Pruritus secondary to primary biliary cholangitis: a review of the pathophysiology and management with phototherapy

Primary biliary cholangitis (PBC) is an autoimmune hepatobiliary disorder characterized by destruction of liver bile ducts leading to intrahepatic cholestasis. It causes intractable pruritus for which ultraviolet (UV)B phototherapy is an experimental treatment when alternative therapies fail. The pathophysiology of cholestatic itch and the mechanism of action of narrowband UVB in this condition remains poorly understood.

• Publication year

  2019

• Venue

  British Journal of Dermatology

• Publication date

  2019-07-28

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1111/bjd.17933PMID 30920648
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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