In situ detection of the intermediates in the biosynthesis of surfactin, a lipoheptapeptide from Bacillus subtilis OKB 105, by whole-cell cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in combination with mutant analysis.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Rapid Communications in Mass Spectrometry

• Publication date

  2009-05-30

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/rcm.4031PMID 19350532
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Whole-cell matrix-assisted laser desorption/ionization mass spectrometry for rapid identification of bacteriocin/lantibiotic-producing bacteria.

  2008cited by this paper
• Surfactants in microbiology and biotechnology: Part 2. Application aspects.

  2007cited by this paper
• Biosurfactants: potential applications in medicine.

  2006cited by this paper
• Dissecting non-ribosomal and polyketide biosynthetic machineries using electrospray ionization Fourier-Transform mass spectrometry.

  2006cited by this paper
• Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry.

  2006cited by this paper
• Whole cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and in situ structure analysis of streptocidins, a family of tyrocidine-like cyclic peptides.

  2005cited by this paper
• Bacillus subtilis antibiotics: structures, syntheses and specific functions

  2005cited by this paper
• Parallel interrogation of covalent intermediates in the biosynthesis of gramicidin S using high‐resolution mass spectrometry

  2005cited by this paper
• Recent applications of biosurfactants as biological and immunological molecules.

  2004cited by this paper
• Initiation of surfactin biosynthesis and the role of the SrfD-thioesterase protein.

  2004cited by this paper
• Structural and Functional Characterization of Gene Clusters Directing Nonribosomal Synthesis of Bioactive Cyclic Lipopeptides in Bacillus amyloliquefaciens Strain FZB42

  2004cited by this paper
• Genetic analysis of the biosynthesis of non-ribosomal peptide- and polyketide-like antibiotics, iron uptake and biofilm formation by Bacillus subtilis A1/3

  2004cited by this paper
• Kinetic and regiospecific interrogation of covalent intermediates in the nonribosomal peptide synthesis of yersiniabactin.

  2004cited by this paper
• Site-specific observation of acyl intermediate processing in thiotemplate biosynthesis by fourier transform mass spectrometry: the polyketide module of yersiniabactin synthetase.

  2003cited by this paper
• "Whole cell"--matrix-assisted laser desorption ionization-time of flight-mass spectrometry, an emerging technique for efficient screening of biocombinatorial libraries of natural compounds-present state of research.

  2003cited by this paper
• Diversity among microbial cyclic lipopeptides: iturins and surfactins. Activity-structure relationships to design new bioactive agents.

  2003cited by this paper
• Applications of MALDI‐TOF MS analysis in cyanotoxin research

  2002cited by this paper
• Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry of Lipopeptide Biosurfactants in Whole Cells and Culture Filtrates of Bacillus subtilis C-1 Isolated from Petroleum Sludge

  2002cited by this paper
• MALDI-TOF mass spectrometry of bacteria.

  2001cited by this paper
• Characterisation of bacteria by matrix-assisted laser desorption/ionisation and electrospray mass spectrometry.

  2000cited by this paper
• Characterisation of bacteria by matrix-assisted laser desorption/ionisation and electrospray mass spectrometry.

  2000cited by this paper
• Rapid typing of Bacillus subtilis strains by their secondary metabolites using matrix‐assisted laser desorption/ionization mass spectrometry of intact cells

  1999cited by this paper
• Assembly line enzymology by multimodular nonribosomal peptide synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization.

  1999cited by this paper
• Recent trends in the biochemistry of surfactin

  1999cited by this paper
• Separation and Characterization of Surfactin Isoforms Produced by Bacillus subtilis OKB 105

  1998cited by this paper
• Separation and Characterization of Surfactin Isoforms Produced byBacillus subtilisOKB 105

  1998cited by this paper
• Mechanism of inactivation of enveloped viruses by the biosurfactant surfactin from Bacillus subtilis.

  1997cited by this paper
• Rapid typing and elucidation of new secondary metabolites of intact cyanobacteria using MALDI-TOF mass spectrometry

  1997cited by this paper
• Microbial production of surfactants and their commercial potential

  1997cited by this paper
• Antimycoplasma properties and application in cell culture of surfactin, a lipopeptide antibiotic from Bacillus subtilis

  1997cited by this paper
• The Multiple Carrier Model of Nonribosomal Peptide Biosynthesis at Modular Multienzymatic Templates*

  1996cited by this paper
• Thyroid Hormone Modulates the Interaction between Iron Regulatory Proteins and the Ferritin mRNA Iron-responsive Element (*)

  1996cited by this paper
• Analysis of surfactin synthetase subunits in srfA mutants of Bacillus subtilis OKB105

  1994cited by this paper
• Structural and functional organization of the surfactin synthetase multienzyme system.

  1993cited by this paper
• Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis

  1993cited by this paper
• Characterization of the srfA locus of Bacillus subtilis: only the valine‐activating domain of srfA is involved in the establishment of genetic competence

  1993cited by this paper
• Cell-free biosynthesis of surfactin, a cyclic lipopeptide produced by Bacillus subtilis.

  1991cited by this paper
• srfA is an operon required for surfactin production, competence development, and efficient sporulation in Bacillus subtilis

  1991cited by this paper
• Identification of a genetic locus required for biosynthesis of the lipopeptide antibiotic surfactin in Bacillus subtilis

  1988cited by this paper
• Gramicidin S synthetase. Stability of reactive thioester intermediates and formation of 3-amino-2-piperidone.

  1983cited by this paper
• The protein thiotemplate mechanism of synthesis for the peptide antibiotics produced by Bacillus brevis.

  1973cited by this paper
• The protein thiotemplate mechanism of synthesis for the peptide antibiotics produced by Bacillus brevis.

  1973cited by this paper
• The nature of the enzyme bound intermediates in gramicidin s biosynthesis

  1970cited by this paper
• Peptidyl transfers in gramicidin S bisoynthesis from enzyme-bound thioester intermediates.

  1969cited by this paper
• Bacillomycin

  1948cited by this paper
• Bacillomycin; an antibiotic from Bacillus subtilis active against pathogenic fungi.

  1948cited by this paper

• Biotechnologically Derived Bioactive Molecules for Skin and Hair‐Care Application

  2021cites this paper
• Development and Genetic Engineering of Hyper-Producing Microbial Strains for Improved Synthesis of Biosurfactants

  2021cites this paper
• Optimized expression and enhanced production of alkaline protease by genetically modified Bacillus licheniformis 2709

  2020cites this paper
• Efficient production of extracellular pullulanase in Bacillus subtilis ATCC6051 using the host strain construction and promoter optimization expression system

  2018cites this paper
• Antifungal Lipopeptides Produced by Bacillus sp. FJAT-14262 Isolated from Rhizosphere Soil of the Medicinal Plant Anoectochilus roxburghii

  2017cites this paper
• Multigene disruption in undomesticated Bacillus subtilis ATCC 6051a using the CRISPR/Cas9 system

  2016cites this paper
• Isolation and Characterization of Marine Brevibacillus sp. S-1 Collected from South China Sea and a Novel Antitumor Peptide Produced by the Strain

  2014cites this paper
• Bringing microbial interactions to light using imaging mass spectrometry.

  2014cites this paper
• Metabolic potential of endophytic bacteria

  2014cites this paper
• Direct surfactin-gramicidin S antagonism supports detoxification in mixed producer cultures of Bacillus subtilis and Aneurinibacillus migulanus.

  2012influential citation
• Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics.

  2010cites this paper
• ΠΡΟΓΡΑΜΜΑ ΔΙΑ ΒΙΟΥ ΜΑΘΗΣΗΣ ΑΕΙ ΓΙΑ ΤΗΝ ΕΠΙΚΑΙΡΟΠΟΙΗΣΗ ΓΝΩΣΕΩΝ ΑΠΟΦΟΙΤΩΝ ΑΕΙ (ΠΕΓΑ)

  2010cites this paper
• Characterisation, Manipulation and Directed Evolution of Non-Ribosomal Peptide Synthetase Enzymes

  2010cites this paper
• Diversity of Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Lipopeptide Biosurfactants

  2010cites this paper