Development of a rapid and validated method for investigating the metabolism of scoparone in rat using ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Rapid Communications in Mass Spectrometry

• Publication date

  2007-12-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/RCM.3296PMID 17979104
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Multiresidue determination of thermolabile insecticides in cereal products by gas chromatography-mass spectrometry: evaluation with on-column injection and conventional hot splitless injection.

  2007cited by this paper
• Inhibition of cytokine-mediated nitric oxide synthase expression in rat insulinoma cells by scoparone.

  2007cited by this paper
• Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IkappaB/NF-kappaB signal cascade in the human mast cell line HMC-1.

  2007cited by this paper
• Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IκB/NF-κB signal cascade in the human mast cell line HMC-1

  2007cited by this paper
• Comparative immunomodulatory effect of scopoletin on tumoral and normal lymphocytes.

  2006cited by this paper
• Simultaneous analysis of trans- and cis-isomers of 2-glucosyloxycinnamic acids and coumarin derivatives in Dendrobium thyrsiflorum by high-performance liquid chromatography (HPLC)-photodiode array detection (DAD)-electrospray ionization (ESI)-tandem mass spectrometry (MS).

  2006cited by this paper
• Peak capacity in gradient ultra performance liquid chromatography (UPLC).

  2005cited by this paper
• UPLC™: An Introduction and Review

  2005cited by this paper
• Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress

  2005cited by this paper
• Evaluation of antiviral activity of compounds isolated from Ranunculus sieboldii and Ranunculus sceleratus.

  2005cited by this paper
• Ultra-performance liquid chromatography coupled to quadrupole-orthogonal time-of-flight mass spectrometry.

  2004cited by this paper
• Simultaneous quantitative analysis of three drugs by high-performance liquid chromatography/electrospray ionization mass spectrometry and its application to cassette in vitro metabolic stability studies.

  2003cited by this paper
• A theoretical study of the optimization of gradients at elevated temperature

  2001cited by this paper
• Rapid identification of saponins in plant extracts by electrospray ionization multi-stage tandem mass spectrometry and liquid chromatography/tandem mass spectrometry.

  2000cited by this paper
• Determination of Scoparone in Citrus Roots by Micellar Electrokinetic Capillary Chromatography

  2000cited by this paper
• Bioanalytical applications of 'fast chromatography' to high-throughput liquid chromatography/tandem mass spectrometric quantitation.

  2000cited by this paper
• Liquid chromatography-electrospray mass spectrometric identification of ginsenosides in Panax ginseng roots.

  1999cited by this paper
• The need for adequate chromatographic separation in the quantitative determination of drugs in biological samples by high performance liquid chromatography with tandem mass spectrometry

  1999cited by this paper
• Application of a generic fast gradient liquid chromatography tandem mass spectrometry method for the analysis of cytochrome P450 probe substrates.

  1998cited by this paper
• Derivatization procedures for gas chromatographic-mass spectrometric determination of xenobiotics in biological samples, with special attention to drugs of abuse and doping agents.

  1998cited by this paper
• Protection by scoparone against the alterations of plasma lipoproteins, vascular morphology and vascular reactivity in hyperlipidaemic diabetic rabbit

  1993cited by this paper
• Vasodilator effect of scoparone (6,7-dimethoxycoumarin) from a Chinese herb.

  1992cited by this paper
• Possible mechanism of immunosuppressive effect of scoparone (6,7-dimethoxycoumarin).

  1992cited by this paper
• Vasorelaxants from Chinese herbs, emodin and scoparone, possess immunosuppressive properties.

  1991cited by this paper
• Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985).

  1988cited by this paper

• Differentiating Tangerine Peels from Other Citrus reticulata through GC-MS, UPLC-Q-Exactive Orbitrap-MS, and HPLC-PDA

  2024cites this paper
• Comparative pharmacokinetics of Scoparone and its metabolite Scopoletin in normal and ANIT-induced intrahepatic cholestatic rats.

  2023cites this paper
• The Arbuscular Mycorrhizal Fungus Rhizophagus irregularis MUCL 41833 Modulates Metabolites Production of Anchusa officinalis L. Under Semi-Hydroponic Cultivation

  2021cites this paper
• UPLC-Q-Exactive Orbitrap MS Analysis for Identification of Lipophilic Components in Citri Sarcodactylis Fructus from Different Origins in China Using Supercritical CO2 Fluid Extraction Method

  2020cites this paper
• Identification of lipophilic components in Citri Reticulatae Pericarpium cultivars by supercritical CO2 fluid extraction with ultra-high-performance liquid chromatography-Q Exactive Orbitrap tandem mass spectrometry.

  2020cites this paper
• Systematic analysis of the metabolites of Angelicae Pubescentis Radix by UPLC-Q-TOF-MS combined with metabonomics approaches after oral administration to rats.

  2020cites this paper
• Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter

  2020cites this paper
• Metabolism of Scoparone in Experimental Animals and Humans

  2019cites this paper
• High-throughput chinmedomics strategy for discovering the quality-markers and potential targets for Yinchenhao decoction.

  2019cites this paper
• Discovery and verification of the potential targets from bioactive molecules by network pharmacology-based target prediction combined with high-throughput metabolomics

  2017cites this paper
• Comparison of In Vitro Hepatic Scoparone 7-O-Demethylation between Humans and Experimental Animals

  2017cites this paper
• Using Light Microscopy and Liquid Chromatography Tandem Mass Spectrometry for Qualitative and Quantitative Control of a Combined Three-Herb Formulation in Different Preparations

  2016cites this paper
• Mass spectrometry based molecular profile dissects the complexity of traditional Chinese medicine

  2015cites this paper
• Antioxidant and intestinal anti-inflammatory effects of plant-derived coumarin derivatives.

  2014cites this paper
• The use of partially porous particle columns for the routine, generic analysis of biological samples for pharmacokinetic studies in drug discovery by reversed-phase ultra-high performance liquid chromatography-tandem mass spectrometry.

  2009cites this paper