeutic target for pharmacological modulation in immune‐mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responses

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• IL‐12 directs severe renal injury, crescent formation and Th1 responses in murine glomerulonephritis

  1999cited by this paper
• Increased release of ATP from endothelial cells during acute inflammation

  1998cited by this paper
• The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses.

  1998cited by this paper
• ATP released by LPS increases nitric oxide production in raw 264.7 macrophage cell line via P2Z/P2X7 receptors.

  1998cited by this paper
• The crucial role of IL‐10 in the suppression of the immunological response in mice exposed to staphylococcal enterotoxin B

  1998cited by this paper
• Activation of purinergic P2Y2 receptors inhibits inducible NO synthase in cultured rat mesangial cells.

  1998cited by this paper
• Receptors for purines and pyrimidines.

  1998influential reference
• Studies of expression and possible functional role of purinergic receptors in cell‐mediated immunity: Experimental approaches, controls, and caveats

  1998cited by this paper
• Regulation of cytokine and chemokine production by transmitters and co-transmitters of the autonomic nervous system.

  1998cited by this paper
• cAMP and purinergic P2y receptors upregulate and enhance inducible NO synthase mRNA and protein in vivo.

  1997cited by this paper
• cAMP and purinergic P2yreceptors upregulate and enhance inducible NO synthase mRNA and protein in vivo.

  1997cited by this paper
• Extracellular ATP Activates Transcription Factor NF-κB through the P2Z Purinoreceptor by Selectively Targeting NF-κB p65 (RelA)

  1997cited by this paper
• Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12.

  1997cited by this paper
• Interaction of Ethanol with Inducible Nitric Oxide Synthase Messenger RNA and Protein : Direct Effects on Autacoids and Endotoxin In Vivo 1 , 2

  1997cited by this paper
• Purinergic Modulation of Interleukin-1β Release from Microglial Cells Stimulated with Bacterial Endotoxin

  1997cited by this paper
• Regulation of Inducible Nitric Oxide Synthase Expression by Macrophage Purinoreceptors and Calcium (*)

  1996cited by this paper
• Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.

  1996cited by this paper
• Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit.

  1996cited by this paper
• Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice

  1995cited by this paper
• Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

  1995cited by this paper
• Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12

  1995cited by this paper
• Antibodies to interleukin 12 abrogate established experimental colitis in mice

  1995cited by this paper
• Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice.

  1995cited by this paper
• The P2Z purinoceptor: an intriguing role in immunity, inflammation and cell death

  1995cited by this paper
• Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity.

  1995cited by this paper
• Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction

  1994cited by this paper
• Extracellular ATP potentiates nitric oxide synthase expression induced by lipopolysaccharide in RAW 264.7 murine macrophages.

  1994cited by this paper
• Interleukin 10 (IL-10) Inhibits Human Lymphocyte Interferon 3,-Production by Suppressing Natural Killer Cell Stimulatory Factor/IL-12 Synthesis in Accessory Cells By Annalisa D'Andrea, Miguel Aste-Amezaga,

  1993cited by this paper
• Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides.

  1993cited by this paper
• Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma- production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

  1993cited by this paper
• Interleukin 1 is processed and released during apoptosis.

  1991cited by this paper
• Neural Release of ATP and Adenosine a

  1990cited by this paper
• Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.

  1989cited by this paper

• The Effect of Lipopolysaccharide on Anxiety Levels in Rats Exposed to Chronic Unpredictable Mild Stress of Varying Duration.

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• NTPDase8 Protects Against Liver Ischemia–Reperfusion Injury in Mice

  2025cites this paper
• Beyond the surface: P2Y receptor downstream pathways, TLR crosstalk and therapeutic implications for infection and autoimmunity.

  2025cites this paper
• Protective effect of adenosine triphosphate against cisplatin-induced necrotic and degenerative oral mucositis in rats

  2025cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2020cites this paper
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  2020cites this paper
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  2018cites this paper
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  2018cites this paper
• Targeting Adenosine Receptor Signaling in Cancer Immunotherapy

  2018cites this paper
• Extracellular ATP and adenosine: The Yin and Yang in immune responses?

  2017cites this paper
• ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE

  2016cites this paper
• Do not let death do us part: ‘find-me’ signals in communication between dying cells and the phagocytes

  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
• The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis

  2015cites this paper
• Extracellular adenosine triphosphate affects the response of human macrophages infected with Mycobacterium tuberculosis.

  2014cites this paper
• The effect of extracellular nucleotides on cytokine production and phagocytosis of macrophages

  2014cites this paper
• Plasma‐mediated immune suppression: a neonatal perspective

  2013cites this paper
• Interleucina-12 em crianças com sepse e choque séptico

  2012cites this paper
• P2 receptors and immunity

  2012cites this paper
• A Protective Role for Inflammasome Activation Following Injury

  2012cites this paper
• Neonatal Plasma Polarizes TLR4-Mediated Cytokine Responses towards Low IL-12p70 and High IL-10 Production via Distinct Factors

  2012cites this paper
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  2012cites this paper
• Mechanisms of microenvironmental conditioning in non-Hodgkin’s lymphoma

  2012cites this paper
• Neonatal innate immunity - A translational perspective

  2012cites this paper
• P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation.

  2011cites this paper
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  2011cites this paper
• Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways.

  2011cites this paper
• Salivary Gland Protein Repertoire from Aedes aegypti Mosquitoes

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
• Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being.

  2008influential citation
• Role of nonsynaptic communication in regulating the immune response.

  2008cites this paper
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  2008cites this paper
• P2 purinergic receptor modulation of cytokine production

  2007cites this paper
• Shaping of monocyte and macrophage function by adenosine receptors.

  2007cites this paper
• Gene expression studies in multiple sclerosis.

  2007cites this paper
• Purinergic Signaling in Inflammation and Immunomodulation

  2006cites this paper
• Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation.

  2006cites this paper
• Protective Effect of Purinergic Agonist AtpΓS against Acute Lung Injury

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• Cytokine Dysregulation, Inflammation and Well-Being

  2005cites this paper
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  2005cites this paper
• Addicted to Death: Invasive Cancer and the Immune Response to Unscheduled Cell Death

  2005cites this paper
• Increased susceptibility of purinergic receptor-deficient mice to lung infection with Pseudomonas aeruginosa.

  2005influential citation
• Cytokine Production Alterations in Lipopolysaccharide-Induced Monocyte Pore Assay Predictive of Receptor Polymorphisms by a Novel Nucleotide 7 Detection of Human P 2 X

  2005cites this paper
• Cellular distribution and functions of P2 receptor subtypes in different systems.

  2004cites this paper
• Adenosine and ATP affect LPS-induced cytokine production by macrophages

  2003cites this paper
• The sympathetic-immune interface: role in immune regulation and pathology

  2003cites this paper
• Adenosine suppresses activation of nuclear factor-κB selectively induced by tumor necrosis factor in different cell types

  2003cites this paper
• Alerting and tuning the immune response by extracellular nucleotides

  2003cites this paper
• Nucleotidase Cascades Are Catalyzed by Secreted Proteins of the Parasitic Nematode Trichinella spiralis

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• Redox- and oxidant-mediated regulation of interleukin-10: an anti-inflammatory, antioxidant cytokine?

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• Receptor-Mediated Interaction Between the Sympathetic Nervous System and Immune System in Inflammation

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