Network basis of the dysexecutive and posterior cortical cognitive profiles in Parkinson's disease

S. Lang,A. Hanganu,L. S. Gan,M. Kibreab,N. Auclair-Ouellet,T. Alrazi,M. Ramezani,J. Cheetham,Tracy Hammer,I. Kathol,J. Sarna,O. Monchi

Published 2019 in Movement Disorders

ABSTRACT

The dual syndrome hypothesis of cognitive impairment in PD suggests that two cognitive profiles exist with distinct pathological mechanisms and a differential risk for further cognitive decline. How these profiles relate to network dysfunction has never been explicitly characterized.

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