In patients with type 1 and type 2 diabetes mellitus (DM), respiratory function abnormalities have been reported with regard to lung volumes, pulmonary diffusing capacity, control of ventilation, bronchomotor tone, and neuroadrenergic bronchial innervation. Indeed, the decrease in lung volumes and the impairment of diffusing capacity might have important clinical implications. Furthermore, there is an increasing evidence of a link between DM and pulmonary hypertension (PH) related to an involvement of the pulmonary vascular structures. These findings support the view of the lung as target organ in DM. In this paper, we briefly describe the main derangements of the respiratory system in DM and the inherent mechanisms.
Diabetic lung, an underrated complication from restrictive functional pattern to pulmonary hypertension
L. Fuso,D. Pitocco,R. Antonelli-Incalzi
Published 2019 in Diabetes/Metabolism Research Reviews
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
Diabetes/Metabolism Research Reviews
- Publication date
2019-04-16
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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