Differential expression of the α2-macroglobulin receptor and the receptor associated protein in normal human endometrium and endometrial carcinoma

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Molecular Human Reproduction

• Publication date

  2000-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/MOLEHR/6.10.921
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• The level of urokinase-type plasminogen activator receptor is increased in serum of ovarian cancer patients.

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  1981cited by this paper
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