Retinoic Acid and Polyriboinosinic:Polyribocytidylic Acid Stimulate Robust Anti-Tetanus Antibody Production while Differentially Regulating Type 1/Type 2 Cytokines and Lymphocyte Populations1

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Immunology

• Publication date

  2005-06-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.174.12.7961PMID 15944302PMCID PMC3843132
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications

  2012cited by this paper
• Vitamin A supplementation during pregnancy.

  2010cited by this paper
• Multiple sclerosis: interferon-beta induces CD123+BDCA2− dendritic cells that produce IL-6 and IL-10 and have no enhanced type I interferon production

  2005cited by this paper
• p38 MAPK activation controls the TLR3-mediated up-regulation of cytotoxicity and cytokine production in human NK cells.

  2004cited by this paper
• All-Trans Retinoic Acid and Interferon-α for Treatment of Human Renal Cell Carcinoma Multicellular Tumor Spheroids

  2004cited by this paper
• Physiological concentrations of retinoic acid favor myeloid dendritic cell development over granulocyte development in cultures of bone marrow cells from mice.

  2004cited by this paper
• IL-10 Released by Concomitant TLR2 Stimulation Blocks the Induction of a Subset of Th1 Cytokines That Are Specifically Induced by TLR4 or TLR3 in Human Dendritic Cells1

  2004cited by this paper
• Incremental cost-effectiveness of supplementary immunization activities to prevent neonatal tetanus in Pakistan.

  2004cited by this paper
• CpG-motifs enhance initial and sustained primary tetanus-specific antibody secreting cell responses in spleen and bone marrow, but are more effective in adult than in neonatal mice.

  2003cited by this paper
• Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors.

  2003cited by this paper
• Effect of vitamin A supplementation on measles-specific antibody levels in Guinea-Bissau.

  2002cited by this paper
• In Vivo CD86 Blockade Inhibits CD4+ T Cell Activation, Whereas CD80 Blockade Potentiates CD8+ T Cell Activation and CTL Effector Function1

  2002cited by this paper
• Adjuvant regulation of cytokine profile and antibody isotype of immune responses to Mycoplasma agalactiae in mice.

  2002cited by this paper
• Extent of vitamin A deficiency among preschool children and women of reproductive age.

  2002cited by this paper
• Retinoic acid enhances the T helper 2 cell development that is essential for robust antibody responses through its action on antigen-presenting cells.

  2002influential reference
• Opposing cytokine‐specific effects of all trans‐retinoic acid on the activation and expression of signal transducer and activator of transcription (STAT)‐1 in THP‐1 cells

  2002cited by this paper
• Decision making in the immune system: The lineage decisions of helper T cells

  2002cited by this paper
• All‐trans‐retinoic acid and polyriboinosinic : polyribocytidylic acid in combination potentiate specific antibody production and cell‐mediated immunity

  2001influential reference
• Vitamin A, infection, and immune function.

  2001cited by this paper
• What are the limits of adjuvanticity?

  2001cited by this paper
• Immunoprophylactic strategies against respiratory influenza virus infection.

  2001cited by this paper
• Interferon-beta induces the development of type 2 dendritic cells.

  2001cited by this paper
• Regulation of adaptive immune responses by innate cells expressing NK markers and antigen‐transporting macrophages

  2000cited by this paper
• Vitamin A and infectious diseases

  2000cited by this paper
• All-trans-retinoic acid and polyriboinosinoic : polyribocytidylic acid cooperate to elevate anti-tetanus immunoglobulin G and immunoglobulin M responses in vitamin A-deficient Lewis rats and Balb/c mice

  2000cited by this paper
• NKT cells: facts, functions and fallacies.

  2000cited by this paper
• Effect of vitamin A supplement on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: A randomized trial

  2000cited by this paper
• Retinoic acid and polyriboinosinic acid act synergistically to enhance the antibody response to tetanus toxoid during vitamin A deficiency: possible involvement of interleukin-2 receptor-beta, signal transducer and activator of transcription-1, and interferon regulatory factor-1.

  2000cited by this paper
• Vitamin A, retinoids and immune responses

  2000cited by this paper
• Polio as a platform: using national immunization days to deliver vitamin A supplements.

  2000cited by this paper
• Transcriptional regulation of Th1/Th2 polarization.

  2000cited by this paper
• Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells.

  1999influential reference
• Simultaneous vitamin A administration at routine immunization contact enhances antibody response to diphtheria vaccine in infants younger than six months.

  1999cited by this paper
• Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype.

  1999cited by this paper
• Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial.

  1999cited by this paper
• Retinoids Inhibit Interleukin-12 Production in Macrophages through Physical Associations of Retinoid X Receptor and NFκB*

  1999cited by this paper
• Cross-talk between retinoic acid and interferons: molecular mechanisms of interaction in acute promyelocytic leukemia cells.

  1998cited by this paper
• The role of vitamin A in reducing child mortality and morbidity and improving growth.

  1998cited by this paper
• Long-term treatment of malignant gliomas with intramuscularly administered polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethylcellulose: an open pilot study.

  1996cited by this paper
• Vitamin A down-regulation of IFN-gamma synthesis in cloned mouse Th1 lymphocytes depends on the CD28 costimulatory pathway.

  1996cited by this paper
• B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy.

  1995cited by this paper
• Polyinosinic acid: polycytidylic acid promotes T helper type 1‐specific immune responses by stimulating macrophage production of interferon‐α and interleukin‐12

  1995cited by this paper
• The effects of vitamin A supplementation on the morbidity of children born to HIV-infected women.

  1995cited by this paper
• Effect of vitamin A supplementation on diarrhoea and acute lower-respiratory-tract infections in young children in Brazil.

  1994cited by this paper
• Vitamin A supplementation during pregnancy

  1993cited by this paper
• Vitamin A status and immunoglobulin G subclasses in rats immunized with tetanus toxoid

  1993cited by this paper
• A randomized, controlled trial of vitamin A in children with severe measles.

  1990cited by this paper
• Production of interferon-alpha induced by dsRNA in human peripheral blood mononuclear cell cultures: role of priming by dsRNA-induced interferons-gamma and -beta.

  1989cited by this paper
• Production of Interferon-α Induced by dsRNA in Human Peripheral Blood Mononuclear Cell Cultures: Role of Priming by dsRNA-Induced Interferons-γ and -β

  1989cited by this paper
• Phase I-II trials of poly IC stabilized with poly-L-lysine.

  1978cited by this paper
• Phase I-II trials of poly IC stabilized with poly-L-lysine.

  1978cited by this paper

• Overview of Flow Injection, Chemiluminescence, and Spectrophotometric Methods for the Determination of Vitamin A

  2025cites this paper
• Association of fat-soluble vitamins (A, D, and E) status with humoral immune response to COVID-19 inactivated vaccination

  2023cites this paper
• Vitamin A and vitamin D induced nuclear hormone receptor activation and its impact on B cell differentiation and immunoglobulin production.

  2023cites this paper
• Assessment of cytochrome P450 1A1 gene polymorphism and vitamin A serum level in psoriasis vulgaris

  2023cites this paper
• Nano-Encapsulated Antioxidant: Retinoic Acid as a Natural Mucosal Adjuvant for Intranasal Immunization against Chronic Experimental Toxoplasmosis

  2023cites this paper
• An overview on role of nutrition on COVID-19 immunity: Accumulative review from available studies

  2022cites this paper
• All trans retinoic acid as a host-directed immunotherapy for tuberculosis

  2022cites this paper
• Vitamin A Plasma Levels in COVID-19 Patients: A Prospective Multicenter Study and Hypothesis

  2021cites this paper
• The role of vitamin A and vitamin D in modulation of the immune response with a focus on innate lymphoid cells

  2021cites this paper
• Regulation of the germinal center response by nuclear receptors and implications for autoimmune diseases

  2020cites this paper
• Mega doses of retinol: A possible immunomodulation in Covid‐19 illness in resource‐limited settings

  2020cites this paper
• Metabolism of Neonatal Vitamin A Supplementation: A Systematic Review

  2020cites this paper
• A Liposome-Based Adjuvant Containing Two Delivery Systems with the Ability to Induce Mucosal Immunoglobulin A Following a Parenteral Immunization.

  2019cites this paper
• The Role of the Status of Selected Micronutrients in Shaping the Immune Function

  2019cites this paper
• Impact of Retinoic Acid on Immune Cells and Inflammatory Diseases

  2018cites this paper
• Inducción Secretoria de IgG, con toxina de Clostridium perfringens Tipo A para la reducción de mortalidad por enterotoxemia en crías de Alpacas

  2018cites this paper
• Retinoic Acid, Leaky Gut, and Autoimmune Diseases

  2018cites this paper
• Single High-Dose Vitamin A Supplementation to Neonatal Piglets Results in a Transient Dose Response in Extrahepatic Organs and Sustained Increases in Liver Stores.

  2017cites this paper
• Molecular mechanisms of reversing neural degeneration by retinoic acid, a major derivative of vitamin A

  2017cites this paper
• Impact of Childhood Malnutrition on Host Defense and Infection

  2017cites this paper
• Retinyl Palmitate Supplementation Modulates T-bet and Interferon Gamma Gene Expression in Multiple Sclerosis Patients

  2016cites this paper
• Essential vitamins for an effective T cell response

  2016cites this paper
• All-trans-retinoic acid and CD38 ligation differentially regulate CD1d expression and α-galactosylceramide-induced immune responses.

  2015cites this paper
• Effect of Retinoic Acid in a Mouse Model of Allergic Rhinitis

  2015cites this paper
• Vitamin A-Deficient Hosts Become Nonsymptomatic Reservoirs of Escherichia coli-Like Enteric Infections

  2015cites this paper
• Leukocyte homing, fate, and function are controlled by retinoic acid.

  2015cites this paper
• Lactosucrose attenuates intestinal inflammation by promoting Th2 cytokine production and enhancing CD86 expression in colitic rats

  2015cites this paper
• α‐Galactosylceramide stimulates splenic lymphocyte proliferation in vitro and increases antibody production in vivo in late neonatal‐age mice

  2015cites this paper
• Vitamin A Deficiency Impairs Induction of Oral Tolerance in Mice.

  2015cites this paper
• Prepartum vitamin A supplementation enhances goat doe health status and kid viability and performance

  2015cites this paper
• Retinoic acid and iron metabolism: a step towards design of a novel antitubercular drug.

  2014cites this paper
• Enhancement of recombinant adenovirus vaccine-induced primary but not secondary systemic and mucosal immune responses by all-trans retinoic acid.

  2014cites this paper
• Adjuvanted poly(lactic-co-glycolic) acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs

  2014cites this paper
• Vitamin Deficiency and Tuberculosis: Need for Urgent Clinical Trial for Managment of Tuberculosis

  2014cites this paper
• Retinoid Signaling in Cancer and its Promise for Therapy

  2013cites this paper
• Effects of dietary vitamin A content on antibody responses of feedlot calves inoculated intramuscularly with an inactivated bovine coronavirus vaccine.

  2013cites this paper
• Feeding the immune system

  2013cites this paper
• Vitamin A Deficiency Impairs Adaptive B and T Cell Responses to a Prototype Monovalent Attenuated Human Rotavirus Vaccine and Virulent Human Rotavirus Challenge in a Gnotobiotic Piglet Model

  2013cites this paper
• Retinoic acid and α-galactosylceramide regulate the expression of costimulatory receptors and transcription factors responsible for B cell activation and differentiation.

  2013cites this paper
• Vitamin A and the immune system

  2013cites this paper
• Magíster en Ciencias Veterinarias con Mención en Salud Animal

  2013cites this paper
• 1 Vitamin A: Nutritional Aspects of Retinoids and Carotenoids

  2013cites this paper
• Retinoic acid alleviates Con A‐induced hepatitis and differentially regulates effector production in NKT cells

  2012cites this paper
• Immunization and vitamin A status as factors modulating an invasive Streptococcus pneumoniae-induced lung and a non-invasive Citrobacter rodentium gut infection in mice

  2012cites this paper
• Vitamin A and retinoic acid in T cell-related immunity.

  2012cites this paper
• Oral vitamin A and retinoic acid supplementation stimulates antibody production and splenic Stra6 expression in tetanus toxoid-immunized mice.

  2012cites this paper
• All-trans-retinoic acid and Erk1/2 signaling synergistically regulate the expression of CD300B in human monocytic cells.

  2011cites this paper
• The Fox and the Rabbits—Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease

  2011cites this paper
• Vitamin A and retinoic acid in the regulation of B-cell development and antibody production.

  2011influential citation
• Retinoic Acid and α-Galactosylceramide Differentially Regulate B Cell Activation In Vitro and Augment Antibody Production In Vivo

  2011cites this paper
• Neutrophils are immune cells preferentially targeted by retinoic acid in elderly subjects

  2010cites this paper
• Assessing the immunopotency of Toll‐like receptor agonists in an in vitro tissue‐engineered immunological model

  2010cites this paper
• Augmentation of antibody responses by retinoic acid and costimulatory molecules.

  2009cites this paper
• Relationship between immune function and serum vitamin A in Japanese black beef cattle.

  2009cites this paper
• Toll-Like Receptor 3 Ligand and Retinoic Acid Enhance Germinal Center Formation and Increase the Tetanus Toxoid Vaccine Response

  2009cites this paper
• In vitro effect of vitamin E on lectin-stimulated porcine peripheral blood mononuclear cells.

  2009cites this paper
• Localized Th1-, Th2-, T Regulatory Cell-, and Inflammation-Associated Hepatic and Pulmonary Immune Responses in Ascaris suum-Infected Swine Are Increased by Retinoic Acid

  2009cites this paper
• All‐trans retinoic acid potentiates the antibody response in mice to a lipopeptide antigen adjuvanted with liposomal lipid A

  2009cites this paper
• The maturation of the fetal and neonatal immune system.

  2008cites this paper
• Effect of exogenous vitamin E on proliferation and cytokine production in peripheral blood mononuclear cells from patients with tuberculosis

  2008cites this paper
• Vitamin A supplementation and retinoic acid treatment in the regulation of antibody responses in vivo.

  2007cites this paper
• Neonatal-age treatment with vitamin A delays postweaning vitamin A deficiency and increases the antibody response to T-cell dependent antigens in young adult rats fed a vitamin A-deficient diet.

  2007cites this paper
• Effects of dietary retinoids and carotenoids on immune development*

  2007cites this paper
• Retinoic Acid Regulates CD1d Gene Expression at the Transcriptional Level in Human and Rodent Monocytic Cells

  2007cites this paper
• Retinoic acid promotes mouse splenic B cell surface IgG expression and maturation stimulated by CD40 and IL-4.

  2007cites this paper
• Chronic vitamin A status and acute repletion with retinyl palmitate are determinants of the distribution and catabolism of all-trans-retinoic acid in rats.

  2007cites this paper
• Retinoic acid therapy attenuates the severity of tuberculosis while altering lymphocyte and macrophage numbers and cytokine expression in rats infected with Mycobacterium tuberculosis.

  2007cites this paper
• Analysis of immune response in young and aged mice vaccinated with corn-derived antigen against Escherichia coli heat-labile enterotoxin

  2006cites this paper
• Interactions of malnutrition and immune impairment, with specific reference to immunity against parasites

  2006cites this paper
• [Role and mechanism of action of vitamin A in gut immunity].

  2006cites this paper
• All-trans-retinoic acid distribution and metabolism in vitamin A-marginal rats.

  2006cites this paper
• Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells.

  2005cites this paper
• ALL-TRANS RETINOIC ACID COMBINED WITH POLYRIBOINOSINIC:POLYRIBOCYTIDYLIC ACID PROMOTES TETANUS TOXOID-INDUCED VACCINE RESPONSES IN ADULT AND NEONATAL MICE

  2005cites this paper
• The anti-tetanus immune response of neonatal mice is augmented by retinoic acid combined with polyriboinosinic:polyribocytidylic acid.

  2005cites this paper
• Profile of A. Catharine Ross.

  2005cites this paper