Evidence that SP1 Modulates Transcriptional Activity of the Multidrug Resistance-Associated Protein Gene

No abstract is available for this paper.

• Publication year

  1996

• Venue

  DNA and Cell Biology

• Publication date

  1996-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/dna.1996.15.105PMID 8634138
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphorylation of the multidrug resistance associated protein gene encoded protein P190.

  1995cited by this paper
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  1995cited by this paper
• Possible involvement of multidrug‐resistance‐associated protein (MRP) gene expression in spontaneous drug resistance to vincristine, etoposide and adriamycin in human glioma cells

  1994cited by this paper
• ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

  1994cited by this paper
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  1994cited by this paper
• Expression of the multidrug resistance-associated protein (MRP) gene correlates with amplification and overexpression of the N-myc oncogene in childhood neuroblastoma.

  1994cited by this paper
• Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

  1994cited by this paper
• High expression of the multidrug resistance‐associated protein (MRP) in chronic and prolymphocytic leukaemia

  1994cited by this paper
• Cloning and sequence analysis of the promoter region of the MRP gene of HL60 cells isolated for resistance to adriamycin.

  1994cited by this paper
• Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

  1994cited by this paper
• Analysis of MRP gene expression and function in HL60 cells isolated for resistance to adriamycin.

  1994cited by this paper
• A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.

  1994cited by this paper
• Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene.

  1994cited by this paper
• Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines.

  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein.

  1993cited by this paper
• SP1 activates the MDR1 promoter through one of two distinct G-rich regions that modulate promoter activity.

  1993cited by this paper
• Three distinct nuclear protein binding sites in the promoter of the murine multidrug resistance mdr1b gene.

  1993cited by this paper
• Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines.

  1993cited by this paper
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  1993cited by this paper
• Characterization of the human ADP-ribosylation factor 3 promoter. Transcriptional regulation of a TATA-less promoter.

  1993cited by this paper
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  1992cited by this paper
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  1989influential reference
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  1986cited by this paper
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• Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

  1983cited by this paper
• DNA sequencing with chain-terminating inhibitors.

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  2003cites this paper
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  2003influential citation
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• Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution

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• Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site.

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• Hammerhead ribozyme against γ-glutamylcysteine synthetase sensitizes human colonic cancer cells to cisplatin by down-regulating both the glutathione synthesis and the expression of multidrug resistance proteins

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• Selection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness.

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  1998influential citation
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