The dual role of fission yeast Tbc1/cofactor C orchestrates microtubule homeostasis in tubulin folding and acts as a GAP for GTPase Alp41/Arl2

Tbc1 is identified as the fission yeast orthologue of tubulin-folding cofactor C. In addition to its roles in tubulin folding, Tbc1 acts as a GAP in regulating the small GTPase Alp41/Arl2, which interacts with cofactor D Alp1. A model is given of the final stages of the tubulin cofactor pathway.

• Publication year

  2013

• Venue

  Molecular Biology of the Cell

• Publication date

  2013-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1091/mbc.E12-11-0792PMID 23576550PMCID 3667724
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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