Glutathione contents in human and rodent tumor cells in various phases of the cell cycle.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Cancer Research

• Publication date

  1988-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 3378209
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Transplantable Human Neoplasms Maintained in Cortisonetreated Laboratory Animals: H.S.

  2006cited by this paper
• Comparison of glutathione levels in rodent and human tumor cells grown in vitro and in vivo.

  1988cited by this paper
• Glutathione as a determinant of cellular response to doxorubicin.

  1988cited by this paper
• Endogenous thiol levels in heterogeneous murine tumor cells as a function of the physiological state and the response to X‐irradiation

  1987cited by this paper
• Characterization of radiation resistant hypoxic cell subpopulations in KHT sarcomas. (I). Centrifugal elutriation.

  1987cited by this paper
• Depletion of tumour versus normal tissue glutathione by buthionine sulfoximine.

  1987cited by this paper
• Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent buthionine sulfoximine.

  1987cited by this paper
• Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.

  1987cited by this paper
• Elevation of intracellular glutathione content associated with mitogenic stimulation of quiescent fibroblasts

  1986influential reference
• Glutathione status during the mitogenic response of rat splenocytes. Effects of oxygen concentration: FO2 21% versus FO2 7%.

  1986cited by this paper
• Recovery of cell subpopulations from human tumour xenografts following dissociation with different enzymes.

  1986cited by this paper
• Cell cycle-dependent cytotoxicity of alkylating agents: determination of nitrogen mustard-induced DNA cross-links and their repair in Chinese hamster ovary cells synchronized by centrifugal elutriation.

  1986cited by this paper
• Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

  1985cited by this paper
• Potentiation and protection of doxorubicin cytotoxicity by cellular glutathione modulation.

  1985cited by this paper
• Comparison of tumour age response to radiation for cells derived from tissue culture or solid tumours.

  1984influential reference
• Cell cycle effects of alkylating agents.

  1984cited by this paper
• Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.

  1984cited by this paper
• Glutathione metabolism as a determinant of therapeutic efficacy: a review.

  1984cited by this paper
• Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II.

  1984cited by this paper
• Effects of culture conditions on glutathione content in A549 cells.

  1983cited by this paper
• The role of thiols in cellular response to radiation and drugs.

  1983cited by this paper
• Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis.

  1982cited by this paper
• Reduction in glutathione content of L-PAM resistant L1210 Cells confers drug sensitivity.

  1982cited by this paper
• Induction and repair of single-strand DNA breaks after X-irradiation of human fibroblasts deficient in glutathione.

  1981cited by this paper
• Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation.

  1981cited by this paper
• An experimental and analytical study of oxygen depletion in stirred cell suspensions.

  1980influential reference
• Age-dependent survival and cell-cycle progression of cultured cells exposed to chemotherapeutic drugs.

  1976cited by this paper
• Effect of adriamycin on the cell cycle traverse and kinetics of cultured human lymphoblasts.

  1976cited by this paper
• Variations of cellular sulfhydryl content during cell cycle of HeLa cells and its correlation to cyclic change of x-ray sensitivity.

  1969cited by this paper
• Factors influencing the quantitative estimation of the in vivo survival of cells from solid tumors.

  1967cited by this paper
• X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells.

  1966cited by this paper
• Transplantable human neoplasms maintained in cortisone-treated laboratory animals: H.S. No. 1; H.Ep. No. 1; H.Ep. No. 2; H.Ep. No. 3; and H.Emb.Rh. No. 1.

  1954cited by this paper

• The role of the glutathione system in regulating the levels of ROSneutralisation in the endothelial cells of the blood-brain barrier

  2017cites this paper
• Tratamiento del cáncer colorrectal desde una perspectiva cronofarmacológica

  2016cites this paper
• Regulation of glutathione synthesis.

  2009cites this paper
• [Determinants and predictive factors of tumour radiosensitivity].

  2008cites this paper
• Identification of amide protons of glutathione in MR spectra of tumour cells

  2008cites this paper
• Free radical equilibrium in interscapular brown adipose tissue: relationship between metabolic profile and antioxidative defense.

  2006cites this paper
• Novobiocin , an Inhibitor of Mammalian Topoisomerase II Adriamycin and 4-Hydroperoxycyclophosphamide by Modulation of the Cell Cycle-dependent Cytotoxicity of Updated Version

  2006cites this paper
• Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals.

  2006cites this paper
• Noninvasive monitoring of glutathione turnover in perfused MCF-7 cells.

  2004cites this paper
• Rhythms in human bone marrow and blood cells

  2002cites this paper
• Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy.

  2002cites this paper
• Radiatio nEffect so nSolubl eMetabolite sin Culture dHeL aCell sExamine dby 1 HMRS: Change si nConcentratio no fGlutathion ean do fLipid Catabolite sInduce db yGamm aRay san dProto nBeams

  2001cites this paper
• Radiation effects on soluble metabolites in cultured HeLa cells examined by 1H MRS: Changes in concentration of glutathione and of lipid catabolites induced by gamma rays and proton beams

  2001cites this paper
• Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration

  2001cites this paper
• Regulation of glutathione synthesis.

  2000cites this paper
• Part VII • Chapter 17 – Oxidative stress indices: analytical aspects and significance

  2000cites this paper
• Oxidative stress and gene regulation.

  2000cites this paper
• Elevation of glutathione level in rat hepatocytes by hepatocyte growth factor via induction of gamma-glutamylcysteine synthetase.

  1999cites this paper
• Regulation of hepatic glutathione synthesis: current concepts and controversies

  1999cites this paper
• Gamma-glutamylcysteine synthetase activity in human lung epithelial (A549) cells: factors influencing its measurement.

  1999cites this paper
• Regulation of Hepatic Glutathione Synthesis

  1998cites this paper
• Changes in glutathione homeostasis during liver regeneration in the rat

  1998cites this paper
• Modulation of antioxidant enzymes, reactive oxygen species, and glutathione levels in manganese superoxide dismutase‐overexpressing NIH/3T3 fibroblasts during the cell cycle

  1998cites this paper
• Redox state changes in density-dependent regulation of proliferation.

  1997cites this paper
• Glutathione content of V79 cells in two- or three-dimensional culture.

  1997cites this paper
• Effect of Buthionine Sulfoximine, a Synthesis Inhibitor of the Antioxidant Glutathione, on the Murine Nigrostriatal Neurons

  1996cites this paper
• Biologic rhythms in hematology.

  1996cites this paper
• Kinetic factors that control the fate of thiyl radicals in cells.

  1995cites this paper
• Modifications of cellular thiols during growth and squamous differentiation of cultured human bronchial epithelial cells.

  1994cites this paper
• In vivo therapeutic potential of combination thiol depletion and alkylating chemotherapy.

  1993cites this paper
• Depletion of tumour glutathione in vivo by buthionine sulphoximine: modulation by the rate of cellular proliferation and inhibition of cancer growth.

  1993cites this paper
• Modulation of human microvascular endothelial cell bioenergetic status and glutathione levels during proliferative and differentiated growth

  1993cites this paper
• Taxol in combination with doxorubicin or etoposide possible antagonism in vitro

  1993cites this paper
• Modulation of Glutathione Level in CHO Cells

  1992cites this paper
• [The antioxidant properties of tumor cell subpopulations].

  1992cites this paper
• Modulation of the cell cycle-dependent cytotoxicity of adriamycin and 4-hydroperoxycyclophosphamide by novobiocin, an inhibitor of mammalian topoisomerase II.

  1992cites this paper
• Chronobiology of Human Bone Marrow

  1992cites this paper
• CHO cell responses to low oxygen: Regulation of oxygen consumption and sensitization to oxidative stress

  1992cites this paper
• Loss of suppression of GSH synthesis at low cell density in primary cultures of rat hepatocytes.

  1992cites this paper
• Influence of glutathione S-transferases on cellular glutathione determination by flow cytometry using monochlorobimane.

  1991cites this paper
• Glutathione content in human bone marrow and circadian stage relation to DNA synthesis.

  1991cites this paper
• Interleukin 1 alpha stimulates hemopoiesis but not tumor cell proliferation and protects mice from lethal total body irradiation.

  1991cites this paper
• Increased glutathione levels in quiescent, serum‐stimulated NRK‐49F cells are associated not with a response to growth factors but with nutrient repletion

  1991cites this paper
• The sensitivities of SV40-transformed human fibroblasts to monofunctional and DNA-crosslinking alkylating agents.

  1991cites this paper
• Prediction of tumour sensitivity to 4-hydroperoxycyclophosphamide by a glutathione-targeted assay.

  1991cites this paper
• In vivo and in vitro mechanisms of drug resistance in a rat mammary carcinoma model.

  1991cites this paper
• Increased sensitivity to cis-diamminedichloroplatinum(II) in human ovarian carcinoma cells in response to treatment with 12-O-tetradecanoylphorbol 13-acetate.

  1990cites this paper
• Comparison between in vitro radiosensitivity and in vivo radioresponse of murine tumor cell lines. I: Parameters of in vitro radiosensitivity and endogenous cellular glutathione levels.

  1990cites this paper
• Blood levels of reduced and oxidized glutathione in malignant and non-malignant human colorectal lesions.

  1990cites this paper
• Growth‐associated modifications of low‐molecular‐weight thiols and protein sulfhydryls in human bronchial fibroblasts

  1990cites this paper
• Cadmium cytotoxicity correlates with the changes in glutathione content that occur during the logarithmic growth phase of A549-T27 cells.

  1990cites this paper
• Influence of cell cycle on glutathione-S-transferase, selenium-dependent glutathione peroxidase, superoxide dismutase and glutathione levels in human myeloid leukaemia cell lines.

  1989cites this paper
• Isolation by flow cytometry of a human ovarian tumor cell subpopulation exhibiting a high glutathione content phenotype and increased resistance to adriamycin.

  1989cites this paper
• The role of glutathione in cadmium cytotoxic response in human lung carcinoma A549 cells

  1989cites this paper
• A study of the mechanism of resistance to Adriamycin in vivo. Glutathione metabolism, P-glycoprotein expression, and drug transport.

  1989cites this paper
• Comparison of glutathione levels in rodent and human tumor cells grown in vitro and in vivo.

  1988cites this paper
• Mechanism and Significance of Increased Glutathione Level in Human Hepatocellular Carcinoma and Liver Regeneration Western Blot Analysis of Gcs-hs Nuclear Run-on Transcription Assay Electrophoretic Mobility Shift Assay (emsa)

  year unknowncites this paper