Quantification of deficits in lateral paw positioning after spinal cord injury in dogs

BackgroundPrevious analysis of the behavioural effects of spinal cord injury has focussed on coordination in the sagittal plane of movement between joints, limb girdle pairs or thoracic and pelvic limb pairs. In this study we extend the functional analysis of the consequences of clinical thoracolumbar spinal cord injury in dogs to quantify the well-recognised deficits in lateral stability during locomotion. Dogs have a high centre of mass thereby facilitating recognition of lateral instability.ResultsWe confirm that errors in lateral positioning of the pelvic limb paws can be quantified and that there is a highly significant difference in variability of foot placement between normal and spinal cord injured dogs. In this study there was no detectable difference in lateral paw positioning variability between complete and incomplete injuries, but it appears that intergirdle limb coordination and appropriate lateral paw placement recover independently from one another.ConclusionAnalysis of lateral paw position in the dog provides an additional tier of analysis of outcome after spinal cord injury that will be of great value in interpreting the effects of putative therapeutic interventions.

• Publication year

  2008

• Venue

  BMC Veterinary Research

• Publication date

  2008-11-25

• Fields of study

  Medicine

• Identifiers
  DOI 10.1186/1746-6148-4-47PMID 19032742PMCID 2631515
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury

  2008cited by this paper
• Stride-to-stride variability while enumerating animal names among healthy young adults: result of stride velocity or effect of attention-demanding task?

  2008cited by this paper
• Step Training Reinforces Specific Spinal Locomotor Circuitry in Adult Spinal Rats

  2008influential reference
• Optimal sensorimotor transformations for balance

  2007cited by this paper
• Development of a universal measure of quadrupedal forelimb-hindlimb coordination using digital motion capture and computerised analysis

  2007influential reference
• Walking index for spinal cord injury.

  2007cited by this paper
• Neural bases of postural control.

  2006cited by this paper
• Clinical canine spinal cord injury provides an opportunity to examine the issues in translating laboratory techniques into practical therapy

  2006cited by this paper
• Different patterns of fore-hindlimb coordination during overground locomotion in cats with ventral and lateral spinal lesions

  2004cited by this paper
• Postural control in the rabbit maintaining balance on the tilting platform.

  2003cited by this paper
• Gait variability and fall risk in community-living older adults: a 1-year prospective study.

  2001cited by this paper
• Development of a functional scoring system in dogs with acute spinal cord injuries.

  2001cited by this paper
• Walking index for spinal cord injury (WISCI): an international multicenter validity and reliability study

  2000cited by this paper
• Postural control in the lamprey: A study with a neuro-mechanical model.

  2000cited by this paper
• Weight support and balance during perturbed stance in the chronic spinal cat.

  1999cited by this paper
• Acceleration and balance in trotting dogs.

  1999cited by this paper
• Attributes of quiet stance in the chronic spinal cat.

  1999cited by this paper
• Effect of head position on postural orientation and equilibrium

  1998cited by this paper
• Differential effects of the reticulospinal system on locomotion in lamprey.

  1998cited by this paper
• Recovery of locomotion after ventral and ventrolateral spinal lesions in the cat. I. Deficits and adaptive mechanisms.

  1998cited by this paper
• International Standards for Neurological and Functional Classification of Spinal Cord Injury

  1997cited by this paper
• Different forms of impairment of the fore-hindlimb coordination after partial spinal lesions in cats.

  1996cited by this paper
• Control of locomotion in the decerebrate cat.

  1996cited by this paper
• Locomotor capacities after complete and partial lesions of the spinal cord.

  1996cited by this paper
• Spatial orientation in the lamprey. I. Control of pitch and roll

  1995cited by this paper
• Spatial orientation in the lamprey. II. Visual influence on orientation during locomotion and in the attached state

  1995cited by this paper
• A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats

  1995cited by this paper
• Stance control in the chronic spinal cat.

  1994cited by this paper
• Analyses of treadmill locomotion in adult spinal dogs.

  1990cited by this paper
• Intervertebral disc disease.

  1989cited by this paper
• Integration of posture and locomotion in acute decerebrate cats and in awake, freely moving cats.

  1987cited by this paper
• Textbook of small animal surgery

  1985cited by this paper
• Compensation of vestibular symptoms in hemilabyrinthectomized guinea pigs. Role of the sensorimotor activation.

  1983cited by this paper
• The Coefficient of Variation

  1946cited by this paper
• Abbreviated title: Effects of spinal lesions on postural control Text pages: 37

  year unknowncited by this paper

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  2023cites this paper
• Quantification of phenobarbital-induced ataxia in dogs with idiopathic epilepsy

  2023cites this paper
• Adaptation of land treadmill scoring system for underwater treadmill in dogs with thoracolumbar intervertebral disc extrusion.

  2023cites this paper
• Quantification of spinal ataxia in dogs with thoracolumbar spinal cord injury

  2023cites this paper
• Treadmill-Based Gait Kinematics in the Yucatan Mini Pig

  2020cites this paper
• Comparison of Gait Assessment Scales in Dogs with Spinal Cord Injury from Intervertebral Disc Herniation

  2020cites this paper
• Ambulation in Dogs With Absent Pain Perception After Acute Thoracolumbar Spinal Cord Injury

  2020cites this paper
• Development of a Novel Gait Analysis Tool Measuring Center of Pressure for Evaluation of Canine Chronic Thoracolumbar Spinal Cord Injury

  2019cites this paper
• Ovine model of neuropathic pain for assessing mechanisms of spinal cord stimulation therapy via dorsal horn recordings, von Frey filaments, and gait analysis

  2018cites this paper
• Kinetic and kinematic follow‐up gait analysis in Doberman Pinschers with cervical spondylomyelopathy treated medically and surgically

  2018cites this paper
• Quantifying center of pressure variability in chondrodystrophoid dogs.

  2017cites this paper
• An ovine model of spinal cord injury

  2017cites this paper
• Cavalier King Charles Spaniels with Chiari-like malformation and Syringomyelia have increased variability of spatio-temporal gait characteristics

  2017cites this paper
• Targeting Translational Successes through CANSORT-SCI: Using Pet Dogs To Identify Effective Treatments for Spinal Cord Injury

  2017cites this paper
• A simplified method of walking track analysis to assess short-term locomotor recovery after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs.

  2016influential citation
• Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain

  2016cites this paper
• Comparing the effects of first-line antiepileptic drugs on the gait of dogs with idiopathic epilepsy

  2016cites this paper
• Phase II Double-blinded Randomized Controlled Clinical Trial of Chondroitinase ABC by Intraspinal Injection for Treatment of Severe Chronic Spinal Cord Injury in 60 Pet Dogs

  2016cites this paper
• Recovery of stepping and coordination in dogs following acute thoracolumbar intervertebral disc herniations.

  2016cites this paper
• Kinetic and kinematic gait analysis in the pelvic limbs of normal and post-hemilaminectomy Dachshunds

  2016cites this paper
• Utility and repeatability of quantitative outcome measures to assess recovery after canine spinal cord injury

  2015cites this paper
• Kinematic analysis of the gait of adult sheep during treadmill locomotion: Parameter values, allowable total error, and potential for use in evaluating spinal cord injury.

  2015cites this paper
• A preliminary evaluation of the reliability of a modified functional scoring system for assessing neurologic function in ambulatory thoracolumbar myelopathy dogs

  2015cites this paper
• Development of a neuromusculoskeletal computer model in a chondrodystrophic dog.

  2015cites this paper
• Rehabilitation and physical therapy for the neurologic veterinary patient.

  2015cites this paper
• Stem Cells in Canine Spinal Cord Injury – Promise for Regenerative Therapy in a Large Animal Model of Human Disease

  2015cites this paper
• Gait scoring in dogs with thoracolumbar spinal cord injuries when walking on a treadmill

  2014influential citation
• Acute spinal cord injury: tetraplegia and paraplegia in small animals.

  2014cites this paper
• Three-dimensional kinematic gait analysis of Doberman Pinschers with and without cervical spondylomyelopathy.

  2013cites this paper
• Intracranial Somatosensory Responses with Direct Spinal Cord Stimulation in Anesthetized Sheep

  2013cites this paper
• Using Naturally Occurring Spinal Cord Injury in Domestic Dogs to Explore Novel Therapeutic Options

  2013cites this paper
• Soft-coupling suspension system for an intradural spinal cord stimulator: Biophysical performance characteristics

  2013cites this paper
• Animal Models of Spinal Cord Injury

  2013cites this paper
• Autologous olfactory mucosal cell transplants in clinical spinal cord injury: a randomized double-blinded trial in a canine translational model

  2012cites this paper
• Designing clinical trials in canine spinal cord injury as a model to translate successful laboratory interventions into clinical practice

  2011cites this paper