Diethylhexylphthalate extracted by typical newborn lipid emulsions from polyvinylchloride infusion systems causes significant changes in histology of rabbit liver.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  JPEN - Journal of Parenteral and Enteral Nutrition

• Publication date

  2007-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1177/0148607107031003188PMID 17463143
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparative studies of the hepatic effects of di- and mono-n-octyl phthalates, di-(2-ethylhexyl) phthalate and clofibrate in the rat.

  2009cited by this paper
• Di-(2-ethylhexyl)-phthalate as plasticizer in PVC respiratory tubing systems: indications of hazardous effects on pulmonary function in mechanically ventilated, preterm infants

  2004cited by this paper
• Kinetics of diethylhexyl-phthalate extraction From polyvinylchloride-infusion lines.

  2002cited by this paper
• Polyvinylchloride infusion lines expose infants to large amounts of toxic plasticizers.

  2000cited by this paper
• Methionine Infusion Reproduces Liver Injury of Parenteral Nutrition Cholestasis

  1999cited by this paper
• New approaches to understanding the etiology and treatment of total parenteral nutrition-associated cholestasis.

  1999cited by this paper
• New insight into mechanisms of parenteral nutrition—Associated cholestasis: Role of plant sterols

  1998cited by this paper
• Aluminum in total parenteral nutrition solutions produces portal inflammation in rats.

  1998cited by this paper
• Subchronic toxicity of Di(2-ethylhexyl)phthalate in common marmosets: lack of hepatic peroxisome proliferation, testicular atrophy, or pancreatic acinar cell hyperplasia.

  1998cited by this paper
• BAPS prize lecture: New insight into mechanisms of parenteral nutrition-associated cholestasis: role of plant sterols. British Association of Paediatric Surgeons.

  1998cited by this paper
• Di(2-ethylhexyl) phthalate induces a functional zinc deficiency during pregnancy and teratogenesis that is independent of peroxisome proliferator-activated receptor-alpha.

  1997cited by this paper
• Differential prenatal toxicity of branched phthalate esters in rats.

  1997cited by this paper
• Occupational exposure to polyvinyl chloride as a risk factor for testicular cancer evaluated in a case‐control study

  1997cited by this paper
• Di(2-ethylhexyl) phthalate induces a functional zinc deficiency during pregnancy and teratogenesis that is independent of peroxisome proliferator-activated receptor-α

  1997cited by this paper
• Effects of peroxisome proliferators and/or hypothyroidism on xenobiotic-metabolizing enzymes in rat testis.

  1997cited by this paper
• Long-term total parenteral nutrition and cholecystostomy tube in a rabbit model surgical procedure: management and preliminary results

  1996cited by this paper
• Necrotizing enterocolitis and total parenteral nutrition-associated cholestasis.

  1996cited by this paper
• Hepatocarcinogenic potential of di(2-ethylhexyl)phthalate in rodents and its implications on human risk.

  1996cited by this paper
• Long-term total parenteral nutrition and cholecystostomy tube in a rabbit model surgical procedure: management and preliminary results.

  1996cited by this paper
• Hepatic oxidant injury and glutathione depletion during total parenteral nutrition in weanling rats.

  1996cited by this paper
• Biliary Lithocholate and Cholestasis during and after Total Parenteral Nutrition: An Experimental Study

  1995cited by this paper
• The effect of cholecystokinin-octapeptide on the hepatobiliary dysfunction caused by total parenteral nutrition.

  1995cited by this paper
• Total parenteral nutrition-associated cholestasis: clinical and histopathologic correlation.

  1993cited by this paper
• Total Parenteral Nutrition-Associated Alterations in Hepatobiliary Function and Histology in Rats: Is Light Exposure a Clue?

  1993cited by this paper
• Histopathologic study of cholestasis induced by total parenteral nutrition or intraperitoneal sepsis in rats.

  1991cited by this paper
• Significant Increase of 8‐Hydroxydeoxyguanosine in Liver DNA of Rats Following Short‐term Exposure to the Peroxisome Proliferators Di(2‐ethylhexyl)phthalate and Di(2‐ethylhexyl)adipate

  1990cited by this paper
• Hepatobiliary consequences of parenteral alimentation.

  1990cited by this paper
• Effects of prolonged treatment with phthalate ester on rat liver.

  1990cited by this paper
• Plasticisers and bronchial hyperreactivity.

  1990cited by this paper
• Bacterial Infection: The Main Cause of Acute Cholestasis in Newborn Infants Receiving Short‐Term Parenteral Nutrition

  1989cited by this paper
• A Subacute Rabbit Model for Hepatobiliary Dysfunction During Total Parenteral Nutrition

  1989cited by this paper
• Effects of chronic phthalate exposure on the kidney.

  1988cited by this paper
• Cardiotoxic effects of the plasticizer metabolite, mono (2-ethylhexyl)phthalate (MEHP), on human myocardium.

  1988cited by this paper
• Hypotension and cardiac arrest in rats after infusion of mono(2-ethylhexyl)phthalate (MEHP), a contaminant of stored blood.

  1987cited by this paper
• Metabolic and Peroxisome Proliferation Studies With Di(2-Ethylhexyl)Phthalate in Rats and Monkeys

  1987cited by this paper
• Association of persistent peroxisome proliferation and oxidative injury with hepatocarcinogenicity in female F-344 rats fed di(2-ethylhexyl)phthalate for 2 years.

  1987cited by this paper
• In vitro steady-state levels of hydrogen peroxide after exposure of male F344 rats and female B6C3F1 mice to hepatic peroxisome proliferators.

  1986cited by this paper
• Cholestasis associated with total parenteral nutrition.

  1986cited by this paper
• Effects of repeated intravenous infusions of the plasticizer di-(2-ethylhexyl) phthalate in young male rats

  1985cited by this paper
• Phthalate Esters and Their Effect on the Liver

  1984cited by this paper
• Hepatic failure in infants on total parenteral nutrition (TPN): clinical and histopathologic observations.

  1982cited by this paper
• Effect of KI-(2-ethylhexyl) phthalate on drug metabolism, lipid peroxidation, and sulfhydryl content of rat liver.

  1982cited by this paper
• Serum hepatic enzyme and bilirubin elevations during parenteral nutrition.

  1977cited by this paper
• Effects of a plasticizer leached from polyvinyl chloride on the subhuman primate: a consequence of chronic transfusion therapy.

  1977cited by this paper
• A low-viscosity epoxy resin embedding medium for electron microscopy.

  1969cited by this paper

• Chronic exposure to a mixture of phthalates shifts the white and brown adipose tissue phenotype in female mice.

  2023cites this paper
• Associations of phthalates with NAFLD and liver fibrosis: A nationally representative cross-sectional study from NHANES 2017 to 2018

  2022cites this paper
• Medical devices used in NICU: The main source of plasticisers' exposure of newborns.

  2022cites this paper
• MEHP promotes liver fibrosis by down-regulating STAT5A in BRL-3A hepatocytes.

  2022cites this paper
• Reducing Toxic Phthalate Exposures in Premature Infants

  2021cites this paper
• Urinary concentrations of phthalate metabolites during gestation and intrahepatic cholestasis of pregnancy: a population-based birth cohort study

  2020cites this paper
• Leaching of plasticizers from polyvinylchloride perfusion lines by different lipid emulsions for premature infants under clinical conditions.

  2017cites this paper
• Di (2-Ethylhexyl) Phthalate and Its Role in Developing Cholestasis: An In Vitro Study on Different Liver Cell Types

  2017cites this paper
• Di(2‐ethylhexyl) phthalate (DEHP) [MAK Value Documentation, 2016]

  2017cites this paper
• Methyl bromide / Bromomethane

  2017cites this paper
• Di-(2-ethylhexyl)phthalat (DEHP) [BAT Value Documentation in German language, 2018]

  2016cites this paper
• Phthalates and critically ill neonates: device-related exposures and non-endocrine toxic risks

  2014cites this paper
• In utero exposure to the endocrine disruptor di-(2-ethylhexyl) phthalate induces long-term changes in gene expression in the adult male adrenal gland.

  2014cites this paper
• Phthalates in the NICU: Is it safe?

  2013cites this paper
• Perspectives on alternatives to phthalate plasticized poly(vinyl chloride) in medical devices applications

  2013cites this paper
• Clinical experience with a lipid-free, ready-made parenteral nutrition solution in dogs: 70 cases (2006-2012).

  2013cites this paper
• The effect of temperature on di(2‐ethylhexyl) phthalate leaching from PVC infusion sets exposed to lipid emulsions

  2012influential citation
• A review of alternatives to di (2-ethylhexyl) phthalate-containing medical devices in the neonatal intensive care unit

  2011cites this paper
• Parenteral nutrition-associated conjugated hyperbilirubinemia in hospitalized infants.

  2010cites this paper
• Use of Di(2-Ethylhexyl)Phthalate–Containing Infusion Systems Increases the Risk for Cholestasis

  2009cites this paper
• L’effet à long terme de la nutrition parentérale totale néonatale sur le métabolisme énergétique

  2009influential citation