miR-650 promotes motility of anaplastic thyroid cancer cells by targeting PPP2CA

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Endocrine

• Publication date

  2019-03-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12020-019-01910-3PMID 30927143
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Therapeutic targeting of PP2A.

  2018cited by this paper
• A 22q11.2 amplification in the region encoding microRNA-650 correlates with the epithelial to mesenchymal transition in breast cancer primary cultures of Mexican patients

  2017cited by this paper
• Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies

  2017cited by this paper
• Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population

  2017cited by this paper
• The NF-κB signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression

  2017cited by this paper
• MicroRNAs and metastasis: small RNAs play big roles

  2017cited by this paper
• A step-by-step microRNA guide to cancer development and metastasis

  2017cited by this paper
• MiR-650 represses high-risk non-metastatic colorectal cancer progression via inhibition of AKT2/GSK3β/E-cadherin pathway

  2017cited by this paper
• Microrans in thyroid development , function and tumorigenesis

  2016cited by this paper
• CIP2A is a poor prognostic factor and can be a diagnostic marker in papillary thyroid carcinoma

  2016cited by this paper
• Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia

  2016cited by this paper
• OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer.

  2016cited by this paper
• miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers

  2016cited by this paper
• RNA sequencing identifies crucial genes in papillary thyroid carcinoma (PTC) progression.

  2016cited by this paper
• The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance

  2016cited by this paper
• TWIST1/miR-584/TUSC2 pathway induces resistance to apoptosis in thyroid cancer cells

  2016cited by this paper
• miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma

  2016cited by this paper
• Biologic and Clinical Perspectives on Thyroid Cancer.

  2016cited by this paper
• MicroRNAs in the thyroid.

  2016cited by this paper
• Oncogenic Activity of miR-650 in Prostate Cancer Is Mediated by Suppression of CSR1 Expression.

  2015cited by this paper
• Differentially expressed and activated proteins associated with non small cell lung cancer tissues

  2015cited by this paper
• The proteome of cblC defect: in vivo elucidation of altered cellular pathways in humans

  2015cited by this paper
• Protein phosphatase-2A is down-regulated in patients within clear cell renal cell carcinoma.

  2014cited by this paper
• Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model

  2014cited by this paper
• Insulin‐like growth factor 1 receptor signaling induced by supraphysiological doses of IGF‐1 in human peripheral blood lymphocytes

  2014cited by this paper
• MYLK and MYL9 expression in non-small cell lung cancer identified by bioinformatics analysis of public expression data

  2014cited by this paper
• MiR-421, miR-155 and miR-650: emerging trends of regulation of cancer and apoptosis.

  2014cited by this paper
• MicroRNA-650 expression in glioma is associated with prognosis of patients

  2013cited by this paper
• The secretome signature of colon cancer cell lines

  2013cited by this paper
• MicroRNA-650 Was a Prognostic Factor in Human Lung Adenocarcinoma and Confers the Docetaxel Chemoresistance of Lung Adenocarcinoma Cells via Regulating Bcl-2/Bax Expression

  2013cited by this paper
• The long and short of microRNA.

  2013cited by this paper
• Upregulation of miR‐650 is correlated with down‐regulation of ING4 and progression of hepatocellular carcinoma

  2013cited by this paper
• Protein phosphatase 2A: a target for anticancer therapy.

  2013cited by this paper
• Differential proteomic analysis in human cells subjected to ribosomal stress

  2013cited by this paper
• PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing

  2012cited by this paper
• Overexpression of SET is a recurrent event associated with poor outcome and contributes to protein phosphatase 2A inhibition in acute myeloid leukemia

  2012cited by this paper
• MicroRNA-650 expression is influenced by immunoglobulin gene rearrangement and affects the biology of chronic lymphocytic leukemia.

  2012cited by this paper
• Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650.

  2011cited by this paper
• PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect

  2011cited by this paper
• PP2A in the regulation of cell motility and invasion.

  2011cited by this paper
• Cyclin-dependent kinase 1 expression is inhibited by p16INK4a at the post-transcriptional level through the microRNA pathway

  2011cited by this paper
• Protein Kinases and Phosphatases in the Control of Cell Fate

  2011cited by this paper
• Role of NF-kappaB in thyroid cancer.

  2010cited by this paper
• MicroRNA-650 targets ING4 to promote gastric cancer tumorigenicity.

  2010cited by this paper
• MicroRNAs: Target Recognition and Regulatory Functions

  2009cited by this paper
• Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.

  2008cited by this paper
• Multiple pathways regulated by the tumor suppressor PP2A in transformation.

  2008cited by this paper
• Selection of Protein Phosphatase 2A Regulatory Subunits Is Mediated by the C Terminus of the Catalytic Subunit*

  2007cited by this paper
• The Role of PP2A A Subunits in Tumor Suppression

  2007cited by this paper
• Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling.

  2001cited by this paper

• Novel Biological Strategies for Melanoma Therapy: A Focus on lncRNAs and Their Targeting

  2025cites this paper
• The Long Non-Coding RNA linc01105 Inhibits Gastric Cancer Growth and Metastasis by Regulating the miR-650/TCEA3 Axis.

  2025cites this paper
• miR-331-5p Affects Motility of Thyroid Cancer Cell Lines and Regulates BID Expression

  2024cites this paper
• MicroRNA-650 promotes melanoma metastasis via targeting inhibitor of growth family member 4

  2024cites this paper
• Restoration of miR-650 leads to down-regulation of KISS1, a possible route involved in overcoming 5-FU resistance and induction of apoptosis in CRC cells in-vitro

  2023cites this paper
• Antitumor mechanism of Saikosaponin A in the Xiaoying Sanjie Decoction for treatment of anaplastic thyroid cancer by network pharmacology analysis and experiments in vitro and in vivo.

  2023cites this paper
• Unveiling the protein signature of the human osteosarcoma 3AB-OS cancer stem cell line.

  2023cites this paper
• LINC01002 Targets miR-650/FLNA Pathway to Suppress Prostate Cancer Progression

  2023cites this paper
• Epi-miRNAs: Regulators of the Histone Modification Machinery in Human Cancer

  2022cites this paper
• Remifentanil reduces the proliferation, migration and invasion of HCC cells via lncRNA NBR2/miR‐650/TIMP3 axis

  2022cites this paper
• PP2Acα regulates epidermal cell proliferation via the EGFR/AKT/mTOR pathway in psoriasis‐like skin lesions caused by PPP2CA deficiency

  2022cites this paper
• Functions and underlying mechanisms of miR-650 in human cancers

  2022influential citation
• Discovering Common miRNA Signatures Underlying Female-Specific Cancers via a Machine Learning Approach Driven by the Cancer Hallmark ERBB

  2022cites this paper
• Identification of LncRNA CARD8-AS1 as a Potential Prognostic Biomarker Associated With Progression of Lung Adenocarcinoma

  2022cites this paper
• Knockdown of circ_0025908 inhibits proliferation, migration, invasion, and inflammation while stimulates apoptosis in fibroblast-like synoviocytes by regulating miR-650-dependent SCUBE2

  2022cites this paper
• Anti-Virulence Potential of a Chionodracine-Derived Peptide against Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates from Cystic Fibrosis Patients

  2022cites this paper
• LncRNA POU3F3 Contributes to Dacarbazine Resistance of Human Melanoma Through the MiR-650/MGMT Axis

  2021cites this paper
• LncRNA MCTP1-AS1 Regulates EMT Process in Endometrial Cancer by Targeting the miR-650/SMAD7 Axis

  2021cites this paper
• Circular RNA Circ_0067934 Attenuates Ferroptosis of Thyroid Cancer Cells by miR-545-3p/SLC7A11 Signaling

  2021cites this paper
• Potential Role and Clinical Value of PPP2CA in Hepatocellular Carcinoma

  2021cites this paper
• Long Non-coding RNA RP11-395G23.3 Acts as a Competing Endogenous RNA of miR-124-3p to Regulate ROR1 in Anaplastic Thyroid Carcinoma

  2021cites this paper
• Benzo[a]pyrene stimulates miR-650 expression to promote the pathogenesis of fatty liver disease and hepatocellular carcinoma via SOCS3/JAK/STAT3 cascades

  2021cites this paper
• miR‐381‐3p attenuates doxorubicin resistance in human anaplastic thyroid carcinoma via targeting homeobox A9

  2021cites this paper
• Identification of key miRNAs and targeted genes involved in the progression of oral squamous cell carcinoma

  2021cites this paper
• Poorly Differentiated and Anaplastic Thyroid Cancer: Insights into Genomics, Microenvironment and New Drugs

  2021cites this paper
• The promotion of precise diagnosis and treatment of thyroid cancer by mass spectrometry-based high throughput proteomics technologies

  2020influential citation
• Upregulation of microRNA-650 by PBX1 is correlated with the development of Helicobacter pylori-associated gastric carcinoma.

  2020cites this paper
• A Bioinformatic Pipeline Places STAT5A as a miR-650 Target in Poorly Differentiated Aggressive Breast Cancer

  2020cites this paper
• miR-592 acts as an oncogene and promotes medullary thyroid cancer tumorigenesis by targeting cyclin-dependent kinase 8

  2020cites this paper
• miR-622 is a novel potential biomarker of breast carcinoma and impairs motility of breast cancer cells through targeting NUAK1 kinase

  2020cites this paper
• Axin1 inhibits proliferation, invasion, migration and EMT of hepatocellular carcinoma by targeting miR-650.

  2020cites this paper