Uterine leiomyoma in chimpanzee (Pan troglodytes)

Uma chimpanze de 22 anos de idade foi necropsiada com historico clinico de anorexia, vomitos frequentes e desidratacao consequentes a gastrite iatrogenica. Macroscopicamente, o utero apresentava-se aumentado de volume, com o lumen totalmente ocluido por nodulos firmes, esbranquicados e coalescentes que se estendiam para o miometrio. Histologicamente, os nodulos eram constituidos por leiomiocitos bem diferenciados dispostos em varias direcoes e com coloracao caracteristica pelo tricromio de Gomori e Masson. Pela imunoistoquimica, as celulas neoplasicas apresentavam marcacao forte e difusa de receptores para progesterona e estrogeno, assim como de actina alfa de musculo liso. Algumas celulas neoplasicas e o estroma apresentavam marcacao para vimentina e poucas celulas neoplasicas foram positivas para MIB-1. Com base nas caracteristicas mosrfologicas e imunoistoquimicas foi firmado o diagnostico de leiomioma uterino.

• Publication year

  2006

• Venue

  Arquivo Brasileiro De Medicina Veterinaria E Zootecnia

• Publication date

  2006-02-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1590/S0102-09352006000100020
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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