Calcium/Calmodulin‐Dependent Protein Kinase II Activity in Focal Ischemia With Reperfusion in Rats

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Stroke

• Publication date

  1994-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.STR.25.2.466PMID 8303758
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neuronal Protection and Preservation of Calcium/Calmodulin-Dependent Protein Kinase II and Protein Kinase C Activity by Dextrorphan Treatment in Global Ischemia

  1993cited by this paper
• Threshold of Calcium Disturbances After Focal Cerebral Ischemia in Rats: Implications of the Window of Therapeutic Opportunity

  1993cited by this paper
• Ischemia‐Induced Translocation of Ca2+/Calmodulin‐Dependent Protein Kinase II: Potential Role in Neuronal Damage

  1992cited by this paper
• Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice.

  1992cited by this paper
• Global Forebrain Ischemia Results in Decreased Immunoreactivity of Calcium/Calmodulin-Dependent Protein Kinase II

  1992cited by this paper
• Regional and Temporal Alterations in Ca2+/Calmodulin‐Dependent Protein Kinase II and Calcineurin in the Hippocampus of Rat Brain After Transient Forebrain Ischemia

  1992cited by this paper
• Global Forebrain Ischemia Induces a Posttranslational Modification of Multifunctional Calcium‐ and Calmodulin‐Dependent Kinase II

  1992cited by this paper
• Regulation of Cl- channels by multifunctional CaM kinase.

  1991cited by this paper
• Serine/threonine kinases in the nervous system.

  1991cited by this paper
• Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia.

  1991cited by this paper
• Protein kinases and phosphorylation in neurologic disorders and cell death.

  1991cited by this paper
• Calcium and ischemic injury.

  1991cited by this paper
• The excitotoxin hypothesis in relation to cerebral ischemia.

  1991cited by this paper
• Ca2+/calmodulin kinase is activated by the phosphatidylinositol signaling pathway and becomes Ca2(+)-independent in PC12 cells.

  1990cited by this paper
• Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes

  1990cited by this paper
• Protein phosphorylation during ischemia.

  1990cited by this paper
• Cerebral hypoxia: some new approaches and unanswered questions

  1990cited by this paper
• Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils.

  1990cited by this paper
• Effects of synapsin I and calcium/calmodulin-dependent protein kinase II on spontaneous neurotransmitter release in the squid giant synapse.

  1990cited by this paper
• Possible mechanisms limiting N-methyl-D-aspartate receptor overactivation and the therapeutic efficacy of N-methyl-D-aspartate antagonists.

  1990cited by this paper
• Structure and regulation of type II calcium/calmodulin-dependent protein kinase in central nervous system neurons.

  1990cited by this paper
• Multifunctional Ca2+/calmodulin-dependent protein kinase: domain structure and regulation.

  1989cited by this paper
• Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

  1989influential reference
• Immunohistochemical Determination of Calcium—Calmodulin Binding Predicts Neuronal Damage after Global Ischemia

  1989cited by this paper
• Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP.

  1989cited by this paper
• Functional analysis of Ca2+/calmodulin-dependent protein kinase II expressed in bacteria.

  1989cited by this paper
• Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

  1988cited by this paper
• Cerebral ischemia decreases endogenous calcium-dependent protein phosphorylation in gerbil brain.

  1988cited by this paper
• Historical Overview

  1988cited by this paper
• Caldueemedlated neurotoxidty: relat ship to specific channel types and role in isdemic damage

  1988cited by this paper
• Excitatory amino acids activate calpain I and induce structural protein breakdown in vivo.

  1988cited by this paper
• Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury

  1987cited by this paper
• Inciting excitotoxic cytocide among central neurons.

  1986cited by this paper
• Glutamate and the pathophysiology of hypoxic–ischemic brain damage

  1986cited by this paper
• Calcium and ischemic injury.

  1986cited by this paper
• The neurotoxicity of excitatory amino acids is produced by passive chloride influx

  1985cited by this paper
• Brain Cortical Fatty Acids and Phospholipids During and Following Complete and Severe Incomplete Ischemia

  1982cited by this paper
• Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid‐Induced Brain Swelling

  1980cited by this paper
• Calcium dependence of toxic cell death: a final common pathway.

  1979cited by this paper

• International Union of Basic and Clinical Pharmacology. CXX. γ-Hydroxybutyrate protein targets in the mammalian brain-beyond classic receptors.

  2025cites this paper
• Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases

  2024cites this paper
• Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases

  2023cites this paper
• CaMKIIα as a Promising Drug Target for Ischemic Grey Matter

  2022cites this paper
• The CaMKIIα hub ligand Ph-HTBA promotes neuroprotection after focal ischemic stroke by a distinct molecular interaction.

  2022cites this paper
• Exercise, CaMKII, and type 2 diabetes

  2021cites this paper
• TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury

  2020cites this paper
• TRPM7 Mediates Neuronal Cell Death Upstream of Calcium/Calmodulin-Dependent Protein Kinase II and Calcineurin Mechanism in Neonatal Hypoxic-Ischemic Brain Injury

  2020cites this paper
• Proteomics of the mediodorsal thalamic nucleus of rats with stress-induced gastric ulcer

  2019cites this paper
• Constitutive regulation of the glutamate/aspartate transporter EAAT1 by Calcium‐Calmodulin‐Dependent Protein Kinase II

  2017cites this paper
• Paeoniflorin Attenuates Cerebral Ischemia-Induced Injury by Regulating Ca2+/CaMKII/CREB Signaling Pathway

  2017cites this paper
• Long non-coding RNA C2dat1 regulates CaMKIIδ expression to promote neuronal survival through the NF-κB signaling pathway following cerebral ischemia

  2016cites this paper
• Ischemic preconditioning protects the brain against injury via inhibiting CaMKII-nNOS signaling pathway.

  2016cites this paper
• CaMKII regulation of astrocytic glutamate uptake

  2016cites this paper
• Beneficial Effects of a CaMKIIα Inhibitor TatCN21 Peptide in Global Cerebral Ischemia

  2016cites this paper
• Edaravone Enhances Brain-Derived Neurotrophic Factor Production in the Ischemic Mouse Brain

  2015cites this paper
• Excitotoxic Insult Results in a Long-Lasting Activation of CaMKIIα and Mitochondrial Damage in Living Hippocampal Neurons

  2015cites this paper
• CaMKII: a molecular substrate for synaptic plasticity and memory.

  2014cites this paper
• 3,5,6,7,8,3',4'-Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse model.

  2014cites this paper
• p600 stabilizes microtubules to prevent the aggregation of CaMKIIα during photoconductive stimulation

  2014cites this paper
• Loss of Calcium/Calmodulin-dependent Protein Kinase II Activity in Cortical Astrocytes Decreases Glutamate Uptake and Induces Neurotoxic Release of ATP*

  2013influential citation
• Induces Neurotoxic Release of ATP Astrocytes Decreases Glutamate Uptake Protein Kinase II Activity in Cortical Loss of Calcium / Calmodulin-dependent Molecular Bases of Disease :

  2013influential citation
• Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Inhibition Induces Neurotoxicity via Dysregulation of Glutamate/Calcium Signaling and Hyperexcitability*

  2012influential citation
• The effects of CaMKII signaling on neuronal viability

  2012influential citation
• Excitotoxic neuroprotection and vulnerability with CaMKII inhibition.

  2011influential citation
• DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke.

  2010cites this paper
• Differential regulation by ATP versus ADP further links CaMKII aggregation to ischemic conditions

  2009cites this paper
• Protein Kinase C-γ and Calcium/Calmodulin-Dependent Protein Kinase II-α Are Persistently Translocated to Cell Membranes of the Rat Brain during and after Middle Cerebral Artery Occlusion

  2004cites this paper
• Protein kinase C-gamma and calcium/calmodulin-dependent protein kinase II-alpha are persistently translocated to cell membranes of the rat brain during and after middle cerebral artery occlusion.

  2004cites this paper
• Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization.

  2003cites this paper
• Patient selection for carotid angioplasty and stenting.

  2002cites this paper
• Persistent Defect in Transmitter Release and Synapsin Phosphorylation in Cerebral Cortex After Transient Moderate Ischemic Injury

  2002cites this paper
• Cerebral Atherosclerosis and Coronary Calcification

  2002cites this paper
• Nitric oxide may contribute to the long-term impairment of synaptic transmission after transient ischemia.

  2002cites this paper
• Cellular and molecular pathways of ischemic neuronal death.

  2002cites this paper
• Cerebral atherosclerosis and coronary calcification.

  2002cites this paper
• Parallel morning and evening surge in stroke onset, blood pressure, and physical activity.

  2002cites this paper
• Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies

  2001cites this paper
• Light scattering and transmission electron microscopy studies reveal a mechanism for calcium/calmodulin‐dependent protein kinase II self‐association

  2001cites this paper
• Alteration of second messengers during acute cerebral ischemia - adenylate cyclase, cyclic AMP-dependent protein kinase, and cyclic AMP response element binding protein.

  2001cites this paper
• Interplay Between the Gamma Isoform of PKC and Calcineurin in Regulation of Vulnerability to Focal Cerebral Ischemia

  2000cites this paper
• Persistent CREB phosphorylation with protection of hippocampal CA1 pyramidal neurons following temporary occlusion of the middle cerebral artery in the rat.

  2000cites this paper
• Expression of the alpha and beta subunits of Ca2+/calmodulin kinase II in the cerebellum of jaundiced Gunn rats during development: a quantitative light microscopic analysis.

  2000cites this paper
• Brain‐derived neurotrophic factor prevents neuronal death and glial activation after global ischemia in the rat

  1999cites this paper
• Ischemic cell death in brain neurons.

  1999cites this paper
• Immunoblot Analyses of the Relative Contributions of Cysteine and Aspartic Proteases to Neurofilament Breakdown Products Following Experimental Brain Injury in Rats

  1998cites this paper
• Microsphere embolism-induced changes in noradrenaline release in the cerebral cortex in rats.

  1998cites this paper
• Microsphere embolism-induced changes in noradrenaline uptake of the cerebral cortex in rats.

  1998cites this paper
• Changes in GABAA̳ Receptor Expression and Alterations in Ca⁺⁺/Calmodulin-Dependent Protein Kinase II Activity in a Hippocampal Neuronal Culture Model of Epilepsy

  1998cites this paper
• Intraoperative Pharmacologic Brain Protection

  1997cites this paper
• Mechanisms of calpain proteolysis following traumatic brain injury: implications for pathology and therapy: implications for pathology and therapy: a review and update.

  1997cites this paper
• Reperfusion Injury: Demonstration of Brain Damage Produced by Reperfusion after Transient Focal Ischemia in Rats

  1997cites this paper
• Mechanisms of Calpain Proteolysis Following Traumatic Brain Injury: Implications for Pathology and Therapy: A Review and Update

  1997cites this paper
• Ca2+/calmodulin-dependent protein kinase II in postsynaptic densities after reversible cerebral ischemia in rats.

  1996cites this paper
• Ischemia-Induced Neuronal Damage: A Role for Calcium/Calmodulin-Dependent Protein Kinase II

  1996cites this paper
• Autophosphorylation as a possible mechanism of calcium/calmodulin-dependent protein kinase II inhibition during ischemia.

  1996cites this paper
• Specific Induction of Protein Kinase Cδ Subspecies after Transient Middle Cerebral Artery Occlusion in the Rat Brain: Inhibition by MK-801

  1996cites this paper
• Multifunctional calcium and calmodulin-dependent kinase II in neuronal function and disease.

  1995cites this paper
• A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death

  1995cites this paper
• Bilirubin Induces a Calcium-Dependent Inhibition of Multifunctional Ca2+/Calmodulin-Dependent Kinase II Activity in Vitro

  1995cites this paper