Hsp90 Inhibition Decreases Mitochondrial Protein

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• A proteomics approach to identify the ubiquitinated proteins in mouse heart.

  2007cited by this paper
• PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1

  2007cited by this paper
• Heat Shock Protein 75 (TRAP1) Antagonizes Reactive Oxygen Species Generation and Protects Cells from Granzyme M-mediated Apoptosis*

  2007cited by this paper
• Multidimensional Protein Identification Technology (MudPIT) Analysis of Ubiquitinated Proteins in Plants*S

  2007cited by this paper
• Turning Off Estrogen Receptor β-Mediated Transcription Requires Estrogen-Dependent Receptor Proteolysis

  2006cited by this paper
• Proteasome inhibition induces differential heat shock protein response but not unfolded protein response in HepG2 cells

  2006cited by this paper
• Quantitative monitoring of autophagic degradation.

  2006cited by this paper
• A Tandem Affinity Tag for Two-step Purification under Fully Denaturing Conditions

  2006cited by this paper
• Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells.

  2006cited by this paper
• Erythroid-specific 5-aminolevulinate synthase protein is stabilized by low oxygen and proteasomal inhibition.

  2005cited by this paper
• Large‐scale analysis of the human ubiquitin‐related proteome

  2005cited by this paper
• Signaling through monoubiquitination.

  2004cited by this paper
• Distinct Steps in Dislocation of Luminal Endoplasmic Reticulum-associated Degradation Substrates

  2004cited by this paper
• Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

  2004cited by this paper
• Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.

  2004cited by this paper
• Targeting multiple signal transduction pathways through inhibition of Hsp90

  2004cited by this paper
• Regulation of 17-AAG-induced apoptosis: role of Bcl-2, Bcl-XL, and Bax downstream of 17-AAG-mediated down-regulation of Akt, Raf-1, and Src kinases.

  2003cited by this paper
• Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery 1

  2003cited by this paper
• A proteomics approach to understanding protein ubiquitination

  2003cited by this paper
• Hyperubiquitination of proteins in dilated cardiomyopathy

  2003cited by this paper
• Endoplasmic reticulum-associated protein degradation.

  2003cited by this paper
• Ubiquitination of Prohibitin in Mammalian Sperm Mitochondria: Possible Roles in the Regulation of Mitochondrial Inheritance and Sperm Quality Control1

  2003cited by this paper
• Flow cytometry and GFP: A novel assay for measuring the import and turnover of nuclear‐encoded mitochondrial proteins in live PC12 cells

  2003cited by this paper
• c-MYC apoptotic function is mediated by NRF-1 target genes.

  2003cited by this paper
• Heat Shock Protein 90 Modulates the Unfolded Protein Response by Stabilizing IRE1α

  2002cited by this paper
• ErbB2 overexpression in an ovarian cancer cell line confers sensitivity to the HSP90 inhibitor geldanamycin.

  2002cited by this paper
• Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3'-kinase-AKT-dependent pathway.

  2002cited by this paper
• ER-associated degradation in protein quality control and cellular regulation.

  2002cited by this paper
• The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy

  2001cited by this paper
• Cytochrome c Oxidase-deficient Patients Have Distinct Subunit Assembly Profiles*

  2001cited by this paper
• Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells

  2001cited by this paper
• The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

  2000cited by this paper
• In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

  2000cited by this paper
• Degradation of unassembled soluble Ig subunits by cytosolic proteasomes: evidence that retrotranslocation and degradation are coupled events

  2000cited by this paper
• Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity.

  2000cited by this paper
• Flow cytometric measurement of mitochondrial mass and function: A novel method for assessing chemoresistance

  1998cited by this paper
• A novel fluorescent marker for assembled mitochondria ATP synthase of yeast

  1997cited by this paper
• Mitochondrial Proliferation and Paradoxical Membrane Depolarization during Terminal Differentiation and Apoptosis in a Human Colon Carcinoma Cell Line

  1997cited by this paper
• Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.

  1994cited by this paper
• Dynamics, structure, and function are coupled in the mitochondrial matrix.

  1991cited by this paper
• Two-dimensional gel electrophoretic resolution of the polypeptides of rat liver mitochondria and the outer membrane.

  1990cited by this paper

• Micropatterning control of tubular commitment in human adult renal stem cells.

  2016cites this paper
• Modulating Molecular Chaperones Improves Mitochondrial Bioenergetics and Decreases the Inflammatory Transcriptome in Diabetic Sensory Neurons.

  2015cites this paper