Involvement of DMT1 +IRE in the transport of lead in an in vitro BBB model.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Toxicology in Vitro

• Publication date

  2011-06-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.tiv.2009.11.006PMID 19913089
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Lead and Cadmium Synergistically Enhance the Expression of Divalent Metal Transporter 1 Protein in Central Nervous System of Developing Rats

  2009cited by this paper
• Iron Deficiency in Young Lebanese Children: Association With Elevated Blood Lead Levels

  2008cited by this paper
• Low level environmental lead exposure--a continuing challenge.

  2008cited by this paper
• Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood-brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media.

  2008cited by this paper
• Inhibition of Hypoxia-Induced Increase of Blood-Brain Barrier Permeability by YC-1 through the Antagonism of HIF-1α Accumulation and VEGF Expression

  2007cited by this paper
• Iron supplement prevents lead-induced disruption of the blood-brain barrier during rat development.

  2007cited by this paper
• Iron/IRP-1-dependent regulation of mRNA expression for transferrin receptor, DMT1 and ferritin during human erythroid differentiation.

  2007cited by this paper
• Association between acute lead exposure in indoor firing ranges and iron metabolism.

  2006cited by this paper
• Increased uptake of divalent metals lead and cadmium into the brain after kainite-induced neuronal injury

  2006cited by this paper
• Brain capillary endothelial cells mediate iron transport into the brain by segregating iron from transferrin without the involvement of divalent metal transporter 1

  2006cited by this paper
• Intellectual impairment in children with blood lead concentrations below 10 microg per deciliter.

  2003cited by this paper
• DMT1, a physiologically relevant apical Cu1+ transporter of intestinal cells.

  2003cited by this paper
• Intellectual Impairment in Children with Blood Lead Concentrations below 10 μg per Deciliter

  2003cited by this paper
• Interaction between flavonoids and the blood–brain barrier: in vitro studies

  2003cited by this paper
• Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element.

  2002cited by this paper
• Effect of the iron chelator desferrioxamine on manganese‐induced toxicity of rat pheochromocytoma (PC12) cells

  2002cited by this paper
• A comparison of the induction of immortalized endothelial cell impermeability by astrocytes

  2001cited by this paper
• Recurrence of hepatitis C after liver transplantation is associated with increased systemic IL-10 levels.

  2001cited by this paper
• Differential Localization of Divalent Metal Transporter 1 with and without Iron Response Element in Rat PC12 and Sympathetic Neuronal Cells

  2000cited by this paper
• The cell biology of the blood-brain barrier.

  1999cited by this paper
• Evaluation of an in vitro coculture model for the blood-brain barrier: Comparison of human umbilical vein endothelial cells (ECV304) and rat glioma cells (C6) from two commercial sources

  1999cited by this paper
• The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms.

  1998cited by this paper
• Cloning and characterization of a mammalian proton-coupled metal-ion transporter

  1997cited by this paper
• Lead-induced abnormalities in blood-brain barrier permeability in experimental chronic toxicity.

  1997cited by this paper
• Properties of an immortalised vascular endothelial/glioma cell co‐culture model of the blood‐brain barrier

  1996cited by this paper
• Experimental lead encephalopathy in the suckling rat: concentration of lead in cellular fractions enriched in brain capillaries.

  1978cited by this paper

• Mitochondrial iron deficiency mediated inhibition of ecdysone synthesis underlies lead (Pb) induced developmental toxicity in Drosophila melanogaster.

  2025cites this paper
• Bismuth release from endodontic materials: Proposed mechanisms for systemic circulation and organ accumulation.

  2025cites this paper
• Effects of xenobiotics on the blood-brain barrier and neural gene expression

  2024cites this paper
• Polystyrene microplastics mitigate lead-induced neurotoxicity by reducing heavy metal uptake in zebrafish larvae.

  2024cites this paper
• Pb induces ferroptosis in choroid plexus epithelial cells via Fe metabolism.

  2023cites this paper
• Occupational Lead Exposure Ototoxicity Evaluated With Distortion-Product Otoacoustic Emissions

  2023cites this paper
• Effects of Vitamin C and Magnesium L-threonate Treatment on Learning and Memory in Lead-poisoned Mice

  2021influential citation
• MOLECULAR MECHANISMS OF LEAD NEUROTOXICITY.

  2021cites this paper
• Experimental animal models of drug-induced sensorineural hearing loss: a narrative review

  2021cites this paper
• Correlation between urinary KIM‐1 and kidney protein expression of p‐ERK following damage in rats exposed to gentamicin or lead acetate

  2021cites this paper
• Oxidative stress caused by lead (Pb) induces iron deficiency in Drosophila melanogaster.

  2020cites this paper
• Environmental neurotoxic pollutants: review

  2020cites this paper
• Intracellular nickel accumulation induces apoptosis and cell cycle arrest in human astrocytic cells.

  2020cites this paper
• Lead exposure induces metabolic reprogramming in rat models.

  2020cites this paper
• Environmental toxic agents: The impact of heavy metals and organochlorides on brain development.

  2020cites this paper
• Assessment of the effect of post-natal lead exposure on the hippocampus of developing Wistar rats

  2019cites this paper
• Ecogenetics of lead toxicity and its influence on risk assessment

  2019cites this paper
• Binding of Pb-Melatonin and Pb-(Melatonin-metabolites) complexes with DMT1 and ZIP8: implications for lead detoxification

  2019cites this paper
• Neuregulin-1 attenuates experimental cerebral malaria (ECM) pathogenesis by regulating ErbB4/AKT/STAT3 signaling

  2018cites this paper
• Blood‐brain barrier development: Systems modeling and predictive toxicology

  2017cites this paper
• Neurotoxicity of Metal Mixtures.

  2017cites this paper
• In Vitro CNS Models

  2017cites this paper
• Effectiveness of ferric sodium edentate supplementation in children with lead poisoning

  2017cites this paper
• Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain barrier model

  2017influential citation
• Rhamnose‐coated superparamagnetic iron‐oxide nanoparticles: an evaluation of their in vitro cytotoxicity, genotoxicity and carcinogenicity

  2016cites this paper
• The History, Status, Gaps, and Future Directions of Neurotoxicology in China

  2016cites this paper
• Ototoxicity of Divalent Metals

  2016cites this paper
• Lead neurotoxicity: exploring the potential impact of lead substitution in zinc-finger proteins on mental health.

  2016cites this paper
• Causality pattern of the blood lead, monoamine oxidase A, and serotonin levels in brass home industry workers chronically exposed to lead

  2016cites this paper
• In vitro model of the blood-brain barrier established by co-culture of primary cerebral microvascular endothelial and astrocyte cells

  2015cites this paper
• Inflammation Modulates RLIP76/RALBP1 Electrophile-Glutathione Conjugate Transporter and Housekeeping Genes in Human Blood-Brain Barrier Endothelial Cells

  2015cites this paper
• Melanoma Cells Homing to the Brain: An In Vitro Model

  2015cites this paper
• Local salt substitutes “Obu-otoyo” activate acetylcholinesterase and butyrylcholinesterase and induce lipid peroxidation in rat brain

  2015cites this paper
• Influence of Iron Supplementation on DMT1 (IRE)-induced Transport of Lead by Brain Barrier Systems in vivo.

  2015cites this paper
• Mechanisms of Heavy Metal Neurotoxicity: Lead and Manganese

  2015influential citation
• Iron Regulatory Protein 1 Suppresses Hypoxia‐Induced Iron Uptake Proteins Expression and Decreases Iron Levels in HepG2 Cells

  2015cites this paper
• Mir-203-mediated tricellulin mediates lead-induced in vitro loss of blood-cerebrospinal fluid barrier (BCB) function.

  2015cites this paper
• Selection and combination of biomarkers to control and prevent the risk of occupational exposure to the mixture of lead, arsenic and manganese

  2014cites this paper
• Arsenic and Manganese Alter Lead Deposition in the Rat

  2014cites this paper
• In Vitro Models of CNS Barriers

  2014cites this paper
• Mechanisms of lead and manganese neurotoxicity.

  2013cites this paper
• Lead exposure results in hearing loss and disruption of the cochlear blood-labyrinth barrier and the protective role of iron supplement.

  2013cites this paper
• Cellular transport and homeostasis of essential and nonessential metals.

  2012cites this paper
• Early Postnatal Lead Exposure Induces Tau Phosphorylation in the Brain of Young Rats

  2012cites this paper
• Effects of chronic lead exposure on functions of nervous system in Chinese children and developmental rats.

  2012cites this paper
• In vitro models of the blood-brain barrier.

  2011cites this paper
• Toxicity of fatty acids on ECV-304 endothelial cells.

  2011cites this paper