Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Nature Cell Biology

• Publication date

  2003-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/ncb941PMID 12598904
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Review: Amino acid domains involved in constitutive activation of G-protein-coupled receptors

  2007cited by this paper
• GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins.

  2000cited by this paper
• High constitutive activity of native H3 receptors regulates histamine neurons in brain

  2000cited by this paper
• Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1

  2000cited by this paper
• Destabilized green fluorescent protein for monitoring dynamic changes in yeast gene expression with flow cytometry

  2000cited by this paper
• Pheromone response, mating and cell biology.

  2000cited by this paper
• A Saccharomyces cerevisiae G‐protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose

  1999cited by this paper
• The expanding spectrum of G protein diseases.

  1999cited by this paper
• Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast.

  1998cited by this paper
• Selective Uncoupling of RGS Action by a Single Point Mutation in the G Protein α-Subunit*

  1998cited by this paper
• GAIP and RGS4 Are GTPase-Activating Proteins for the Gi Subfamily of G Protein α Subunits

  1996cited by this paper
• Defects in G protein-coupled signal transduction in human disease.

  1996cited by this paper
• GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits.

  1996cited by this paper
• Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

  1996cited by this paper
• EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins.

  1996cited by this paper
• Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit)

  1996cited by this paper
• Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae

  1995cited by this paper
• Heat-inducible degron: a method for constructing temperature-sensitive mutants.

  1994cited by this paper
• Cloning of the STE5 gene of Saccharomyces cerevisiae as a suppressor of the mating defect of cdc25 temperature-sensitive mutants.

  1993cited by this paper
• Cell-type-specific transcription in yeast.

  1991cited by this paper
• Purification and characterization of Go alpha and three types of Gi alpha after expression in Escherichia coli.

  1990cited by this paper
• G protein mutations that alter the pheromone response in Saccharomyces cerevisiae

  1990cited by this paper
• Expression of Gs alpha in Escherichia coli. Purification and properties of two forms of the protein.

  1989cited by this paper
• The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein.

  1989cited by this paper
• A mutation that prevents GTP-dependent activation of the alpha chain of Gs.

  1988cited by this paper
• A mutation that prevents GTP-dependent activation of the α chain of Gs

  1988cited by this paper
• Down regulation of the alpha-factor pheromone receptor in S. cerevisiae.

  1986cited by this paper
• Down regulation of the α-factor pheromone receptor in S. cerevisiae

  1986cited by this paper
• Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor.

  1984cited by this paper
• Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-α-factor

  1984cited by this paper
• Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones

  1982cited by this paper
• Physiological characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones

  1982cited by this paper
• Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone

  1980cited by this paper

• Haploinsufficiency of the sex-determining genes at MATα restricts genome expansion in Saccharomyces cerevisiae

  2022cites this paper
• How to Select a Mate: Kel1 is a Phosphorylation-Regulated Suppressor of the Pheromone Signaling Pathway

  2021cites this paper
• Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway

  2021cites this paper
• Negative feedback-loop mechanisms regulating HOG- and pheromone-MAPK signaling in yeast

  2020cites this paper
• Spontaneous Post-translational Modification Crosstalk of Proteolysis, Autophagy, and Apoptosis in Aging

  2020cites this paper
• Negative feedback-loop mechanisms regulating HOG- and pheromone-MAPK signaling in yeast

  2020cites this paper
• Quantitative analysis of the yeast pheromone pathway

  2019cites this paper
• Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity

  2019cites this paper
• Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control

  2018cites this paper
• Amino acid metabolites that regulate G protein signaling during osmotic stress

  2017cites this paper
• Coordination of G Protein and Mitogen-Activated Protein Kinase Signaling Pathways by Branched-Chain Amino Acid Metabolite Second Messengers during Osmotic Stress

  2017influential citation
• Heterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone Response

  2016cites this paper
• Variable Dependence of Signaling Output on Agonist Occupancy of Ste2p, a G Protein-coupled Receptor in Yeast*

  2016cites this paper
• Yeast GPCR signaling reflects the fraction of occupied receptors, not the number

  2016cites this paper
• photoreceptors Drosophila quantum bump amplification in Common mechanisms regulating dark noise and

  2015cites this paper
• Regulation of cell morphogenesis by targeted noise suppression and trafficking of a G protein alpha subunit

  2014cites this paper
• Cellular noise suppression by the regulator of G protein signaling Sst2.

  2014cites this paper
• Different exosome cargo from plasma/bronchoalveolar lavage in non‐small‐cell lung cancer

  2014cites this paper
• Specific α-Arrestins Negatively Regulate Saccharomyces cerevisiae Pheromone Response by Down-Modulating the G-Protein-Coupled Receptor Ste2

  2014cites this paper
• Common mechanisms regulating dark noise and quantum bump amplification in Drosophila photoreceptors.

  2013cites this paper
• Dynamically Reshaping Signaling Networks to Program Cell Fate via Genetic Controllers

  2013cites this paper
• Engineered quorum sensing using pheromone-mediated cell-to-cell communication in Saccharomyces cerevisiae.

  2013cites this paper
• Studies on mating in the budding yeast

  2013cites this paper
• A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity

  2012cites this paper
• Phospholipase C-Mediated Suppression of Dark Noise Enables Single-Photon Detection in Drosophila Photoreceptors

  2012cites this paper
• A framework for mapping, visualisation and automatic model creation of signal-transduction networks

  2012cites this paper
• Silencing of G proteins uncovers diversified plant responses when challenged by three elicitors in Nicotiana benthamiana.

  2012cites this paper
• High-Throughput Strategies for the Scalable Generation of RNA Component Functions

  2012influential citation
• Pheromone- and RSP5-dependent Ubiquitination of the G Protein β Subunit Ste4 in Yeast*

  2011cites this paper
• Synthetic Morphology Using Alternative Inputs

  2009cites this paper
• Characterization of coronin 2A and its role in regulating cofilin activity

  2009cites this paper
• Yeast-based fluorescence reporter assay of G protein-coupled receptor signalling for flow cytometric screening: FAR1-disruption recovers loss of episomal plasmid caused by signalling in yeast.

  2008cites this paper
• Protein kinase A-dependent phosphorylation and degradation of CDK8 : implications for yeast filamentous growth

  2008cites this paper
• RGS domain-independent Sst2 action

  2008cites this paper
• Over-expression of a truncated Arabidopsis thaliana heterotrimeric G protein gamma subunit results in a phenotype similar to alpha and beta subunit knockouts.

  2007cites this paper
• Over-expression of a truncated Arabidopsis thaliana heterotrimeric G protein γ subunit results in a phenotype similar to α and β subunit knockouts

  2007cites this paper
• Bistability, stochasticity, and oscillations in the mitogen-activated protein kinase cascade.

  2006cites this paper
• DEP-domain-mediated regulation of GPCR signaling responses.

  2006cites this paper
• Mathematical modeling of signaling pathway dynamics and stochastic gene expression

  2006cites this paper
• Investigating RGS proteins in yeast.

  2006cites this paper
• Genome-Scale Analysis Reveals Sst2 as the Principal Regulator of Mating Pheromone Signaling in the Yeast Saccharomyces cerevisiae

  2006influential citation
• Formin-induced actin cables are required for polarized recruitment of the Ste5 scaffold and high level activation of MAPK Fus3

  2005cites this paper
• Mitogen-Activated Protein Kinases with Distinct Requirements for Ste5 Scaffolding Influence Signaling Specificity in Saccharomyces cerevisiae

  2005cites this paper
• Functional analysis of heterologous GPCR signalling pathways in yeast.

  2005cites this paper
• Galpha protein dependent and independent effects of human RGS1 expression in yeast.

  2004cites this paper
• Female pig urethral tone is dependent on Rho guanosine triphosphatases and Rho-associated kinase.

  2004cites this paper
• Gα protein dependent and independent effects of human RGS1 expression in yeast

  2004cites this paper
• Cryptococcus neoformans Signaling Crg 1 Increases Virulence in Mutation of the Regulator of G Protein

  2004cites this paper
• Localized Feedback Phosphorylation of Ste5p Scaffold by Associated MAPK Cascade*

  2004cites this paper
• Mutation of the Regulator of G Protein Signaling Crg1 Increases Virulence in Cryptococcus neoformans

  2004cites this paper
• T Cell Receptor-Independent Basal Signaling via Erk and Abl Kinases Suppresses RAG Gene Expression

  2003cites this paper
• Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis

  2003cites this paper
• Short Article The Yeast G Protein Subunit Gpa1 Transmits a Signal through an RNA Binding Effector Protein Scp160

  2003cites this paper
• ArticleThe Yeast G Protein Subunit Gpa 1 Transmits a Signal through an RNA Binding Effector Protein Scp

  2003cites this paper
• Regulators of G Protein Signaling and Transient Activation of Signaling

  2003cites this paper
• Transactivation joins multiple tracks to the ERK/MAPK cascade

  2003cites this paper
• Recapitulation of the Sexual Cycle of the Primary Fungal Pathogen Cryptococcus neoformans var. gattii: Implications for an Outbreak on Vancouver Island, Canada

  2003cites this paper
• Dynamic Expression of RGS4 in the Developing Nervous System and Regulation by the Neural Type-Specific Transcription Factor Phox2b

  2003cites this paper
• The yeast G protein alpha subunit Gpa1 transmits a signal through an RNA binding effector protein Scp160.

  2003cites this paper