Anemia is a poor prognostic factor for stage I non-small cell lung cancer (NSCLC) patients treated with Stereotactic Body Radiation Therapy (SBRT)

Highlights • This study reports on the prognostic ability of haematological parameters for the largest known biopsy-proven stage-I medically inoperable cohort treated with SBRT.• After SBRT, the median values of Hb, ALC, ANC and TPC declined whereas the NLR and the PLR increased as compared to pre-SBRT.• Anemia along with other parameters was found to be a poor prognostic factor for local control despite treatment with SBRT to doses of >100 Gy BED10.• Simple and minimally invasive methods like a peripheral blood sample can provide prognostic information even for stage-I NSCLC patients.• Patient, tumor and treatment factors along with molecular markers should be used to create risk stratification models that can guide therapy.

• Publication year

  2019

• Venue

  Clinical and Translational Radiation Oncology

• Publication date

  2019-01-24

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.ctro.2019.01.003PMID 30923751PMCID 6423348
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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