The leukocyte NADPH oxidase.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  The Israel Medical Association journal : IMAJ

• Publication date

  2002-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12489496
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Killing activity of neutrophils is mediated through activation of proteases by K+ flux

  2002cited by this paper
• The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate.

  2001cited by this paper
• Formation of Nitrating and Chlorinating Species by Reaction of Nitrite with Hypochlorous Acid

  1996cited by this paper
• The role of iron-sulfur clusters in in vivo hydroxyl radical production.

  1996cited by this paper
• Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase.

  1996cited by this paper
• The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase.

  1996cited by this paper
• Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly.

  1996cited by this paper
• Peroxynitrite reaction with carbon dioxide/bicarbonate: kinetics and influence on peroxynitrite-mediated oxidations.

  1996cited by this paper
• Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes. Potentiometric studies of a mutant form of gp91phox.

  1995cited by this paper
• Structure of the green heme in myeloperoxidase.

  1995cited by this paper
• Regulation of the human neutrophil NADPH oxidase by the Rac GTP-binding proteins.

  1994cited by this paper
• Human neutrophil granules and secretory vesicles

  1993cited by this paper
• Cytotoxic activity and production of toxic nitrogen oxides by macrophages treated with IFN-gamma and monoclonal antibodies against the 73-kDa lipopolysaccharide receptor.

  1992cited by this paper
• Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

  1991cited by this paper
• Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

  1990cited by this paper
• NADPH:O2 oxidoreductase of human eosinophils in the cell‐free system

  1990cited by this paper
• Cloning of a 67-kD neutrophil oxidase factor with similarity to a noncatalytic region of p60c-src.

  1990cited by this paper
• Eosinophils preferentially use bromide to generate halogenating agents.

  1989cited by this paper
• Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase.

  1989cited by this paper
• The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex

  1987cited by this paper
• The association of FAD with the cytochrome b-245 of human neutrophils.

  1982cited by this paper
• Hydroxyl radical generation by polymorphonuclear leukocytes measured by electron spin resonance spectroscopy.

  1979cited by this paper
• Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent.

  1973cited by this paper
• Singlet oxygen: a unique microbicidal agent in cells.

  1973cited by this paper
• Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein).

  1969cited by this paper

• Modulation of the Functional State of Mouse Neutrophils by Selenium Nanoparticles In Vivo

  2022cites this paper
• Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells

  2020cites this paper
• Passion fruit (Passiflora edulis) leaf extract modulates the oxidative metabolism of rat peritoneal neutrophils in a model of inflammation

  2020cites this paper
• Small-size silver nanoparticles stimulate neutrophil oxidative burst through an increase of intracellular calcium levels

  2020cites this paper
• Transketolase and vitamin B1 influence on ROS-dependent neutrophil extracellular traps (NETs) formation

  2019cites this paper
• EFFECTS OF PHENOLIC COMPOUNDS EXTRACTED FROM SALVIA FRIGIDA ON INDUCED HYPERURICEMIA IN MICE

  2019cites this paper
• Natriuretic peptide receptor-C activation regulates vascular smooth muscle cell hypertrophy : molecular mechanisms

  2017cites this paper
• Principles of Redox Signaling

  2015cites this paper
• Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia

  2015cites this paper
• Identification de nouveaux facteurs de régulation physiopathologique de la NADPH oxydase du neutrophile : Importance de mTOR, de la dégradation de NOX2 via l’élastase et perspectives de traitement des déficits induits au cours de la cirrhose alcoolique

  2015cites this paper
• Effects of hyperbaric oxygen on Pseudomonas aeruginosa susceptibility to imipenem and macrophages.

  2015cites this paper
• Ethanolic extract of Passiflora edulis Sims leaves inhibits protein glycation and restores the oxidative burst in diabetic rat macrophages after Candida albicans exposure

  2015cites this paper
• Charakterisierung der Funktion des switch-associated protein 70 (SWAP-70) in der N-Formylpeptid-vermittelten Signaltransduktion muriner neutrophiler Granulozyten

  2015cites this paper
• Effect of silver nanoparticles on mitogen-activated protein kinases activation: role of reactive oxygen species and implication in DNA damage.

  2015cites this paper
• Cellular and Molecular Mechanisms of O2 Sensing

  2014cites this paper
• Dual Oxidase 2 in Lung Epithelia Is Essential for Hyperoxia-Induced Acute Lung Injury in Mice

  2014cites this paper
• Redox Circuitries Driving Src Regulation

  2014influential citation
• NAD(P)H oxidase isoforms as therapeutic targets for diabetic complications

  2014cites this paper
• Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways

  2014cites this paper
• Peroxynitrite as a Cytotoxic Effector Against Trypanosoma Cruzi: Oxidative Killing and Antioxidant Resistance Mechanisms

  2013cites this paper
• Oxidative Stress and an Alternative Glutathione-dependent Mechanism in the Developmental Toxicity of Methanol

  2013cites this paper
• JPET #201079 1 A novel non-toxic inhibitor of the activation of NADPH oxidase (NOX2) reduces reactive oxygen species production in mouse lung

  2013cites this paper
• Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion

  2013cites this paper
• Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury

  2013cites this paper
• Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity.

  2013cites this paper
• ROS-major mediators of extracellular matrix remodeling during tumor progression.

  2013cites this paper
• A Novel Nontoxic Inhibitor of the Activation of NADPH Oxidase Reduces Reactive Oxygen Species Production in Mouse Lung

  2013cites this paper
• In vitro drug metabolism testing using blood-monocyte derivatives

  2013cites this paper
• Inhibition of lysozyme by taurine dibromamine.

  2013cites this paper
• HOW ANTIOXIDANT AND ANTIOXIDANT ENZYME FUNCTIONS DO SUPPRESSED IN THE BRAIN TISSUES OF DEVELOPING CHICK EMBRYO UNDER THE INFLUENCE OF ACRYLAMIDE

  2013cites this paper
• Subversion of Host Recognition and Defense Systems by Francisella spp

  2012cites this paper
• Neutrophil dysfunction induced by hyperglycemia: modulation of myeloperoxidase activity

  2012cites this paper
• Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice

  2012cites this paper
• NADPH oxidase is involved in H2O2‐induced differentiation of human promyelocytic leukaemia HL‐60 cells

  2012cites this paper
• Acute and chronic atrial remodeling in obstructive sleep apnoea : implications for atrial fibrillation.

  2012cites this paper
• The role and regulatory mechanisms of nox1 in vascular systems

  2012cites this paper
• Interacciones entre el Escuticociliado parásito "Philasterides dicentrarchi" (Ciliophora: Scuticociliatia) y el sistema inmunitario del rodaballo, "Psetta maxima" (L.)

  2011cites this paper
• Protein disulfide isomerase redox‐dependent association with p47phox: evidence for an organizer role in leukocyte NADPH oxidase activation

  2011influential citation
• Cytokine and ROS Production by White Blood Cells after Exposure to Environmental Toxicants, Bacterial Analogs and Mixtures of These

  2011cites this paper
• Mecanismos de ação do palmitato como modulador da NADPH oxidase em ilhotas pancreáticas e linhagem INS-1 E.

  2011cites this paper
• NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction.

  2011cites this paper
• A INFLUÊNCIA DA PINEALECTOMIA NA FUNCIONALIDADE DAS CÉLULAS BETA PANCREÁTICAS

  2011cites this paper
• A INFLUÊNCIA DA PINEALECTOMIA NA FUNCIONALIDADE DAS CÉLULAS BETA PANCREÁTICAS

  2011cites this paper
• NADPH Oxidase in Human Phagocytes Acid Phosphatases Inactivate the Francisella

  2010cites this paper
• Compartmentalization of the redox environment in PC-12 neuronal cells

  2010cites this paper
• Evaluation of Vashe Wound Therapy in the Clinical Management of Patients with Chronic Wounds

  2010cites this paper
• Francisella Acid Phosphatases Inactivate the NADPH Oxidase in Human Phagocytes

  2010cites this paper
• The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos.

  2010cites this paper
• NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice.

  2009cites this paper
• Homocysteine and inflammation as main determinants of oxidative stress in the elderly.

  2009cites this paper
• Reactive species and diabetes: counteracting oxidative stress to improve health.

  2009cites this paper
• Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress link

  2009cites this paper
• NADPH oxidase expression and production of superoxide by human corneal stromal cells

  2009cites this paper
• Characterization of the ROS Production in Ischemia / Reperfusion-induced Lung Injury

  2009cites this paper
• Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells

  2009cites this paper
• Modèles murins déficients en NOX1 ou NOX2 : applications physiopathologiques

  2009cites this paper
• Optical probes for detection and quantification of neutrophils' oxidative burst. A review.

  2009cites this paper
• An investigation of NADPH oxidase in normal and diseased skeletal muscle

  2009influential citation
• ecanismo da interação entre a proteína dissulfeto isomerase e a NADPH oxidase : papel regulatório sobre a produção de espécies reativas de oxigênio em fagócitos profissionais

  2009cites this paper
• Characterization of the ROS Production in Ischemia/Reperfusion-induced Lung Injury

  2009cites this paper
• NOX1 plays a crucial role in hyperoxia-induced acute lung injury in mice

  2009cites this paper
• Rôles des NADPH oxydases lors de pathologies humaines à l'aide de modèles murins transgéniques

  2009cites this paper
• ENDOTHELINS AND NADPH OXIDASES IN THE CARDIOVASCULAR SYSTEM

  2008cites this paper
• Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis – there is nothing more practical than a good theory

  2008cites this paper
• Role of Glia in CNS Inflammation

  2008cites this paper
• Regulation of endothelial gene transcription by shear stress in a manner dependent on p47phox-based NADPH oxidases

  2008cites this paper
• Building and operating an antibody factory: redox control during B to plasma cell terminal differentiation.

  2008cites this paper
• Evolució molecular i estudi funcional de gens localitzats a les duplicacions segmentàries de la regió 7q11.23

  2006cites this paper
• Signaling through NADPH oxidases

  2006cites this paper
• Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures.

  2006cites this paper
• The Endoplasmic Reticulum: Folding, Calcium Homeostasis, Signaling, and Redox Control

  2006cites this paper
• Lipid Peroxidation and Activity of Some Antioxidant Enzymes in Patients with Glioblastoma and Astrocytoma

  2006cites this paper
• Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox.

  2006cites this paper
• Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.

  2005cites this paper
• Identification of MKP-1 as a central mediator of cytoprotective effects in human endothelial cells: pathways of induction

  2005cites this paper
• Antioxidant Vitamins Reduce Oxidative Stress and Ventricular Remodeling in Patients with Acute Myocardial Infarction

  2005cites this paper
• Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages.

  2004cites this paper
• Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

  2003cites this paper