Book Review: On the Function of Dendritic Spines

No abstract is available for this paper.

• Publication year

  2001

• Venue

  The Neuroscientist

• Publication date

  2001-10-01

• Fields of study

  Biology

• Identifiers
  DOI 10.1177/107385840100700508
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• NMDA Receptor-Mediated Subthreshold Ca2+ Signals in Spines of Hippocampal Neurons

  2000cited by this paper
• Regulation of Spine Calcium Dynamics by Rapid Spine Motility

  2000cited by this paper
• Mechanisms of Calcium Decay Kinetics in Hippocampal Spines: Role of Spine Calcium Pumps and Calcium Diffusion through the Spine Neck in Biochemical Compartmentalization

  2000cited by this paper
• Calcium dynamics associated with action potentials in single nerve terminals of pyramidal cells in layer 2/3 of the young rat neocortex

  2000cited by this paper
• From form to function: calcium compartmentalization in dendritic spines

  2000cited by this paper
• Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo

  2000cited by this paper
• Regulation of dendritic spine morphology by the rho family of small GTPases: antagonistic roles of Rac and Rho.

  2000cited by this paper
• Quantitative fine-structural analysis of olfactory cortical synapses.

  1999cited by this paper
• Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines.

  1999cited by this paper
• Mechanisms of Calcium Influx into Hippocampal Spines: Heterogeneity among Spines, Coincidence Detection by NMDA Receptors, and Optical Quantal Analysis

  1999cited by this paper
• Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated

  1999cited by this paper
• Developmental regulation of spine motility in the mammalian central nervous system.

  1999cited by this paper
• NMDA receptors amplify calcium influx into dendritic spines during associative pre- and postsynaptic activation

  1998cited by this paper
• Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials.

  1998cited by this paper
• Dendritic spines

  1998cited by this paper
• Long-term plasticity at excitatory synapses on aspinous interneurons in area CA1 lacks synaptic specificity.

  1998cited by this paper
• Rapid actin-based plasticity in dendritic spines.

  1998cited by this paper
• Stabilization of dendritic arbor structure in vivo by CaMKII.

  1998cited by this paper
• The dendritic spine: a multifunctional integrative unit.

  1996influential reference
• Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines

  1996cited by this paper
• Direct Measurement of Coupling Between Dendritic Spines and Shafts

  1996cited by this paper
• Regulation of hippocampal transmitter release during development and long-term potentiation.

  1995cited by this paper
• Dendritic spines as basic functional units of neuronal integration

  1995influential reference
• An evaluation of causes for unreliability of synaptic transmission.

  1994cited by this paper
• Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function.

  1994cited by this paper
• Synaptic plasticity: LTP and LTD.

  1994cited by this paper
• The function of dendritic spines: devices subserving biochemical rather than electrical compartmentalization

  1993influential reference
• Dendritic spines: convergence of theory and experiment.

  1992cited by this paper
• Calcium gradients and buffers in bovine chromaffin cells.

  1992cited by this paper
• Independent regulation of calcium revealed by imaging dendritic spines

  1991cited by this paper
• Dendritic spines as individual neuronal compartments for synaptic Ca2+ responses

  1991cited by this paper
• Presynaptic mechanism for long-term potentiation in the hippocampus

  1990cited by this paper
• A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

  1989cited by this paper
• Analog VLSI and neural systems

  1989cited by this paper
• Electrically coupled but chemically isolated synapses: dendritic spines and calcium in a rule for synaptic modification.

  1988influential reference
• Feasibility of long-term storage of graded information by the Ca2+/calmodulin-dependent protein kinase molecules of the postsynaptic density.

  1988cited by this paper
• Evidence for interlaminar inhibitory circuits in the striate cortex of the cat

  1987cited by this paper
• Logic operations are properties of computer-simulated interactions between excitable dendritic spines.

  1987cited by this paper
• Regulation of brain type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: a Ca2+-triggered molecular switch.

  1986cited by this paper
• Hippocampal long-term potentiation is induced by pairing single afferent volleys with intracellularly injected depolarizing current pulses.

  1986cited by this paper
• A mechanism for memory storage insensitive to molecular turnover: a bistable autophosphorylating kinase.

  1985cited by this paper
• Distinct forebrain and cerebellar isozymes of type II Ca2+/calmodulin-dependent protein kinase associate differently with the postsynaptic density fraction.

  1985cited by this paper
• Signal enhancement in distal cortical dendrites by means of interactions between active dendritic spines.

  1985cited by this paper
• Dendritic spines: role of active membrane in modulating synaptic efficacy.

  1985cited by this paper
• Associative long-term potentiation in hippocampal slices.

  1983cited by this paper
• Long-term potentiation of the perforant path in vivo is associated with increased glutamate release

  1982cited by this paper
• The axo-axonic interneuron in the cerebral cortex of the rat, cat and monkey.

  1982cited by this paper
• Neural networks and physical systems with emergent collective computational abilities.

  1982cited by this paper
• Dendritic spines only connect

  1981cited by this paper
• The Synaptic Organization of the Brain

  1980cited by this paper
• Synapses as associative memory elements in the hippocampal formation.

  1979cited by this paper
• Electric current flow in excitable cells

  1975cited by this paper
• Evidence for Presynaptic Dendrites and a Proposal for their Mechanism of Action

  1971cited by this paper
• The small pyramidal neuron of the rat cerebral cortex. The perikaryon, dendrites and spines.

  1970cited by this paper
• Morphological variations in the dendritic spines of the neocortex.

  1969cited by this paper
• Synaptic patterns on different cell types in the different laminae of the cat visual cortex. An electron microscope study.

  1968influential reference
• Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb.

  1968cited by this paper
• Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study.

  1959cited by this paper
• Electron Microscopy of Synaptic Contacts on Dendrite Spines of the Cerebral Cortex

  1959cited by this paper
• SYNAPSES IN THE CENTRAL NERVOUS SYSTEM

  1956cited by this paper
• SOME FEATURES OF THE SUBMICROSCOPIC MORPHOLOGY OF SYNAPSES IN FROG AND EARTHWORM

  1955cited by this paper
• Cortical neurons with particular reference to the apical dendrites.

  1952cited by this paper
• Neue Darstellung vom histologischen Bau des Centralnervensystems

  1894cited by this paper
• Estructura de los centros nerviosos de las Aves

  1888cited by this paper
• THE CEREBELLAR CORTEX

  1883influential reference
• The Croonian lecture.—La fine structure des centres nerveux

  year unknowncited by this paper
• Significación fisiológica de las expansiones protoplasmáticas y nerviosas de las células de la sustancia gris

  year unknowninfluential reference

• Principles for Dendritic Spine Size and Density in Human and Mouse Cortical Pyramidal Neurons

  2025cites this paper
• Functional and morphological adaptation of medial prefrontal corticotropin releasing factor receptor 1-expressing neurons in male mice following chronic ethanol exposure

  2024cites this paper
• Evaluation of dendrite morphology in Wistar and genetic absence epileptic rats

  2024cites this paper
• Sevoflurane exposure may cause dysplasia of dendritic spines and result in fine motor dysfunction in developing mouse through the PI3K/AKT/mTOR pathway

  2022cites this paper
• Electrical recordings from dendritic spines of adult mouse hippocampus and effect of the actin cytoskeleton

  2022cites this paper
• Oxidative stress, the immune response, synaptic plasticity, and cognition in transgenic models of Alzheimer disease.

  2021cites this paper
• Requirements of Postnatal proBDNF in the Hippocampus for Spatial Memory Consolidation and Neural Function

  2021cites this paper
• LIM-Kinases in Synaptic Plasticity, Memory, and Brain Diseases

  2021cites this paper
• C9orf72 hexanucleotide repeat expansion leads to altered neuronal and dendritic spine morphology and synaptic dysfunction.

  2021cites this paper
• Neurotransmitters, neuromodulators, synapses

  2021cites this paper
• Lack of change in CA1 dendritic spine density or clustering in rats following training on a radial-arm maze task

  2020cites this paper
• Mecanismos de codificación y procesamiento de información en redes basadas en firmas neuronales

  2020cites this paper
• Electrodiffusion models of synaptic potentials in dendritic spines

  2019cites this paper
• Src-mediated phosphorylation of βPix-b regulates dendritic spine morphogenesis

  2019cites this paper
• Oxidative stress, the immune response, synaptic plasticity, and cognition in transgenic models of Alzheimer disease.

  2019cites this paper
• Cdk5 Is Essential for Amphetamine to Increase Dendritic Spine Density in Hippocampal Pyramidal Neurons

  2017cites this paper
• Structural and functional plasticity of dendritic spines – root or result of behavior?

  2017cites this paper
• Reelin Regulates the Maturation of Dendritic Spines, Synaptogenesis and Glial Ensheathment of Newborn Granule Cells

  2016cites this paper
• The Plasminogen Activation System Promotes Dendritic Spine Recovery and Improvement in Neurological Function After an Ischemic Stroke

  2016cites this paper
• The phospholipid-binding protein SESTD1 negatively regulates dendritic spine density by interfering with Rac1-Trio8 signaling pathway

  2015cites this paper
• Dendritic spine morphology and dynamics in health and disease

  2015cites this paper
• Dendritic spine dysgenesis contributes to hyperreflexia after spinal cord injury.

  2015cites this paper
• The discovery of dendritic spines by Cajal

  2015cites this paper
• Methods for studying the zebrafish brain: past, present and future

  2015cites this paper
• FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons

  2015cites this paper
• The Relevance of Subplate Modifications to Connectivity in the Cerebral Cortex of Individuals with Autism Spectrum Disorders

  2015cites this paper
• Effects of long-term agomelatine treatment on the cognitive performance and hippocampal plasticity of adult rats

  2015cites this paper
• Repeated Administrations of Human Umbilical Cord Blood Cells Improve Disease Outcomes in a Mouse Model of Sanfilippo Syndrome Type III B

  2014cites this paper
• Role of Reelin in synaptogenesis and synaptic stabilization in the adult brain

  2014influential citation
• The role of dendritic inhibition in shaping the plasticity of excitatory synapses

  2013cites this paper
• Microglia: a new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research.

  2013cites this paper
• SNX26, a GTPase-activating Protein for Cdc42, Interacts with PSD-95 Protein and Is Involved in Activity-dependent Dendritic Spine Formation in Mature Neurons*

  2013cites this paper
• Diabetes exacerbates the loss of basilar dendritic spines after ischemic stroke

  2013cites this paper
• Differential striatal spine pathology in Parkinson's disease and cocaine addiction: a key role of dopamine?

  2013cites this paper
• Regulation of the Ras Pathway by Neurofibromin in Dendritic Spines

  2012cites this paper
• Amyloid plaque formation precedes dendritic spine loss

  2012cites this paper
• Effect of brain‐derived neurotrophic factor haploinsufficiency on stress‐induced remodeling of hippocampal neurons

  2011cites this paper
• Control of synapse development and plasticity by Rho GTPase regulatory proteins.

  2011cites this paper
• Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways.

  2011cites this paper
• The role of insulin receptor signaling in synaptic plasticity and cognitive function.

  2010cites this paper
• Dendritic spine remodeling after spinal cord injury alters neuronal signal processing.

  2009cites this paper
• Efecto del Estrés crónico sobre la remodelación dendrítica en la región CA3 del hipocampo Effect of chronic stress on the dendritic remodeling in the region CA3 hippocampal

  2009cites this paper
• Interactions between drebrin and Ras regulate dendritic spine plasticity

  2008cites this paper
• Molecular mechanisms of stress-induced prefrontal cortical impairment: implications for mental illness.

  2008cites this paper
• Dendritic excitability and synaptic plasticity.

  2008cites this paper
• Activity-Dependent Structural Plasticity of Dendritic Spines

  2008cites this paper
• Rapid Morphologic Plasticity of Peri-Infarct Dendritic Spines After Focal Ischemic Stroke

  2008cites this paper
• LTP and adaptation to inactivity: overlapping mechanisms and implications for metaplasticity.

  2007cites this paper
• What can Artificial Intelligence get from Neuroscience

  2007cites this paper
• ESTUDO SOBRE A DENSIDADE DE ESPINHOS DENDRÍTICOS DE NEURÔNIOS DA AMÍGDALA MEDIAL PÓSTERO-DORSAL DE RATOS EM DIFERENTES CONDIÇÕES EXPERIMENTAIS

  2006cites this paper
• What Can AI Get from Neuroscience?

  2006cites this paper
• Spatio-temporal filtering properties of a dendritic cable with active spines: A modeling study in the spike-diffuse-spike framework

  2006cites this paper
• Density and morphology of dendritic spines in mouse neocortex.

  2006cites this paper
• Inter- and intra-laminar connections of pyramidal cells in the neocortex.

  2005cites this paper
• Genesis of dendritic spines: insights from ultrastructural and imaging studies

  2004cites this paper
• Electrophysiological classes of neocortical neurons

  2004cites this paper
• Regulation of dendritic spine motility and stability by Rac1 and Rho kinase: evidence for two forms of spine motility.

  2004cites this paper
• Developmental regulation of spine and filopodial motility in primary visual cortex: reduced effects of activity and sensory deprivation.

  2004cites this paper
• Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones

  2003cites this paper
• Calcium microdomains in aspiny dendrites.

  2003cites this paper
• The role of dendritic spines: comparing the complex with the simple.

  2002cites this paper
• Cortical area and species differences in dendritic spine morphology

  2002cites this paper
• Selectivity in the inter-laminar connections made by neocortical neurones

  2002cites this paper