Bilirubin‐UDP‐glucuronosyltransferase: Genetic defect of the hyperbilirubinemic gunn rat, a model of crigler‐najjar syndrome type I

No abstract is available for this paper.

• Publication year

  1994

• Venue

  STEM CELLS

• Publication date

  1994-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/stem.5530120714
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• A mutation in bilirubin uridine 5'-diphosphate-glucuronosyltransferase isoform 1 causing Crigler-Najjar syndrome type II.

  1993cited by this paper
• Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II.

  1993cited by this paper
• Sequence of exons and the flanking regions of human bilirubin‐UDP‐glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler‐Najjar syndrome, type I

  1992cited by this paper
• Identification of a genetic alteration in the code for bilirubin UDP-glucuronosyltransferase in the UGT1 gene complex of a Crigler-Najjar type I patient.

  1992cited by this paper
• The novel bilirubin/phenol UDP-glucuronosyltransferase UGT1 gene locus: implications for multiple nonhemolytic familial hyperbilirubinemia phenotypes.

  1992cited by this paper
• A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

  1992cited by this paper
• Retroviral-mediated gene transfer into hepatocytes in vivo.

  1991cited by this paper
• Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells.

  1991cited by this paper
• Molecular basis for the lack of bilirubin-specific and 3-methylcholanthrene-inducible UDP-glucuronosyltransferase activities in Gunn rats. The two isoforms are encoded by distinct mRNA species that share an identical single base deletion.

  1991cited by this paper
• Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.

  1991cited by this paper
• The UDP Glucuronosyltransferase Gene Super family: Suggested Nomenclature Based on Evolutionary Divergence

  1991cited by this paper
• Molecular basis of multiple UDP-glucuronosyltransferase isoenzyme deficiencies in the hyperbilirubinemic rat (Gunn rat).

  1991cited by this paper
• Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat.

  1991cited by this paper
• Isolation and sequencing of rat liver bilirubin UDP-glucuronosyltransferase cDNA: possible alternate splicing of a common primary transcript.

  1990cited by this paper
• The 3-methylcholanthrene-inducible UDP-glucuronosyltransferase deficiency in the hyperbilirubinemic rat (Gunn rat) is caused by a -1 frameshift mutation.

  1989cited by this paper
• UDP-glucur-onosyltransferases

  1989cited by this paper
• Studies on the genetic linkage of bilirubin and androsterone UDP-glucuronyltransferases by cross-breeding of two mutant rat strains.

  1988cited by this paper
• Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme.

  1987cited by this paper
• Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase.

  1986cited by this paper
• Congenital jaundice in rats, due to a defect in glucuronide formation.

  1958cited by this paper
• HEREDITARY ACHOLURIC JAUNDICEin a New Mutant Strain of Rats

  1938cited by this paper
• Cloning of Two Human Liver Bilirubin UDP-glucuronosyl-transferase cDNAs with Expression in COS-1 Cells *

  year unknowncited by this paper

• [Proteins in response to environmental stress].

  2002cites this paper
• Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins.

  1998cites this paper
• Biochemical and molecular aspects of genetic disorders of bilirubin metabolism.

  1998cites this paper