Mechanisms of antibiotic resistance in Haemophilus parainfluenzae

Regina Esinam Abotsi,Usha Govinden,S. Essack

Published 2017 in Southern African Journal of Infectious Diseases

ABSTRACT

Haemophilus parainfluenzae is part of the HACEK group of fastidious bacteria commonly implicated in endocarditis and bacteremia. Previously considered as a normal respiratory, oral and sometimes genitourinary commensal, it has been recognised as a pathogen that can cause life-threatening infections in both immunocompromised and healthy individuals. It has also been reported as a bacterium that can harbor transferable antibiotic resistance genes. This paper presents a literature review on the molecular mechanisms of resistance of H. parainfluenzae to commonly prescribed antibiotics and discusses areas for further research.

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