Fluorescence lifetime imaging of fluorescent proteins as an effective quantitative tool for noninvasive study of intracellular processes

S. Levchenko,A. Pliss,J. Qu

Published 2018 in Journal of Innovative Optical Health Sciences

ABSTRACT

Fluorescence lifetime imaging (FLIM) is an effective noninvasive bioanalytical tool based on measuring fluorescent lifetime of fluorophores. A growing number of FLIM studies utilizes genetically engineered fluorescent proteins targeted to specific subcellular structures to probe local molecular environment, which opens new directions in cell science. This paper highlights the unconventional applications of FLIM for studies of molecular processes in diverse organelles of live cultured cells.

PUBLICATION RECORD

  • Publication year

    2018

  • Venue

    Journal of Innovative Optical Health Sciences

  • Publication date

    Unknown publication date

  • Fields of study

    Biology, Medicine, Engineering

  • Identifiers
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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