Synaptic sites on reinnervated nerve cells visualized at two different times in living mice

Synaptic boutons on the surface of identified autonomic ganglion cells were visualized by methylene blue staining at intervals of 1–2 months following denervation to assess whether regenerating axon terminals reoccupy original synaptic sites. The distribution of synapses observed on the same neuronal cell bodies was almost always different in appearance after reinnervation. These results are at odds with the conclusions of earlier workers, who have argued that mammalian neurons bear a fixed number of synaptic sites, which are reoccupied during reinnervation.

• Publication year

  1987

• Venue

  Journal of Neuroscience

• Publication date

  1987-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1523/JNEUROSCI.07-05-01492.1987PMID 3572488PMCID PMC6568834
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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