Crystals of a hammerhead ribozyme.

H. Pley,D. S. Lindes,Camille DeLuca-Flaherty,D. B. McKay

Published 1993 in Journal of Biological Chemistry

ABSTRACT

Hammerhead ribozyme-inhibitor complexes consisting of an RNA "enzyme" strand and a DNA "inhibitor" strand have been crystallized in four different crystal forms. The crystal form that is most attractive for structure determination diffracts to approximately 3.2 A resolution; it is trigonal, space group P3(1)21 or enantiomorph, a = 92.5 A, c = 185.0 A.

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