Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Cell Death and Differentiation

• Publication date

  2018-02-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/s41418-019-0332-7PMID 31068677PMCID PMC7224178
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sequence Analysis

  2020cited by this paper
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  2019cited by this paper
• Multicilin and activated E2f4 induce multiciliated cell differentiation in primary fibroblasts

  2018cited by this paper
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  2018cited by this paper
• The development and functions of multiciliated epithelia

  2017cited by this paper
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  2017cited by this paper
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  2017cited by this paper
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  2017cited by this paper
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  2017cited by this paper
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  2017cited by this paper
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  2016cited by this paper
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  2016cited by this paper
• GEMC1 is a critical regulator of multiciliated cell differentiation

  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
• Small tubules, surprising discoveries: from efferent ductules in the turkey to the discovery that estrogen receptor alpha is essential for fertility in the male.

  2015influential reference
• Ciliary function and motor protein composition of human fallopian tubes.

  2015cited by this paper
• Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

  2014cited by this paper
• TAp73 is required for spermatogenesis and the maintenance of male fertility

  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2012cited by this paper
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  2012cited by this paper
• Cutadapt removes adapter sequences from high-throughput sequencing reads

  2011cited by this paper
• A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
• Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

  2011cited by this paper
• Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation

  2011cited by this paper
• Regulation of Fertility by the p53 Family Members.

  2011cited by this paper
• Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

  2011cited by this paper
• Regulation of female reproduction by p53 and its family members

  2011cited by this paper
• Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression*

  2011cited by this paper
• Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

  2011cited by this paper
• E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis

  2010cited by this paper
• MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia

  2010cited by this paper
• Ependymal cells: biology and pathology

  2009cited by this paper
• Three‐Dimensional Reconstruction of Efferent Ducts in Wild‐Type and Lgr4 Knock‐Out Mice

  2009cited by this paper
• miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

  2009cited by this paper
• Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus

  2009cited by this paper
• microRNA-449 is a putative regulator of choroid plexus development and function.

  2009cited by this paper
• DeltaNp73 regulates neuronal survival in vivo

  2009cited by this paper
• TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.

  2008cited by this paper
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  2008cited by this paper
• Development and Notch Signaling Requirements of the Zebrafish Choroid Plexus

  2008cited by this paper
• The graded response to Sonic Hedgehog depends on cilia architecture.

  2007cited by this paper
• Altered pHi regulation and Na+/HCO3− transporter activity in choroid plexus of cilia-defective Tg737orpk mutant mouse

  2007cited by this paper
• E2f4 is required for normal development of the airway epithelium.

  2007cited by this paper
• Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse.

  2007cited by this paper
• Defective postnatal development of the male reproductive tract in LGR4 knockout mice.

  2006cited by this paper
• The reproductive significance of human Fallopian tube cilia.

  2006cited by this paper
• Adult Ependymal Cells Are Postmitotic and Are Derived from Radial Glial Cells during Embryogenesis

  2005cited by this paper
• Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus

  2005cited by this paper
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  2004cited by this paper
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  2002cited by this paper
• The Epididymis: From Molecules to Clinical Practice

  2002cited by this paper
• p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

  2000cited by this paper
• Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice.

  2000cited by this paper
• Forkhead transcription factor HFH-4 expression is temporally related to ciliogenesis.

  1999cited by this paper
• Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry.

  1998cited by this paper
• Morphology and ultrastructure of fallopian tube epithelium at different stages of the menstrual cycle and menopause.

  1994cited by this paper
• Structure and function of the ductuli efferentes: A review

  1994cited by this paper
• [Cellular receptors for animal viruses].

  1968cited by this paper

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  2025cites this paper
• SOX2 commands LIM homeobox transcription factors in choroid plexus development and tumorigenesis

  2025cites this paper
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