Functional Virus-Like Particles Production Using Silkworm and Their Application in Life Science

Virus-like particles (VLPs), which mimic the structure of authentic virus, are of significant importance owing to their wide ranging applications. VLPs have the potential to serve as candidate vaccine in addition to subunit vaccines and also serve as a nano-bioparticle scaffold for displaying complex foreign proteins. Here, we review different methods available to produce VLPs with various host expression systems including from microorganisms to mammalian cells and the current potential of silkworms as producers of these VLPs. Recently, silkworms have been used for efficient production of VLPs too in addition to mass production of recombinant proteins, which have contributed to molecular structural analysis, molecule–molecule interactions in biology and biotechnology.

• Publication year

  2012

• Venue

  Journal of biotechnology & biomaterials

• Publication date

  2012-02-08

• Fields of study

  Biology, Materials Science

• Identifiers
  DOI 10.4172/2155-952X.S9-001
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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