Vestibular signal processing in a subject with somatosensory deafferentation: The case of sitting posture

BackgroundThe vestibular system of the inner ear provides information about head translation/rotation in space and about the orientation of the head with respect to the gravitoinertial vector. It also largely contributes to the control of posture through vestibulospinal pathways. Testing an individual severely deprived of somatosensory information below the nose, we investigated if equilibrium can be maintained while seated on the sole basis of this information.ResultsAlthough she was unstable, the deafferented subject (DS) was able to remain seated with the eyes closed in the absence of feet, arm and back supports. However, with the head unconsciously rotated towards the left or right shoulder, the DS's instability markedly increased. Small electrical stimulations of the vestibular apparatus produced large body tilts in the DS contrary to control subjects who did not show clear postural responses to the stimulations.ConclusionThe results of the present experiment show that in the lack of vision and somatosensory information, vestibular signal processing allows the maintenance of an active sitting posture (i.e. without back or side rests). When head orientation changes with respect to the trunk, in the absence of vision, the lack of cervical information prevents the transformation of the head-centered vestibular information into a trunk-centered frame of reference of body motion. For the normal subjects, this latter frame of reference enables proper postural adjustments through vestibular signal processing, irrespectively of the orientation of the head with respect to the trunk.

• Publication year

  2007

• Venue

  BMC Neurology

• Publication date

  2007-08-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1186/1471-2377-7-25PMID 17727717PMCID 2014758
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Internally driven control of reaching movements: a study on a proprioceptively deafferented subject.

  2006cited by this paper
• Neural bases of postural control.

  2006cited by this paper
• Direction-specific postural instability in subjects with Parkinson's disease.

  2005cited by this paper
• Aging-induced shifts from a reliance on sensory input to muscle cocontraction during balanced standing.

  2004cited by this paper
• Human perception of horizontal trunk and head rotation in space during vestibular and neck stimulation

  2004cited by this paper
• Evidence for reflex and perceptual vestibular contributions to postural control

  2004cited by this paper
• Multiple Reference Frames for Motion in the Primate Cerebellum

  2004cited by this paper
• Postural adjustments in sitting humans following external perturbations: muscle activity and kinematics

  2004cited by this paper
• Probing the human vestibular system with galvanic stimulation.

  2004influential reference
• Trunk position influences vestibular responses of fastigial nucleus neurons in the alert monkey.

  2004cited by this paper
• Reference systems for coding spatial information in normal subjects and a deafferented patient

  2004cited by this paper
• Production and perception of grip force without proprioception: is there a sense of effort in deafferented subjects?

  2003cited by this paper
• The Vestibulospinal Reflex in Humans: Effects on Paraspinal Muscle Activity

  2003cited by this paper
• Modulation of afferent inflow during the control of balancing tasks using the lower limbs.

  2003cited by this paper
• Effects of galvanic vestibular stimulation on human posture and perception while standing

  2003cited by this paper
• Vestibular actions on back and lower limb muscles during postural tasks in man

  2003cited by this paper
• Proprioception and locomotor disorders

  2002cited by this paper
• Vestibular-evoked postural responses in the absence of somatosensory information.

  2002influential reference
• Triggering of balance corrections and compensatory strategies in a patient with total leg proprioceptive loss

  2001cited by this paper
• Proprioceptive input overrides vestibulo-spinal drive during human locomotion

  2001cited by this paper
• How changes in vestibular and visual reference frames combine to modify body orientation in space

  2001cited by this paper
• Somatosensory loss increases vestibulospinal sensitivity.

  2001cited by this paper
• Afferent diversity and the organization of central vestibular pathways

  2000cited by this paper
• Postural control of trunk during unstable sitting.

  2000cited by this paper
• The neural representation of postural control in humans.

  2000cited by this paper
• Effect of gaze on postural responses to neck proprioceptive and vestibular stimulation in humans

  1999cited by this paper
• Role of the feedforward command and reafferent information in the coordination of a passing prehension task

  1999cited by this paper
• Human body‐segment tilts induced by galvanic stimulation: a vestibularly driven balance protection mechanism.

  1997cited by this paper
• Gait of a deafferented subject without large myelinated sensory fibers below the neck

  1996cited by this paper
• Postural adjustments associated with different unloadings of the forearm: effects of proprioceptive and cutaneous afferent deprivation.

  1995cited by this paper
• Effect of galvanic vestibular stimulation on human postural responses during support surface translations.

  1995cited by this paper
• Perception of passive whole-body rotations in the absence of neck and body proprioception.

  1995cited by this paper
• Weight judgment. The discrimination capacity of a deafferented subject.

  1995cited by this paper
• Task‐dependent reflex responses and movement illusions evoked by galvanic vestibular stimulation in standing humans.

  1994cited by this paper
• Myogenic potentials generated by a click-evoked vestibulocollic reflex.

  1994cited by this paper
• The role of proprioceptive information for the production of isometric forces and for handwriting tasks.

  1993cited by this paper
• Loss of proprioception produces deficits in interjoint coordination.

  1993cited by this paper
• Pride and a Daily Marathon

  1992cited by this paper
• Postural strategies associated with somatosensory and vestibular loss

  1990cited by this paper
• Relation between discharge regularity and responses to externally applied galvanic currents in vestibular nerve afferents of the squirrel monkey.

  1984cited by this paper
• Cervical control of posture and movements.

  1979cited by this paper
• Ataxia and nystagmus induced by injection of local anesthetics in the neck

  1977cited by this paper
• Influence of head position and proprioceptive cues on short latency postural reflexes evoked by galvanic stimulation of the human labyrinth.

  1974influential reference
• Role of eye and neck proprioceptive mechanisms in body orientation and motor coordination.

  1961cited by this paper

• Bed rest impairs the vestibular control of balance

  2024cites this paper
• A novel method of assessing balance and postural sway in patients with hypermobile Ehlers-Danlos syndrome

  2023cites this paper
• Cortical facilitation of somatosensory inputs using gravity-related tactile information in humans with vestibular hypofunction.

  2023cites this paper
• Cortical facilitation of somatosensory inputs using gravity-related tactile information in patients with bilateral vestibular loss

  2022cites this paper
• Postural mechanisms in moderate-to-severe cerebral palsy.

  2021cites this paper
• Perceptual-motor styles

  2021cites this paper
• Motor Responses of Lumbar Erector Spinae Induced by Electrical Vestibular Stimulation in Seated Participants

  2021cites this paper
• Influence of Visual Dependence on Inter-Segmental Coordination during Upright Stance in Cerebral Palsy

  2020cites this paper
• Independent Early and Late Sensory Processes for Proprioceptive Integration When Planning a Step.

  2019cites this paper
• Somatosensory Loss Influences the Adoption of Self-Centered Versus Decentered Perspectives

  2019cites this paper
• Human Postural Control

  2018cites this paper
• Pilotstudie: Bestimmung der subjektiven Rumpfvertikalen in lotrechter Kopfposition

  2018cites this paper
• [Pilot study: Determination of the subjective trunk vertical in upright head position].

  2018cites this paper
• The relationship between whole-body motion and upper limb control for reaching and balance

  2017cites this paper
• Vestibular feedback maintains reaching accuracy during body movement

  2016influential citation
• Do Visual and Vestibular Inputs Compensate for Somatosensory Loss in the Perception of Spatial Orientation? Insights from a Deafferented Patient

  2016cites this paper
• Effect of short-term application of kinesio tape on the flexion-relaxation phenomenon, trunk postural control and trunk repositioning in healthy females

  2016cites this paper
• Integration of Vestibular and Cervical Information to Code Trunk Motion

  2015cites this paper
• Prediction in the Vestibular Control of Arm Movements.

  2015cites this paper
• Contributions des voies vestibulospinale et corticospinale au contrôle des mouvements du bras

  2015cites this paper
• Estimate of body motion during voluntary body sway movements.

  2014cites this paper
• Do Gravity-Related Sensory Information Enable the Enhancement of Cortical Proprioceptive Inputs When Planning a Step in Microgravity?

  2014cites this paper
• Sensory reweighting in controls and stroke patients.

  2013cites this paper
• A task-dependent effect of memory and hand-target on proprioceptive localization.

  2012cites this paper
• task-dependent effect of memory and hand-target on proprioceptive ocalization tephanie

  2012cites this paper
• Prediction of the body rotation-induced torques on the arm during reaching movements: evidence from a proprioceptively deafferented subject.

  2011cites this paper
• Age-related decline in sensory processing for locomotion and interception.

  2011cites this paper
• Vestibular and proprioceptive estimation of imposed rotation and spatial updating in standing subjects.

  2011cites this paper
• Modulation of proprioceptive inXow when initiating a step inXuences postural adjustments

  2010cites this paper
• Identification of frontal plane stance control mechanisms for humans

  2010cites this paper
• Modulation of proprioceptive inflow when initiating a step influences postural adjustments

  2010cites this paper
• Force-field adaptation without proprioception: can vision be used to model limb dynamics?

  2010cites this paper
• Insights into the control of arm movement during body motion as revealed by EMG analyses.

  2010cites this paper
• Head stability during quiet sitting in children with cerebral palsy: effect of vision and trunk support

  2010cites this paper
• Internal models and neural computation in the vestibular system

  2009cites this paper
• Multimodal Integration in Rostral Fastigial Nucleus Provides an Estimate of Body Movement

  2009cites this paper
• Contribution of sensorimotor integration to spinal stabilization in humans.

  2009cites this paper
• Author ' s personal copy

  2008cites this paper