Tbx5 Is Required for Avian and Mammalian Epicardial Formation and Coronary Vasculogenesis

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Circulation Research

• Publication date

  2014-10-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/CIRCRESAHA.115.304379PMID 25245104PMCID PMC4727243
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Epicardium and the Development of the Atrioventricular Junction in the Murine Heart

  2014cited by this paper
• Tbx18 regulates development of the epicardium and coronary vessels.

  2013cited by this paper
• Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries

  2013cited by this paper
• The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors

  2012cited by this paper
• Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart.

  2012cited by this paper
• Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation.

  2012cited by this paper
• Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells.

  2012cited by this paper
• Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.

  2012cited by this paper
• Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation

  2012cited by this paper
• Epithelial-to-Mesenchymal and Endothelial-to-Mesenchymal Transition: From Cardiovascular Development to Disease

  2012cited by this paper
• Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.

  2012cited by this paper
• Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart.

  2012cited by this paper
• Cardiac regeneration.

  2012cited by this paper
• MicroRNA-processing Enzyme Dicer Is Required in Epicardium for Coronary Vasculature Development*

  2011cited by this paper
• Hand2 Loss-of-Function in Hand1-Expressing Cells Reveals Distinct Roles in Epicardial and Coronary Vessel Development

  2011cited by this paper
• Holt–Oram syndrome: novel TBX5 mutation and associated anomalous right coronary artery

  2011influential reference
• Signaling During Epicardium and Coronary Vessel Development

  2011cited by this paper
• WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways.

  2011influential reference
• Differential Notch Signaling in the Epicardium Is Required for Cardiac Inflow Development and Coronary Vessel Morphogenesis

  2011cited by this paper
• An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation

  2010cited by this paper
• Epicardial-myocardial signaling directing coronary vasculogenesis.

  2010influential reference
• Wt1 and Retinoic Acid Signaling in the Subcoelomic Mesenchyme Control the Development of the Pleuropericardial Membranes and the Sinus Horns

  2010cited by this paper
• Coronary arteries form by developmental reprogramming of venous cells

  2010cited by this paper
• Epicardial spindle orientation controls cell entry into the myocardium.

  2010cited by this paper
• Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish

  2010influential reference
• Revealing global regulatory perturbations across human cancers.

  2009cited by this paper
• Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development

  2009cited by this paper
• Tbx18 and the fate of epicardial progenitors

  2009cited by this paper
• E-cadherin surface levels in epithelial growth factor-stimulated cells depend on adherens junction protein shrew-1.

  2009cited by this paper
• Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

  2009influential reference
• Non–Cell-Autonomous Roles for the Planar Cell Polarity Gene Vangl2 in Development of the Coronary Circulation

  2008cited by this paper
• Tbx5-dependent pathway regulating diastolic function in congenital heart disease

  2008cited by this paper
• Holt-Oram syndrome presenting as agenesis of the left pericardium.

  2007influential reference
• Differential regulation of Tbx5 protein expression and sub-cellular localization during heart development.

  2007cited by this paper
• Epicardial Cells of Human Adults Can Undergo an Epithelial‐to‐Mesenchymal Transition and Obtain Characteristics of Smooth Muscle Cells In Vitro

  2007cited by this paper
• Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.

  2007cited by this paper
• PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains

  2006cited by this paper
• F110I and R278C Troponin T Mutations That Cause Familial Hypertrophic Cardiomyopathy Affect Muscle Contraction in Transgenic Mice and Reconstituted Human Cardiac Fibers*

  2005cited by this paper
• Analysis of the proepicardium–epicardium transition during the malformation of the RXRα−/− epicardium

  2005cited by this paper
• Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

  2004cited by this paper
• A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: the ADAMTS family.

  2004cited by this paper
• A role for Tbx5 in proepicardial cell migration during cardiogenesis.

  2004influential reference
• Dual functions of α4β1 integrin in epicardial development

  2002cited by this paper
• Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia

  2002cited by this paper
• Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment.

  2002cited by this paper
• A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.

  2001influential reference
• TBX5 transcription factor regulates cell proliferation during cardiogenesis.

  2001cited by this paper
• Identification and localization of TBX5 transcription factor during human cardiac morphogenesis

  2000cited by this paper
• Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.

  1999cited by this paper
• Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

  1997cited by this paper
• Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.

  1997cited by this paper
• Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

  1997cited by this paper
• Pericardial mesoderm generates a population of coronary smooth muscle cells migrating into the heart along with ingrowth of the epicardial organ.

  1996cited by this paper
• Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels.

  1992cited by this paper
• In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species.

  1991cited by this paper

• Tbx genes influence early gene expression and photoreceptor patterning in the chick retina.

  2026cites this paper
• Tbx genes influence early gene expression and photoreceptor patterning in the chick retina

  2025cites this paper
• Single-nuclei multiomics analysis identifies abnormal cardiomyocytes in a murine model of cardiac development

  2025cites this paper
• Exploring the Function of Epicardial Cells Beyond the Surface

  2024cites this paper
• TBX5 genetic variants and SCD-CAD susceptibility: insights from Chinese Han cohorts

  2024cites this paper
• Congenital Coronary Blood Vessel Anomalies: Animal Models and the Integration of Developmental Mechanisms.

  2024cites this paper
• Role of Agrin in tissue repair and regeneration: From mechanisms to therapeutic opportunities (Review)

  2024cites this paper
• The Transcription Factor Tbx5-Dependent Epigenetic Modification Contributes to Neuropathic Allodynia by Activating TRPV1 Expression in the Dorsal Horn

  2024cites this paper
• Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation

  2023cites this paper
• Deciphering the Involvement of the Epicardium in Cardiac Diseases

  2023cites this paper
• EZH2 controls epicardial cell migration during heart development

  2023cites this paper
• Differential Spatio-Temporal Regulation of T-Box Gene Expression by microRNAs during Cardiac Development

  2021cites this paper
• Retinoic acid signaling in heart development: Application in the differentiation of cardiovascular lineages from human pluripotent stem cells

  2021cites this paper
• Human iPS-derived pre-epicardial cells direct cardiomyocyte aggregation expansion and organization in vitro

  2021cites this paper
• Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles

  2021cites this paper
• Agrin-YAP promotes the proliferation of epicardial cells.

  2020cites this paper
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  2020cites this paper
• Identification and functional analysis of genetic variants in TBX5 gene promoter in patients with acute myocardial infarction

  2019cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
• Harnessing Epicardial Progenitor Cells and Their Derivatives for Rescue and Repair of Cardiac Tissue After Myocardial Infarction

  2017cites this paper
• Signalling Pathways in Embryonic Development

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
• Molecular Pathways and Animal Models of Coronary Artery Anomalies

  2016cites this paper
• Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development.

  2016cites this paper
• Holt Oram syndrome: a case report and review of the literature.

  2016cites this paper
• Heme oxygenase in cardiac repair and regeneration.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
• Molecular basis of the clinical features of Holt-Oram syndrome resulting from missense and extended protein mutations of the TBX5 gene as well as TBX5 intragenic duplications.

  2015cites this paper