Quantitative contributions of CtBP-dependent and -independent repression activities of Knirps

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Development

• Publication date

  2004-05-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/dev.01075PMID 15128671
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CtBP Contributes Quantitatively to Knirps Repression Activity in an NAD Binding-Dependent Manner

  2004cited by this paper
• CtBP-Independent Repression in the Drosophila Embryo

  2003cited by this paper
• A self-organizing system of repressor gradients establishes segmental complexity in Drosophila

  2003cited by this paper
• Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities.

  2003cited by this paper
• Nicotinamide adenine dinucleotide stimulates oligomerization, interaction with adenovirus E1A and an intrinsic dehydrogenase activity of CtBP

  2003cited by this paper
• Coordinated histone modifications mediated by a CtBP co-repressor complex

  2003cited by this paper
• Information display by transcriptional enhancers

  2003cited by this paper
• Extraction of functional binding sites from unique regulatory regions: the Drosophila early developmental enhancers.

  2002cited by this paper
• Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes

  2002cited by this paper
• Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome

  2002influential reference
• CtBP, an unconventional transcriptional corepressor in development and oncogenesis.

  2002influential reference
• Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase.

  2002cited by this paper
• The repressor activity of Even-skipped is highly conserved, and is sufficient to activate engrailed and to regulate both the spacing and stability of parasegment boundaries.

  2002cited by this paper
• Role of CtBP in transcriptional repression by the Drosophila giant protein.

  2001cited by this paper
• Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries.

  2001cited by this paper
• Transcriptional regulation of the Drosophila gene zen by competing Smad and Brinker inputs.

  2001cited by this paper
• The CtBP family: enigmatic and enzymatic transcriptional co‐repressors

  2001cited by this paper
• Brinker requires two corepressors for maximal and versatile repression in Dpp signalling

  2001cited by this paper
• Brinker is a sequence-specific transcriptional repressor in the Drosophila embryo.

  2001cited by this paper
• dCtBP-Dependent and -Independent Repression Activities of the Drosophila Knirps Protein

  2000cited by this paper
• Evidence for stabilizing selection in a eukaryotic enhancer element

  2000influential reference
• Using Antibodies: A Laboratory Manual

  1999cited by this paper
• Transcriptional repression by the Drosophila giant protein: cis element positioning provides an alternative means of interpreting an effector gradient.

  1999cited by this paper
• Independent Repressor Domains in ZEB Regulate Muscle and T-Cell Differentiation

  1999cited by this paper
• hairy stripe 7 element mediates activation and repression in response to different domains and levels of Krüppel in the Drosophila embryo.

  1999cited by this paper
• Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients.

  1999influential reference
• Groucho and dCtBP mediate separate pathways of transcriptional repression in the Drosophila embryo.

  1999cited by this paper
• Drosophila CtBP: a Hairy‐interacting protein required for embryonic segmentation and Hairy‐mediated transcriptional repression

  1998cited by this paper
• dCtBP mediates transcriptional repression by Knirps, Krüppel and Snail in the Drosophila embryo

  1998cited by this paper
• Activation of posterior pair-rule stripe expression in response to maternal caudal and zygotic knirps activities.

  1998influential reference
• Interaction of short-range repressors with Drosophila CtBP in the embryo.

  1998influential reference
• Functional analysis of eve stripe 2 enhancer evolution in Drosophila: rules governing conservation and change.

  1998cited by this paper
• Concentration-dependent patterning by an ectopic expression domain of the Drosophila gap gene knirps.

  1997influential reference
• Groucho-dependent and -independent repression activities of Runt domain proteins

  1997cited by this paper
• In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters.

  1996cited by this paper
• Short-range transcriptional repressors mediate both quenching and direct repression within complex loci in Drosophila.

  1996cited by this paper
• Transcriptional repression in development.

  1996cited by this paper
• Regulation of two pair-rule stripes by a single enhancer in the Drosophila embryo.

  1996cited by this paper
• The gap protein knirps mediates both quenching and direct repression in the Drosophila embryo.

  1996cited by this paper
• Multiple modes of dorsal‐bHLH transcriptional synergy in the Drosophila embryo.

  1995cited by this paper
• Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.

  1995cited by this paper
• Non-periodic cues generate seven ftz stripes in the Drosophila embryo.

  1995influential reference
• Positioning adjacent pair-rule stripes in the posterior Drosophila embryo.

  1994influential reference
• Functional and conserved domains of the Drosophila transcription factor encoded by the segmentation gene knirps

  1994cited by this paper
• Regulation of runt transcription by Drosophila segmentation genes.

  1993cited by this paper
• Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen.

  1993cited by this paper
• Regulation of even‐skipped stripe 2 in the Drosophila embryo.

  1992cited by this paper
• Competition for overlapping sites in the regulatory region of the Drosophila gene Krüppel.

  1992cited by this paper
• Concentration-dependent activities of the even-skipped protein in Drosophila embryos.

  1992cited by this paper
• Individual stripe regulatory elements in the Drosophila hairy promoter respond to maternal, gap, and pair-rule genes.

  1991cited by this paper
• Eukaryotic start and stop translation sites.

  1991influential reference
• Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the Drosophila embryo.

  1990cited by this paper
• The gradient morphogen bicoid is a concentration-dependent transcriptional activator.

  1989cited by this paper
• Vectors for P-mediated transformation in Drosophila.

  1988cited by this paper
• Zygotically active genes that affect the spatial expression of the fushi tarazu segmentation gene during early Drosophila embryogenesis.

  1986cited by this paper

• Epigenetic inheritance and gene expression regulation in early Drosophila embryos

  2024cites this paper
• Deciphering enhancer sequence using thermodynamics-based models and convolutional neural networks

  2021cites this paper
• Quantitatively predictable control of Drosophila transcriptional enhancers in vivo with engineered transcription factors

  2016influential citation
• Genome-wide errant targeting by Hairy

  2015cites this paper
• Control of Drosophila embryo patterning by transcriptional co-regulators.

  2014cites this paper
• CtBP Family Proteins: Unique Transcriptional Regulators in the Nucleus with Diverse Cytosolic Functions

  2013cites this paper
• Unraveling Mechanisms of Transcriptional Repression: Novel Insights from Brinker

  2013cites this paper
• Brinker possesses multiple mechanisms for repression because its primary co-repressor, Groucho, may be unavailable in some cell types

  2013cites this paper
• The Tbx20 homolog Midline represses wingless in conjunction with Groucho during the maintenance of segment polarity.

  2012cites this paper
• Combinatorial activation and concentration-dependent repression of the Drosophila even skipped stripe 3+7 enhancer

  2011cites this paper
• The oligomeric state of CtBP determines its role as a transcriptional co‐activator and co‐repressor of Wingless targets

  2011cites this paper
• CtBP Family Proteins

  2011cites this paper
• Fine mapping of chromatin structure in Drosophila melanogaster embryos using micrococcal nuclease

  2010cites this paper
• The molecular genetics of congenital heart disease: a review of recent developments

  2010cites this paper
• Role of Protein Oligomerization in Regulation of Wnt Target Gene Transcription.

  2010cites this paper
• CtBP is required for proper development of peripheral nervous system in Drosophila.

  2009cites this paper
• Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor

  2009cites this paper
• SAP18 Promotes Krüppel-dependent Transcriptional Repression by Enhancer-specific Histone Deacetylation*

  2009cites this paper
• Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex.

  2008cites this paper
• A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm.

  2008cites this paper
• Drosophila Ebi mediates Snail‐dependent transcriptional repression through HDAC3‐induced histone deacetylation

  2008cites this paper
• Constructing a Quantitative Spatio-temporal Atlas of Gene Expression in the Drosophila Blastoderm

  2007cites this paper
• XSip1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms.

  2007cites this paper
• CtBP and Hematopoietic Transcriptional Regulators

  2007cites this paper
• Transcriptional Repression by the CtBP Corepressor in Drosophila

  2007cites this paper
• XSip 1 neuralizing activity involves the co-repressor CtBP and occurs through BMP dependent and independent mechanisms

  2007cites this paper
• The Tailless Nuclear Receptor Acts as a Dedicated Repressor in the Early Drosophila Embryo

  2006cites this paper
• Transcriptional Repressors and Repression Mechanisms

  2006cites this paper
• Functional Interaction between the Drosophila Knirps Short Range Transcriptional Repressor and RPD3 Histone Deacetylase*

  2005cites this paper
• cis-Regulatory Logic of Short-Range Transcriptional Repression in Drosophila melanogaster

  2005cites this paper
• Multiple Mechanisms of Transcriptional Repression in Eukaryotes

  2004influential citation
• CtBP Contributes Quantitatively to Knirps Repression Activity in an NAD Binding-Dependent Manner

  2004cites this paper
• Repression of Dpp targets in the Drosophila wing by Brinker

  2004cites this paper
• Repressors Induce Distinct Chromatin States on Repressed Genes

  year unknowninfluential citation