Symmetric image normalization for mouse brain magnetic resonance microscopy

Various genetic mouse models have been used to understand aspects of the biology of the neurodegenerative disease. A rapid growth of data collection from the mouse brain has put image registration, a key prerequisite step for brain image analysis in great focus. SyN (symmetric image normalization method) is one of the most performed diffeomorphic strategies which has been widely used in human brain mapping. In this study, we optimized the SyN strategy for tiny mouse brain. The optimized protocol is able to accurately remove the anatomical variability between mouse brain MR microscopy (MRM) and offers superior performance over the SyN protocol for human.

• Publication year

  2016

• Venue

  Unknown venue

• Publication date

  2016-04-09

• Fields of study

  Medicine, Computer Science, Engineering

• Identifiers
  DOI 10.2991/AMEII-16.2016.180
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Mouse brain magnetic resonance microscopy: Applications in Alzheimer disease

  2015cited by this paper
• Atlas-based automatic mouse brain image segmentation revisited: model complexity vs. image registration.

  2012cited by this paper
• Diffeomorphic registration using geodesic shooting and Gauss–Newton optimisation

  2011cited by this paper
• A reproducible evaluation of ANTs similarity metric performance in brain image registration

  2011cited by this paper
• Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration

  2009influential reference
• Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain

  2008cited by this paper
• Et al

  2008cited by this paper
• Comprar The Mouse Brain in Stereotaxic Coordinates, The coronal plates and diagrams Compact, 3rd Edition | Keith Franklin | 9780123742445 | Academic Press

  2008cited by this paper
• A fast diffeomorphic image registration algorithm

  2007cited by this paper
• Unified segmentation

  2005cited by this paper
• Computing Large Deformation Metric Mappings via Geodesic Flows of Diffeomorphisms

  2005cited by this paper
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  2003cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• HAMMER: hierarchical attribute matching mechanism for elastic registration

  2002cited by this paper
• Nonrigid registration using free-form deformations: application to breast MR images

  1999cited by this paper
• Image matching as a diffusion process: an analogy with Maxwell's demons

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  2021cites this paper
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  2019cites this paper
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